The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Local drug delivery for oral mucosal diseases: challenges and opportunities
Open accessAbstract
Oral Diseases (2011) 17 (Suppl. 1), 73–84 There are few topical formulations used for oral medicine applications most of which have been developed for the management of dermatological conditions. As such, numerous obstacles are faced when utilizing these preparations in the oral cavity, namely enzymatic degradation, taste, limited surface area, poor tissue penetration and accidental swallowing. In this review, we discuss common mucosal diseases such as oral cancer, mucositis, vesiculo‐erosive conditions, infections, neuropathic pain and salivary dysfunction, which could benefit from topical delivery systems designed specifically for the oral mucosa, which are capable of sustained release. Each condition requires distinct penetration and drug retention profiles in order to optimize treatment and minimize side effects. Local drug delivery may provide a more targeted and efficient drug‐delivery option than systemic delivery for diseases of the oral mucosa. We identify those mucosal diseases currently being treated, the challenges that must be overcome and the potential of novel therapies. Novel biological therapies such as macromolecular biological drugs, peptides and gene therapy may be of value in the treatment of many chronic oral conditions and thus in oral medicine if their delivery can be optimized.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Dewhirst, F. E., Chen, T., Izard, J., Paster, B. J., Tanner, A. C. R., Yu, W.-H., Lakshmanan, A., & Wade, W. G. (2010) · Journal of Bacteriology · doi:10.1128/jb.00542-10 · Cited by 3,352
Cited by
New developments and opportunities in oral mucosal drug delivery for local and systemic disease
Hearnden, V., Sankar, V., Hull, K., Juras, D. V., Greenberg, M., Kerr, A. R., Lockhart, P. B., Patton, L. L., Porter, S., & Thornhill, M. H. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.02.008 · Cited by 406
Self-citation
Metadata
- Authors
- Sankar, V, Hearnden, V, Hull, K., Juras, D. V., Greenberg, M., Kerr, A., Lockhart, P., Patton, L., Porter, S., & Thornhill, M.
- Venue
- Oral Diseases
- Publisher
- Wiley
- Published
- 2011-03-08
- Volume
- 17
- Issue
- s1
- Pages
- 73-84
- ISSN
- 1354-523X (ISSN-L)
- 1601-0825
- OpenAlex
- W1486369761
- Cited by
- 180
- References
- 1
- FWCI
- 4.85
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Local drug delivery for oral mucosal diseases: challenges and opportunities. https://app.cochat.ai/papers/10.1111/j.1601-0825.2011.01793.x
- The paper
- Sankar, V, Hearnden, V, Hull, K., Juras, D. V., Greenberg, M., Kerr, A., Lockhart, P., Patton, L., Porter, S., & Thornhill, M. (2011). Local drug delivery for oral mucosal diseases: challenges and opportunities. Oral Diseases. https://doi.org/10.1111/j.1601-0825.2011.01793.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
