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Review on fluoride, with special emphasis on calcium fluoride mechanisms in caries prevention
Abstract
Low concentrations of fluoride have a beneficial effect on enamel and dentin de‐ and remineralization. After fluoride treatments, such as topical applications, rinses or dentifrices, salivary fluoride concentrations decrease exponentially in a biphasic manner to very low concentrations within a few hours. For treatments to be effective over periods longer than the brushing and the following salivary clearance, fluoride needs to be deposited and slowly released. Calcium fluoride (or like) deposits act in such a way. owing to a surface covering of phosphate and/or proteins, which makes the CaF 2 Jess soluble under in vivo conditions than in a pure form in inorganic solutions. Moreover, due to the phosphate groups on the surface of the calcium fluoride globules, fluoride is assumed to be released with decreasing pH when the phosphate groups are protonated in the dental plaque.
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Citations
Cited by
How to maintain a cariostatic fluoride concentration in the oral environment
Cury, J. A., & Tenuta, L. M. A. (2008) · Advances in Dental Research · doi:10.1177/154407370802000104 · Cited by 101
Laboratory and human studies to estimate anticaries efficacy of fluoride toothpastes
Tenuta, L. M. A., & Cury, J. A. (2013) · Monographs in Oral Science · doi:10.1159/000350479 · Cited by 58
Li, J., Huang, Z., Mei, L., Li, G., & Li, H. (2015) · Caries Research · doi:10.1159/000435894 · Cited by 49
High-fluoride toothpaste: a multicenter randomized controlled trial in adults
Srinivasan, M., Schimmel, M., Riesen, M., Ilgner, A., Wicht, M. J., Warncke, M., Ellwood, R. P., Nitschke, I., Müller, F., & Noack, M. J. (2014) · Community Dentistry and Oral Epidemiology · doi:10.1111/cdoe.12090 · Cited by 40
No calcium-fluoride-like deposits detected in plaque shortly after a sodium fluoride mouthrinse
Vogel, G. L., Tenuta, L. M. A., Schumacher, G. E., & Chow, L. C. (2010) · Caries Research · doi:10.1159/000287239 · Cited by 27
Metadata
- Authors
- ten Cate, J. M.
- Venue
- European Journal of Oral Sciences
- Publisher
- Wiley
- Published
- 1997-10
- Volume
- 105
- Issue
- 5
- Pages
- 461-465
- ISSN
- 0029-845X (ISSN-L)
- 0909-8836
- 1600-0722
- OpenAlex
- W2143173759
- Cited by
- 325
- References
- 0
- FWCI
- 3.11
- Type
- journal article
- Language
- en
- Open access
- closed
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- ten Cate, J. M. (1997). Review on fluoride, with special emphasis on calcium fluoride mechanisms in caries prevention. European Journal of Oral Sciences. https://doi.org/10.1111/j.1600-0722.1997.tb00231.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
