The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patients
Abstract
Abstract The periodontal health of 30 adult epileptic patients treated with cither sodium valproate or phenytoin was compared with a control group (n= 15) of otherwise healthy patients. The 3 groups were matched for age and sex. Patients on phenytoin therapy showed significantly higher plaque scores (p < 0.05), gingival index (p < 0.05) and pocketing (P<0.05) than patients in the control group. The % of gingival hyperplusia was significantly higher (P < 0.05) in the phenytoin‐treated patients than those on sodium valproate or in the control group. However, patients on phenytoin therapy had significantly less bone loss than those on sodium valproale (p < 0.05) or in the control group (P < 0.01). No significant differences were observed between the sodium valproate group and the control group on any of the parameters assessed. The results from this study would suggest that sodium valproate has no unwanted effects on periodontal health and may be considered a safe alternative, regarding the periodontal aspects, to phenytoin for the treatment of adult onset epilepsy.
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Cites
Periodontal Disease in Pregnancy II. Correlation Between Oral Hygiene and Periodontal Condition
Silness, J., & Löe, H. (1964) · Acta Odontologica Scandinavica · doi:10.3109/00016356408993968 · Cited by 7,932
Cited by
The pathogenesis of drug‐induced gingival overgrowth
Seymour, R. A., Thomason, J. M., & Ellis, J. S. (1996) · Journal of Clinical Periodontology · doi:10.1111/j.1600-051x.1996.tb02072.x · Cited by 403
Self-citationPrevalence of Gingival Overgrowth Induced by Calcium Channel Blockers: A Community‐Based Study
Ellis, J. S., Seymour, R. A., Steele, J. G., Robertson, P., Butler, T. J., & Thomason, J. M. (1999) · Journal of Periodontology · doi:10.1902/jop.1999.70.1.63 · Cited by 273
Self-citationHallmon, W. W., & Rossmann, J. A. (1999) · Periodontology 2000 · doi:10.1111/j.1600-0757.1999.tb00175.x · Cited by 148
Gingival Enlargement in Children Treated With Antiepileptics
Tan, H., Gürbüz, T., & Dağsuyu, I. M. (2004) · Journal of Child Neurology · doi:10.1177/08830738040190120901 · Cited by 31
Gingival inflammation assessment by image analysis: measurement and validation
Smith, R., Lath, D., Rawlinson, A., Karmo, M., & Brook, A. (2008) · International Journal of Dental Hygiene · doi:10.1111/j.1601-5037.2008.00294.x · Cited by 30
Metadata
- Authors
- Seymour, R. A., Smith, D. G., & Turnbull, D. N.
- Venue
- Journal of Clinical Periodontology
- Publisher
- Wiley
- Published
- 1985-07
- Volume
- 12
- Issue
- 6
- Pages
- 413-419
- ISSN
- 0303-6979 (ISSN-L)
- 1600-051X
- OpenAlex
- W2032119905
- Cited by
- 178
- References
- 1
- FWCI
- 6.63
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patients. https://app.cochat.ai/papers/10.1111/j.1600-051x.1985.tb01377.x
- The paper
- Seymour, R. A., Smith, D. G., & Turnbull, D. N. (1985). The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patients. Journal of Clinical Periodontology. https://doi.org/10.1111/j.1600-051x.1985.tb01377.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
