The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Metronidazole plus amoxycillin in the treatment of Actinobacillus associated periodontitis
Abstract
Abstract The potential use of an adjunctive therapy of metronidazole plus cillin for the subgingival elimination of Actinobacillus actinomycetemcomitans in periodontitis patients was investigated. 22 patients participated in this study, 11 with localized juvenile periodontitis (LJP) and 11 with rapidly progressive periodontitis (RPP). 14 patients had received periodontal treatment in the past. All patients were subgingivally infected with A. actinomycetemcomitans. After mechanical subgingival debridement in combination with the antibiotic treatment, elimination of A. actinomycetemcomitans was achieved in all patients but one. With this one exception, clinical improvements were observed in all patients, resulting in reduced pocket probing depths as well as in a significant reduction in bleeding on probing. Re‐examination of 16 patients after 9–11 months revealed that A. actinomycetemcomitans was still undetectable and further clinical improvement was observed. It was concluded that the combination of metronidazole plus amoxycillin is a valuable adjunct to mechanical therapy in A. actinomycetemcomitans associated periodontal infections.
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Citations
Cites
Slots, J., & Genco, R. J. (1984) · Journal of Dental Research · doi:10.1177/00220345840630031101 · Cited by 939
Cited by
Microbial etiological agents of destructive periodontal diseases
Haffajee, A. D., & Socransky, S. S. (1994) · Periodontology 2000 · doi:10.1111/j.1600-0757.1994.tb00020.x · Cited by 1,623
Dental biofilms: difficult therapeutic targets
SOCRANSKY, S. S., & HAFFAJEE, A. D. (2002) · Periodontology 2000 · doi:10.1034/j.1600-0757.2002.280102.x · Cited by 1,273
Slots, J., & Ting, M. (1999) · Periodontology 2000 · doi:10.1111/j.1600-0757.1999.tb00159.x · Cited by 466
Antibiotics in periodontal therapy: advantages and disadvantages*
Slots, J., & Rams, T. E. (1990) · Journal of Clinical Periodontology · doi:10.1111/j.1365-2710.1992.tb01220.x · Cited by 396
Systemic antibiotic therapy in periodontics
Kapoor, A., Malhotra, R., Grover, V., & Grover, D. (2012) · Dental Research Journal · doi:10.4103/1735-3327.104866 · Cited by 381
Metadata
- Authors
- van Winkelhoff, A. J., Rodenburg, J. P., Goené, R. J., Abbas, F., Winkel, E. G., & de Graaff, J.
- Venue
- Journal of Clinical Periodontology
- Publisher
- Wiley
- Published
- 1989-02
- Volume
- 16
- Issue
- 2
- Pages
- 128-131
- ISSN
- 0303-6979 (ISSN-L)
- 1600-051X
- OpenAlex
- W2004825844
- Cited by
- 316
- References
- 1
- FWCI
- 14.24
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- van Winkelhoff, A. J., Rodenburg, J. P., Goené, R. J., Abbas, F., Winkel, E. G., & de Graaff, J. (1989). Metronidazole plus amoxycillin in the treatment of Actinobacillus associated periodontitis. Journal of Clinical Periodontology. https://doi.org/10.1111/j.1600-051x.1989.tb01626.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
