The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
EVALUATION OF PEPPER (CAPSICUM ANNUUM) FOR MANAGEMENT OF DIABETES AND HYPERTENSION
Abstract
Natural α-amylase and α-glucosidase inhibitors from food-grade plants offer an attractive strategy to control postprandial hyperglycemia for type 2 diabetes management. Concurrently associated macrovascular complication of hypertension can be managed by similar extracts by inhibition of angiotensin I-converting enzyme (ACE ). In this study, nine types of pepper were investigated for inhibitory activity against said enzymes. Several pepper extracts had high α-glucosidase inhibitory activity, which was not correlated to total phenolic content and free radical scavenging-linked antioxidant activity. Select extracts such as Green pepper and Long hot pepper had less or no inhibitory effect on the α-amylase activity, which indicates the potential for reduced side effects. Among various water extracts, Yellow, Cubanelle and Red pepper had the highest ACE inhibitory activity. Therefore, combinations of pepper could be screened for dietary management of type 2 diabetes, associated hypertension and microvascular complications linked to oxidative dysfunction, and provide the basis for clinical studies.
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Cites
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
Nishikawa, T., Edelstein, D., Du, X. L., Yamagishi, S.-I., Matsumura, T., Kaneda, Y., Yorek, M. A., Beebe, D., Oates, P. J., Hammes, H.-P., et al. (2000) · Nature · doi:10.1038/35008121 · Cited by 4,277
Hertog, M. G. L. (1995) · Archives of Internal Medicine · doi:10.1001/archinte.1995.00430040053006 · Cited by 1,853
Cited by
Modes of Inhibition ofα-Amylase andα-Glucosidase by Aqueous Extract of Morinda lucida Benth Leaf
Kazeem, M. I., Adamson, J. O., & Ogunwande, I. A. (2013) · BioMed Research International · doi:10.1155/2013/527570 · Cited by 320
Batiha, G. E.-S., Alqahtani, A., Ojo, O. A., Shaheen, H. M., Wasef, L., Elzeiny, M., Ismail, M., Shalaby, M., Murata, T., Zaragoza-Bastida, A., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21155179 · Cited by 259
Agu, K. C., Eluehike, N., Ofeimun, R. O., Abile, D., Ideho, G., Ogedengbe, M. O., Onose, P. O., & Elekofehinti, O. O. (2019) · Clinical Phytoscience · doi:10.1186/s40816-019-0116-0 · Cited by 53
Metadata
- Authors
- KWON, Y.-I., APOSTOLIDIS, E., & SHETTY, K.
- Venue
- Journal of Food Biochemistry
- Publisher
- Hindawi Limited
- Published
- 2007-06
- Volume
- 31
- Issue
- 3
- Pages
- 370-385
- ISSN
- 0145-8884 (ISSN-L)
- 1745-4514
- OpenAlex
- W1972709442
- Cited by
- 158
- References
- 2
- FWCI
- 1.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: EVALUATION OF PEPPER (CAPSICUM ANNUUM) FOR MANAGEMENT OF DIABETES AND HYPERTENSION. https://app.cochat.ai/papers/10.1111/j.1745-4514.2007.00120.x
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- KWON, Y.-I., APOSTOLIDIS, E., & SHETTY, K. (2007). EVALUATION OF PEPPER (CAPSICUM ANNUUM) FOR MANAGEMENT OF DIABETES AND HYPERTENSION. Journal of Food Biochemistry. https://doi.org/10.1111/j.1745-4514.2007.00120.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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