The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Hepatocellular Carcinoma Recurrence and Death Following Living and Deceased Donor Liver Transplantation
Open accessAbstract
We examined mortality and recurrence of hepatocellular carcinoma (HCC) among 106 transplant candidates with cirrhosis and HCC who had a potential living donor evaluated between January 1998 and February 2003 at the nine centers participating in the Adult-to-Adult Living Donor Liver Transplantation Cohort Study (A2ALL). Cox regression models were fitted to compare time from donor evaluation and time from transplant to death or HCC recurrence between 58 living donor liver transplant (LDLT) and 34 deceased donor liver transplant (DDLT) recipients. Mean age and calculated Model for End-Stage Liver Disease (MELD) scores at transplant were similar between LDLT and DDLT recipients (age: 55 vs. 52 years, p = 0.21; MELD: 13 vs. 15, p = 0.08). Relative to DDLT recipients, LDLT recipients had a shorter time from listing to transplant (mean 160 vs. 469 days, p < 0.0001) and a higher rate of HCC recurrence within 3 years than DDLT recipients (29% vs. 0%, p = 0.002), but there was no difference in mortality or the combined outcome of mortality or recurrence. LDLT recipients had lower relative mortality risk than patients who did not undergo LDLT after the center had more experience (p = 0.03). Enthusiasm for LDLT as HCC treatment is dampened by higher HCC recurrence compared to DDLT.
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Cites
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Acute Abdomen: A Rare Case of Ruptured Hepatocellular Carcinoma
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The Statistical Analysis of Failure Time Data
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Cited by
EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma
Galle, P. R., Forner, A., Llovet, J. M., Mazzaferro, V., Piscaglia, F., Raoul, J.-L., Schirmacher, P., & Vilgrain, V. (2018) · Journal of Hepatology · doi:10.1016/j.jhep.2018.03.019 · Cited by 11,406
EASL–EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma
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AASLD Practice Guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma
Singal, A. G., Llovet, J. M., Yarchoan, M., Mehta, N., Heimbach, J. K., Dawson, L. A., Jou, J. H., Kulik, L. M., Agopian, V. G., Marrero, J. A., et al. (2023) · Hepatology · doi:10.1097/hep.0000000000000466 · Cited by 2,052
“[222,223] 226] Because of the ongoing critical organ shortage and recent allocation changes, LDLT is increasing in the United States, with a recent analysis of OPTN data demonstrating excellent post-LT survival in the setting of LDLT for HCC. [ 227,228 ] Use of bridging therapy Given the mandatory…”
Self-citationNew advances in the diagnosis and management of hepatocellular carcinoma
Yang, J. D., & Heimbach, J. K. (2020) · BMJ · doi:10.1136/bmj.m3544 · Cited by 384
Goldberg, D., Mantero, A., Newcomb, C., Delgado, C., Forde, K. A., Kaplan, D. E., John, B., Nuchovich, N., Dominguez, B., Emanuel, E., et al. (2021) · Journal of Hepatology · doi:10.1016/j.jhep.2020.12.021 · Cited by 38
Metadata
- Authors
- Fisher, R. A., Kulik, L. M., Freise, C. E., Lok, A. S. F., Shearon, T. H., Brown, R. S., Ghobrial, R. M., Fair, J. H., Olthoff, K. M., Kam, I., & Berg, C. L.
- Venue
- American Journal of Transplantation
- Publisher
- Elsevier BV
- Published
- 2007-06
- Volume
- 7
- Issue
- 6
- Pages
- 1601-1608
- ISSN
- 1600-6135 (ISSN-L)
- OpenAlex
- W2041235201
- Cited by
- 272
- References
- 17
- FWCI
- 16.82
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: Hepatocellular Carcinoma Recurrence and Death Following Living and Deceased Donor Liver Transplantation. https://app.cochat.ai/papers/10.1111/j.1600-6143.2007.01802.x
- The paper
- Fisher, R. A., Kulik, L. M., Freise, C. E., Lok, A. S. F., Shearon, T. H., Brown, R. S., Ghobrial, R. M., Fair, J. H., Olthoff, K. M., Kam, I., & Berg, C. L. (2007). Hepatocellular Carcinoma Recurrence and Death Following Living and Deceased Donor Liver Transplantation. American Journal of Transplantation. https://doi.org/10.1111/j.1600-6143.2007.01802.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
