The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
The dipeptidyl peptidase IV family in cancer and cell biology
Open accessAbstract
Of the 600+ known proteases identified to date in mammals, a significant percentage is involved or implicated in pathogenic and cancer processes. The dipeptidyl peptidase IV (DPIV) gene family, comprising four enzyme members [DPIV (EC 3.4.14.5), fibroblast activation protein, DP8 and DP9] and two nonenzyme members [DP6 (DPL1) and DP10 (DPL2)], are interesting in this regard because of their multiple diverse functions, varying patterns of distribution/localization and subtle, but significant, differences in structure/substrate recognition. In addition, their engagement in cell biological processes involves both enzymatic and nonenzymatic capabilities. This article examines, in detail, our current understanding of the biological involvement of this unique enzyme family and their overall potential as therapeutic targets.
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MENTLEIN, R., GALLWITZ, B., & SCHMIDT, W. E. (1993) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1993.tb17986.x · Cited by 1,161
Loeffler, M. (2006) · Journal of Clinical Investigation · doi:10.1172/jci26532 · Cited by 633
Acharya, P. S., Zukas, A., Chandan, V., Katzenstein, A.-L. A., & Puré, E. (2006) · Human Pathology · doi:10.1016/j.humpath.2005.11.020 · Cited by 204
Cited by
The Metabolic Serine Hydrolases and Their Functions in Mammalian Physiology and Disease
Long, J. Z., & Cravatt, B. F. (2011) · Chemical Reviews · doi:10.1021/cr200075y · Cited by 425
Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21
Dunshee, D. R., Bainbridge, T. W., Kljavin, N. M., Zavala-Solorio, J., Schroeder, A. C., Chan, R., Corpuz, R., Wong, M., Zhou, W., Deshmukh, G., et al. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.710582 · Cited by 158
Incretin drugs as modulators of atherosclerosis
Gallego-Colon, E., Wojakowski, W., & Francuz, T. (2018) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2018.09.011 · Cited by 35
Xu, Z., Sinha, A., Pandya, D. N., Schnicker, N. J., & Wadas, T. J. (2025) · RSC Chemical Biology · doi:10.1039/d4cb00267a · Cited by 5
Metadata
- Authors
- Yu, D. M. T., Yao, T., Chowdhury, S., Nadvi, N. A., Osborne, B., Church, W. B., McCaughan, G. W., & Gorrell, M. D.
- Venue
- The FEBS Journal
- Publisher
- Wiley
- Published
- 2010-02-05
- Volume
- 277
- Issue
- 5
- Pages
- 1126-1144
- ISSN
- 1742-464X (ISSN-L)
- 1742-4658
- OpenAlex
- W1577118500
- Cited by
- 183
- References
- 3
- FWCI
- 7.55
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Yu, D. M. T., Yao, T., Chowdhury, S., Nadvi, N. A., Osborne, B., Church, W. B., McCaughan, G. W., & Gorrell, M. D. (2010). The dipeptidyl peptidase IV family in cancer and cell biology. The FEBS Journal. https://doi.org/10.1111/j.1742-4658.2009.07526.x
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