Life before birth: effects of cortisol on future cardiovascular and metabolic function
Abstract
The concept of fetal programming is an area that is now under rigorous investigation in many laboratories throughout the world. We need to engender a fascination in all segments of society, not just pregnant women, about life in the womb. Conclusion: Everyone needs to understand that improving the condition of the fetus will have personal, social and economic benefits. The time has come to realize that, in a sense, it is not just women who are pregnant but it is the family and the whole of society.
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The brain changes dramatically during fetal development and is vulnerable to environmental insults.
“Because the brain undergoes dramatic changes during fetal development it is vulnerable to environmental insults.”
From High pregnancy anxiety during mid-gestation is associated with decreased gray matter density in 6-9-year-old children. (2010) · cites this paper as Nathanielsz et al., 2003
Cites
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- Authors
- Nathanielsz, P., Berghorn, K., Derks, J., Giussani, D., Docherty, C., Unno, N., Davenport, A., Kutzler, M., Koenen, S., Visser, G., & Nijland, M.
- Affiliations
- University of Cambridge (GB)
- The University of Tokyo (JP)
- Oregon State University (US)
- Venue
- Acta Paediatrica
- Publisher
- Wiley
- Published
- 2003-07
- Volume
- 92
- Issue
- 7
- Pages
- 766-772
- ISSN
- 0365-1436 (ISSN-L)
- 0803-5253
- 1651-2227
- OpenAlex
- W1969180043
- Cited by
- 50
- References
- 15
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 1 · 2020: 5 · 2019: 2 · 2018: 1 · 2017: 3 · 2016: 3 · 2015: 3 · 2014: 4 · 2013: 2 · 2012: 2
- FWCI
- 0.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Paediatrica (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Heart, Lung, and Blood Institute (R01HL055416)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (P01HD021350)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Keywords
- fetal programming, cortisol, antenatal glucocorticoids, cardiovascular function, metabolic function, fetal development, pregnancy
- MeSH terms
- Animals, Cardiovascular System, Female, Fetal Blood, Embryonic and Fetal Development, Fetal Diseases, Heart, Humans, Hydrocortisone, Maternal Welfare, Papio, Perinatology, Pregnancy, Sheep, Socioeconomic Factors, Thyroid Gland, Thyrotropin, Thyroxine, Endothelins
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