The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Probiotic effects of orally administered Lactobacillus reuteri‐containing tablets on the subgingival and salivary microbiota in patients with gingivitis. A randomized clinical trial
Abstract
Objective: To investigate the effects of an orally administered probiotic on the oral microbiota. Methods: A placebo‐controlled, parallel study was conducted in 40 gingivitis subjects during 8 weeks. Treatment consisted on the administration of a daily tablet, either containing Lactobacillus reuteri or placebo. Unstimulated saliva and subgingival samples were collected and analysed by culture and PCR. Clinical and microbiological outcome variables were compared between and within groups. Results: There were no significant changes between and within the groups in the clinical variables. In saliva, total anaerobic counts after 4 weeks (p = 0.021) and counts of Prevotella intermedia after 8 weeks (p = 0.030), showed reductions in the test group. In subgingival samples, significant reductions in the changes baseline to 4 weeks were observed for P. gingivalis counts (p = 0.008). With PCR, L. reuteri ATCC‐PTA‐5289 was more frequently detected than L. reuteri DSM‐17938. Conclusions: The effect of L. reuteri administered in tablets resulted in a reduction in the number of selected periodontal pathogens in the subgingival microbiota, without an associated clinical impact.
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Citations
Cites
Experimental gingivitis in man
Löe, H., Theilade, E., & Jensen, S. B. (1965) · The Journal of Periodontology · doi:10.1902/jop.1965.36.3.177 · Cited by 3,481 · cited 1×
“Evidence shows that the mechanical removal of supragingival plaque is the most effective tool to prevent gingivitis (Löe et al. 1965), but most individuals do not adequately control plaque accumulation and gingivitis continues to be highly prevalent (Oliver et al.”
BackgroundTursi, A., Brandimarte, G., Papa, A., Giglio, A., Elisei, W., Giorgetti, G. M., Forti, G., Morini, S., Hassan, C., Pistoia, M. A., et al. (2010) · American Journal of Gastroenterology · doi:10.1038/ajg.2010.218 · Cited by 489
Cited by
Role of Lactobacillus reuteri in Human Health and Diseases
Mu, Q., Tavella, V. J., & Luo, X. M. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00757 · Cited by 744
Adhesion mechanisms mediated by probiotics and prebiotics and their potential impact on human health
Monteagudo-Mera, A., Rastall, R. A., Gibson, G. R., Charalampopoulos, D., & Chatzifragkou, A. (2019) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-019-09978-7 · Cited by 743
Nonsurgical and surgical treatment of periodontitis: how many options for one disease?
Graziani, F., Karapetsa, D., Alonso, B., & Herrera, D. (2017) · Periodontology 2000 · doi:10.1111/prd.12201 · Cited by 566
Self-citationTeughels, W., Durukan, A., Ozcelik, O., Pauwels, M., Quirynen, M., & Haytac, M. C. (2013) · Journal of Clinical Periodontology · doi:10.1111/jcpe.12155 · Cited by 329
McFarland, L. V. (2014) · BMJ Open · doi:10.1136/bmjopen-2014-005047 · Cited by 235
Metadata
- Authors
- Iniesta, M., Herrera, D., Montero, E., Zurbriggen, M., Matos, A. R., Marín, M. J., Sánchez‐Beltrán, M. C., Llama‐Palacio, A., & Sanz, M.
- Venue
- Journal of Clinical Periodontology
- Publisher
- Wiley
- Published
- 2012-06-13
- Volume
- 39
- Issue
- 8
- Pages
- 736-744
- ISSN
- 0303-6979 (ISSN-L)
- 1600-051X
- OpenAlex
- W1990961608
- Cited by
- 167
- References
- 2
- FWCI
- 8.35
- Type
- journal article
- Language
- en
- Open access
- closed
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- Iniesta, M., Herrera, D., Montero, E., Zurbriggen, M., Matos, A. R., Marín, M. J., Sánchez‐Beltrán, M. C., Llama‐Palacio, A., & Sanz, M. (2012). Probiotic effects of orally administered Lactobacillus reuteri‐containing tablets on the subgingival and salivary microbiota in patients with gingivitis. A randomized clinical trial. Journal of Clinical Periodontology. https://doi.org/10.1111/j.1600-051x.2012.01914.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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