The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
Mechanisms for pro matrix metalloproteinase activation
Abstract
The activation of pro matrix metalloproteinases (MMPs) by sequential proteolysis of the propeptide blocking the active site cleft is regarded as one of the key levels of regulation of these proteinases. Potential physiological mechanisms including cell‐associated plasmin generation by urokinase‐like plasminogen activator, or the action of cell surface MT1‐MMPs appear to be involved in the initiation of cascades of pro MMP activation. Gelatinase A, collagenase 3 and gelatinase B may be activated by MT‐MMP based mechanisms, as evidenced by both biochemical and cell based studies. Hence the regulation of MT‐MMPs themselves becomes critical to the determination of MMP activity. This includes activation, assembly at the cell surfaces as TIMP‐2 complexes and subsequent inactivation by proteolysis or TIMP inhibition.
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Cites
Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase
Strongin, A. Y., Collier, I., Bannikov, G., Marmer, B. L., Grant, G. A., & Goldberg, G. I. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.10.5331 · Cited by 1,593
Integrin function: molecular hierarchies of cytoskeletal and signaling molecules.
Miyamoto, S., Teramoto, H., Coso, O. A., Gutkind, J. S., Burbelo, P. D., Akiyama, S. K., & Yamada, K. M. (1995) · The Journal of cell biology · doi:10.1083/jcb.131.3.791 · Cited by 1,203
Ohuchi, E., Imai, K., Fujii, Y., Sato, H., Seiki, M., & Okada, Y. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.4.2446 · Cited by 938
Cellular Mechanisms for Human Procollagenase-3 (MMP-13) Activation
Knäuper, V., Will, H., López-Otin, C., Smith, B., Atkinson, S. J., Stanton, H., Hembry, R. M., & Murphy, G. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.29.17124 · Cited by 747
Self-citationTumor invasion through the human amniotic membrane: Requirement for a proteinase cascade
Mignatti, P., Robbins, E., & Rifkin, D. B. (1986) · Cell · doi:10.1016/0092-8674(86)90613-6 · Cited by 746
Furin-dependent intracellular activation of the human stromelysin-3 zymogen
Pei, D., & Weiss, S. J. (1995) · Nature · doi:10.1038/375244a0 · Cited by 629
Will, H., Atkinson, S. J., Butler, G. S., Smith, B., & Murphy, G. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.29.17119 · Cited by 569
Self-citationButler, G. S., Butler, M. J., Atkinson, S. J., Will, H., Tamura, T., van Westrum, S. S., Crabbe, T., Clements, J., d'Ortho, M.-P., & Murphy, G. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.2.871 · Cited by 470
Self-citationD'ortho, M., Will, H., Atkinson, S., Butler, G., Messent, A., Gavrilovic, J., Smith, B., Timpl, R., Zardi, L., & Murphy, G. (1997) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1997.00751.x · Cited by 443
Self-citationOKADA, Y., MORODOMI, T., ENGHILD, J. J., SUZUKI, K., YASUI, A., NAKANISHI, I., SALVESEN, G., & NAGASE, H. (1990) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1990.tb19462.x · Cited by 429
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Liekens, S., De Clercq, E., & Neyts, J. (2001) · Biochemical Pharmacology · doi:10.1016/s0006-2952(00)00529-3 · Cited by 748
Zhou, Z., Apte, S. S., Soininen, R., Cao, R., Baaklini, G. Y., Rauser, R. W., Wang, J., Cao, Y., & Tryggvason, K. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.060037197 · Cited by 666
Raeber, G. P., Lutolf, M. P., & Hubbell, J. A. (2005) · Biophysical Journal · doi:10.1529/biophysj.104.050682 · Cited by 573
Ovulation: Parallels With Inflammatory Processes
Duffy, D. M., Ko, C., Jo, M., Brannstrom, M., & Curry, T. E. (2019) · Endocrine Reviews · doi:10.1210/er.2018-00075 · Cited by 513
Matrix Metalloproteinases Expressed by Astrocytes Mediate Extracellular Amyloid-β Peptide Catabolism
Yin, K.-J., Cirrito, J. R., Yan, P., Hu, X., Xiao, Q., Pan, X., Bateman, R., Song, H., Hsu, F.-F., Turk, J., et al. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.2085-06.2006 · Cited by 381
Metadata
- Authors
- MURPHY, G., STANTON, H., COWELL, S., BUTLER, G., KNÄUPER, V., ATKINSON, S., & GAVRILOVIC, J.
- Venue
- APMIS
- Publisher
- Wiley
- Published
- 1999-03
- Volume
- 107
- Issue
- 1-6
- Pages
- 38-44
- ISSN
- 0903-4641 (ISSN-L)
- 1600-0463
- OpenAlex
- W2056420432
- Cited by
- 441
- References
- 46
- FWCI
- 13.05
- Type
- journal article
- Language
- en
- Open access
- closed
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