Cited by 50Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology ResearchSmoking Behavior and Cessation

Desensitization of Nicotinic Receptors in the Central Nervous System

FENSTER, C. P., HICKS, J. H., BECKMAN, M. L., COVERNTON, P.J. O., QUICK, M. W., LESTER, R.A. J.·1999·Annals of the New York Academy of Sciences

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Crossref · 10.1111/j.1749-6632.1999.tb11335.x

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1 of 1 references verified0 citation errors · 0 not checkable

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  • α4β2 nAChRs desensitize at nicotine concentrations lower than those required for activation and are mostly desensitized in brains of smokers.

    “These receptors desensitize at nicotine concentrations lower than those required for activation (Fenster et al. 1999) and, as a result, are mostly desensitized in brains of smokers (Brody et al. 2006).”

    From <scp>N</scp> icotine and the adolescent brain (2015) · cites this paper as Fenster et al. 1999

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Authors
FENSTER, C. P., HICKS, J. H., BECKMAN, M. L., COVERNTON, P. J. O., QUICK, M. W., & LESTER, R. A. J.
Affiliations
University of Alabama at Birmingham (US)
Corresponding author
LESTER, R.A. J.
Venue
Annals of the New York Academy of Sciences
Publisher
Wiley
Published
1999-04
Volume
868
Issue
1
Pages
620-623
ISSN
  • 0077-8923 (ISSN-L)
  • 1749-6632
OpenAlex
W2027323167
Cited by
50
References
1
Citations by year
2024: 2 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 2 · 2018: 3 · 2017: 1 · 2016: 2 · 2015: 2 · 2014: 2 · 2013: 2 · 2012: 3
FWCI
0.91
Type
journal article
Language
en
Open access
closed
Locations
  • Annals of the New York Academy of Sciences (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Neurological Disorders and Stroke (NS 31669)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nicotinic Acetylcholine Receptors Study
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
Keywords
nicotinic acetylcholine receptors, receptor desensitization, central nervous system, nicotinic agonists, ligand-gated ion channels
MeSH terms
Animals, Brain, Enzyme Inhibitors, gamma-Aminobutyric Acid, Indoles, Maleimides, Neurons, Nicotine, Oocytes, Protein Kinase C, Receptors, Nicotinic, Xenopus, Patch-Clamp Techniques

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