Effect of physical exercise on mortality in patients with Parkinson's disease
Abstract
Public health nurses visited and followed up for more than one year 438 patients with Parkinson's disease living in Osaka. The follow-up period averaged 4.1 years, during which 71 deaths were observed. The patients were classified according to the degree of physical exercise they performed, and the ratios of observed to expected deaths were calculated. The exercising group showed the lowest ratio of 1.68 (1.45 for patients able to walk independently, and 1.89 for those could not) while all patients exhibited a ratio of 2.47. Multivariate analysis using Cox's proportional hazard model, adjusted for age, sex, walking ability and duration of disease at study entry, showed that, compared with the exercising group, the non-exercising patients had a hazard ratio of 1.83.
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Longevity in Parkinson disease has been associated with physical exercise.
“Finally, longevity in PD has been associated with physical exercise.11”
From Does vigorous exercise have a neuroprotective effect in Parkinson disease? (2011) · cites this paper as [11]
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Does vigorous exercise have a neuroprotective effect in Parkinson disease?
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- Authors
- Kuroda, K., Tatara, K., Takatorige, T., & Shinsho, F.
- Affiliations
- The University of Osaka (JP)
- Corresponding author
- Kuroda, K.
- ORCID
- Kuroda, K.
- Venue
- Acta Neurologica Scandinavica
- Publisher
- Wiley
- Published
- 1992-07
- Volume
- 86
- Issue
- 1
- Pages
- 55-59
- ISSN
- 0001-6314 (ISSN-L)
- 1600-0404
- OpenAlex
- W2003463537
- Cited by
- 98
- References
- 21
- Citations by year
- 2026: 1 · 2025: 1 · 2023: 1 · 2022: 6 · 2021: 2 · 2020: 1 · 2019: 4 · 2018: 4 · 2017: 4 · 2015: 4 · 2014: 4 · 2013: 9 · 2012: 3
- FWCI
- 1.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Neurologica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
- Keywords
- Parkinson's disease, physical activity, mortality, walking ability, public health nursing, long-term follow-up
- MeSH terms
- Female, Humans, Japan, Male, Middle Aged, Neurologic Examination, Parkinson Disease, Exercise, Survival Rate, Proportional Hazards Models
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