Cited by 33Treatment of Major DepressionElectroconvulsive Therapy StudiesBipolar Disorder and Treatment

Antidepressant withdrawal syndromes: phenomenology and pathophysiology

Dilsaver, S. C.·1989·Acta Psychiatrica Scandinavica

Abstract

ABSTRACT The literature reporting signs and symptoms produced by the abrupt or gradual withdrawal of antidepressants is reviewed. Patients with antidepressant withdrawal syndromes are presented and principles governing their care are highlighted. Finally, the author summarizes evidence that antidepressant‐induced supersensitiviry of central and peripheral muscarinic cholinergic mechanisms may account for commonly observed antidepressant withdrawal phenomena.

Integrity signals

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Crossref · 10.1111/j.1600-0447.1989.tb08578.x

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39 of 39 references verified0 citation errors · 0 not checkable

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Authors
Dilsaver, S. C.
Affiliations
The Ohio State University (US)
Corresponding author
Dilsaver, S. C.
Venue
Acta Psychiatrica Scandinavica
Publisher
Wiley
Published
1989-02
Volume
79
Issue
2
Pages
113-117
ISSN
  • 0001-690X (ISSN-L)
  • 1600-0447
OpenAlex
W2051372625
Cited by
33
References
39
Citations by year
2023: 1 · 2020: 1 · 2015: 1 · 2013: 1 · 2012: 1
FWCI
2.02
Type
journal article
Language
en
Open access
closed
Locations
  • Acta Psychiatrica Scandinavica (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Mental Health (MH005530-3)
Topics
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
  • Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Keywords
antidepressant withdrawal syndrome, antidepressant discontinuation, antidepressant withdrawal symptoms, pathophysiology, cholinergic mechanisms, patient care
MeSH terms
Adult, Antidepressive Agents, Anxiety, Bipolar Disorder, Depressive Disorder, Female, Gastrointestinal Diseases, Humans, Male, Middle Aged, Parkinson Disease, Secondary, Receptors, Muscarinic, Recurrence, Sleep Wake Disorders, Substance Withdrawal Syndrome

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