The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Does platelet‐rich plasma promote remodeling of autologous bone grafts used for augmentation of the maxillary sinus floor?
Abstract
Abstract: The aim of this study was to evaluate the effect of platelet‐rich plasma (PRP) on remodeling of autologous bone grafts used for augmentation of the floor of the maxillary sinus. In five edentulous patients suffering from insufficient retention of their upper denture related to a severely resorbed maxilla, the floor of both maxillary sinus was augmented with an autologous bone graft from the iliac crest. Randomly, PRP was added to the bone graft used to augment the floor of the left or right sinus (split‐mouth design). Three months after the reconstruction, bone biopsies were taken with a trephine from the planned implant sites (N=30). Subsequently, three implants were placed in the left and right posterior maxilla. Microradiograms were made of all biopsies (N=30), whereafter the biopsies were processed for light microscopic examination. In addition, clinical parameters were scored. Wound healing was uneventful, clinically no difference was observed between the side treated with PRP or not. Also microradiographical and histomorphological examination of the biopsies revealed no statistical difference between the PRP‐ and non‐PRP side. One implant placed in the PRP side of the graft was lost during the healing phase. Implant‐retained overdentures were fabricated 6 months after implantation. All patients functioned well (follow‐up 20.2±4.3 months). In this study, no beneficial effect of PRP on wound healing and bone remodeling was observed. It is posed that PRP has no additional value in promoting healing of grafted non‐critical size defects.
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van Waarde, M. A. W. H., van Assen, A. J., Kampinga, H. H., Konings, A. W. T., & Vujaskovic, Z. (1997) · Analytical Biochemistry · doi:10.1006/abio.1997.2026 · Cited by 58
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New insights into and novel applications for platelet-rich fibrin therapies
Anitua, E., Sánchez, M., Nurden, A. T., Nurden, P., Orive, G., & Andía, I. (2006) · Trends in Biotechnology · doi:10.1016/j.tibtech.2006.02.010 · Cited by 527
Schallmoser, K., Bartmann, C., Rohde, E., Reinisch, A., Kashofer, K., Stadelmeyer, E., Drexler, C., Lanzer, G., Linkesch, W., & Strunk, D. (2007) · Transfusion · doi:10.1111/j.1537-2995.2007.01220.x · Cited by 503
Yang, H. S., Shin, J., Bhang, S. H., Shin, J.-Y., Park, J., Im, G.-I., Kim, C.-S., & Kim, B.-S. (2011) · Experimental and Molecular Medicine · doi:10.3858/emm.2011.43.11.070 · Cited by 147
Metadata
- Authors
- Raghoebar, G. M., Schortinghuis, J., Liem, R. S. B., Ruben, J. L., Van Der Wal, J. E., & Vissink, A.
- Venue
- Clinical Oral Implants Research
- Publisher
- Wiley
- Published
- 2005-03-03
- Volume
- 16
- Issue
- 3
- Pages
- 349-356
- ISSN
- 0905-7161 (ISSN-L)
- 1600-0501
- OpenAlex
- W2031676004
- Cited by
- 187
- References
- 1
- FWCI
- 14.47
- Type
- journal article
- Language
- en
- Open access
- closed
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- Raghoebar, G. M., Schortinghuis, J., Liem, R. S. B., Ruben, J. L., Van Der Wal, J. E., & Vissink, A. (2005). Does platelet‐rich plasma promote remodeling of autologous bone grafts used for augmentation of the maxillary sinus floor? Clinical Oral Implants Research. https://doi.org/10.1111/j.1600-0501.2005.01115.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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