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Bridge to Thoracic Organ Transplantation in Patients with Pulmonary Arterial Hypertension Using a Pumpless Lung Assist Device
Open accessAbstract
We describe a novel technique of pumpless extracorporeal life support in four patients with cardiogenic shock due to end-stage pulmonary hypertension (PH) including patients with veno-occlusive disease (PVOD) using a pumpless lung assist device (LAD). The device was connected via the pulmonary arterial main trunk and the left atrium, thereby creating a septostomy-like shunt with the unique addition of gas exchange abilities in parallel to the lung. Using this approach, all four patients were successfully bridged to bilateral lung transplantation and combined heart-lung transplantation, respectively. Although all patients presented in cardiogenic shock, hemodynamic unloading of the right ventricle using the low-resistance LAD stabilized the hemodynamic situation immediately so that no pump support was subsequently required.
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Cited by
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
Galiè, N., Humbert, M., Vachiery, J.-L., Gibbs, S., Lang, I., Torbicki, A., Simonneau, G., Peacock, A., Vonk Noordegraaf, A., Beghetti, M., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehv317 · Cited by 6,931
Self-citationGaliè, N., Humbert, M., Vachiery, J.-L., Gibbs, S., Lang, I., Torbicki, A., Simonneau, G., Peacock, A., Vonk Noordegraaf, A., Beghetti, M., et al. (2015) · European Respiratory Journal · doi:10.1183/13993003.01032-2015 · Cited by 3,172
Self-citationEuropean Resuscitation Council Guidelines for Resuscitation 2010 Section 1. Executive summary
Nolan, J. P., Soar, J., Zideman, D. A., Biarent, D., Bossaert, L. L., Deakin, C., Koster, R. W., Wyllie, J., & Böttiger, B. (2010) · Resuscitation · doi:10.1016/j.resuscitation.2010.08.021 · Cited by 1,375
European Resuscitation Council Guidelines for Resuscitation 2015
Perkins, G. D., Handley, A. J., Koster, R. W., Castrén, M., Smyth, M. A., Olasveengen, T., Monsieurs, K. G., Raffay, V., Gräsner, J.-T., Wenzel, V., et al. (2015) · Resuscitation · doi:10.1016/j.resuscitation.2015.07.015 · Cited by 1,287
2015 ESC/ERS Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension
Galiè, N., Humbert, M., Vachiery, J.-L., Gibbs, S., Lang, I., Torbicki, A., Simonneau, G., Peacock, A., Noordegraaf, A. V., Beghetti, M., et al. (2016) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2016.01.002 · Cited by 357
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Metadata
- Authors
- Strueber, M., Hoeper, M. M., Fischer, S., Cypel, M., Warnecke, G., Gottlieb, J., Pierre, A., Welte, T., Haverich, A., Simon, A. R., & Keshavjee, S.
- Venue
- American Journal of Transplantation
- Publisher
- Elsevier BV
- Published
- 2009-04
- Volume
- 9
- Issue
- 4
- Pages
- 853-857
- ISSN
- 1600-6135 (ISSN-L)
- OpenAlex
- W2049900972
- Cited by
- 219
- References
- 0
- FWCI
- 7.57
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: Bridge to Thoracic Organ Transplantation in Patients with Pulmonary Arterial Hypertension Using a Pumpless Lung Assist Device. https://app.cochat.ai/papers/10.1111/j.1600-6143.2009.02549.x
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- Strueber, M., Hoeper, M. M., Fischer, S., Cypel, M., Warnecke, G., Gottlieb, J., Pierre, A., Welte, T., Haverich, A., Simon, A. R., & Keshavjee, S. (2009). Bridge to Thoracic Organ Transplantation in Patients with Pulmonary Arterial Hypertension Using a Pumpless Lung Assist Device. American Journal of Transplantation. https://doi.org/10.1111/j.1600-6143.2009.02549.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
