The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Immunology of Toxoplasma gondii
Abstract
Summary: Toxoplasma gondii is an obligate intracellular parasite. Following oral infection the parasite crosses the intestinal epithelial barrier to disseminate throughout the body and establish latent infection in central nervous tissues. The clinical presentation ranges from asymptomatic to severe neurological disorders in immunocompromised individuals. Since the clinical presentation is diverse and depends, among other factors, on the immune status of the host, in the present review, we introduce parasitological, epidemiological, clinical, and molecular biological aspects of infection with T. gondii to set the stage for an in‐depth discussion of host immune responses. Since immune responses in humans have not been investigated in detail the present review is exclusively referring to immune responses in experimental models of infection. Systemic and local immune responses in different models of infection are discussed, and a separate chapter introduces commonly used animal models of infection.
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Cites
IL-10 inhibits cytokine production by activated macrophages
Fiorentino, D. F., Zlotnik, A., Mosmann, T. R., Howard, M., & O’Garra, A. (1991) · The Journal of Immunology · doi:10.4049/jimmunol.147.11.3815 · Cited by 2,888
IL-23 promotes tumour incidence and growth
Langowski, J. L., Zhang, X., Wu, L., Mattson, J. D., Chen, T., Smith, K., Basham, B., McClanahan, T., Kastelein, R. A., & Oft, M. (2006) · Nature · doi:10.1038/nature04808 · Cited by 1,018
Stumhofer, J. S., Laurence, A., Wilson, E. H., Huang, E., Tato, C. M., Johnson, L. M., Villarino, A. V., Huang, Q., Yoshimura, A., Sehy, D., et al. (2006) · Nature Immunology · doi:10.1038/ni1376 · Cited by 955
Nutter, F. B., Dubey, J. P., Levine, J. F., Breitschwerdt, E. B., Ford, R. B., & Stoskopf, M. K. (2004) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.2004.225.1394 · Cited by 135
Khan, I. A., Murphy, P. M., Casciotti, L., Schwartzman, J. D., Collins, J., Gao, J.-L., & Yeaman, G. R. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.3.1930 · Cited by 88
Metadata
- Authors
- Munoz, M., Liesenfeld, O., & Heimesaat, M. M.
- Venue
- Immunological Reviews
- Publisher
- Wiley
- Published
- 2011-02-23
- Volume
- 240
- Issue
- 1
- Pages
- 269-285
- ISSN
- 0105-2896 (ISSN-L)
- 1600-065X
- OpenAlex
- W1662827845
- Cited by
- 239
- References
- 5
- FWCI
- 2.66
- Type
- journal article
- Language
- en
- Open access
- closed
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- Munoz, M., Liesenfeld, O., & Heimesaat, M. M. (2011). Immunology of Toxoplasma gondii. Immunological Reviews. https://doi.org/10.1111/j.1600-065x.2010.00992.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
