The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Neuropeptide Y: an overview of central distribution, functional aspects, and possible involvement in neuropsychiatric illnesses
Abstract
Neuropeptide Y (NPY) was first discovered and characterized as a 36‐amino‐acid peptide neurotransmitter in 1982. It is widely distributed in the central nervous system, with particularly high concentrations within several limbic and cortical regions. A number of co‐localizations with other neuromessengers such as noradrenaline, somatostatin, and gamma‐aminobutyric acid have been demonstrated. A large number of physiological and pharmacological actions of NPY have been suggested. Recent clinical data also suggest the involvement of NPY in several neuropsychiatric illnesses, particularly in depressive and anxiety states. This article gives a comprehensive review of central distribution of NPY and its receptors, co‐localizations and interactions with other neuromessengers, genetic aspects, pharmacological and physiological actions, influence on neuroendocrine functions, and possible involvement in various neuropsychiatric illnesses.
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Cites
Glenn Stanley, B., Kyrkouli, S. E., Lampert, S., & Leibowitz, S. F. (1986) · Peptides · doi:10.1016/0196-9781(86)90149-x · Cited by 849
Neuropeptide Y: Direct and indirect action on insulin secretion in the rat
Moltz, J. H., & McDonald, J. K. (1985) · Peptides · doi:10.1016/0196-9781(85)90443-7 · Cited by 213
Neuropeptide Y increases food intake in mice
Morley, J. E., Hernandez, E. N., & Flood, J. F. (1987) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1987.253.3.r516 · Cited by 164
Cited by
Neurobiological similarities in depression and drug dependence: a self-medication hypothesis
Markou, A. (1998) · Neuropsychopharmacology · doi:10.1016/s0893-133x(97)00113-9 · Cited by 767
Modulation of Anxiety and Neuropeptide Y-Y1 Receptors by Antisense Oligodeoxynucleotides
Wahlestedt, C., Pich, E. M., Koob, G. F., Yee, F., & Heilig, M. (1993) · Science · doi:10.1126/science.8380941 · Cited by 527
Self-citationCloned human neuropeptide Y receptor couples to two different second messenger systems.
Herzog, H., Hort, Y. J., Ball, H. J., Hayes, G., Shine, J., & Selbie, L. A. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.13.5794 · Cited by 434
Corticotropin-releasing factor and neuropeptide y: role in emotional integration
Heilig, M., Koob, G. F., Ekman, R., & Britton, K. T. (1994) · Trends in Neurosciences · doi:10.1016/0166-2236(94)90079-5 · Cited by 324
Self-citationPlasma neuropeptide-Y concentrations in humans exposed to military survival training
Morgan, C. A., Wang, S., Southwick, S. M., Rasmusson, A., Hazlett, G., Hauger, R. L., & Charney, D. S. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00239-5 · Cited by 298
Metadata
- Authors
- Heilig, M., & Widerlöv, E.
- Venue
- Acta Psychiatrica Scandinavica
- Publisher
- Wiley
- Published
- 1990-08
- Volume
- 82
- Issue
- 2
- Pages
- 95-114
- ISSN
- 0001-690X (ISSN-L)
- 1600-0447
- OpenAlex
- W1987294827
- Cited by
- 176
- References
- 3
- FWCI
- 2.60
- Type
- journal article
- Language
- en
- Open access
- closed
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- Heilig, M., & Widerlöv, E. (1990). Neuropeptide Y: an overview of central distribution, functional aspects, and possible involvement in neuropsychiatric illnesses. Acta Psychiatrica Scandinavica. https://doi.org/10.1111/j.1600-0447.1990.tb01366.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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