The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Glial Fibrillary Acidic Protein: Regulation by Hormones, Cytokines, and Growth Factors
Open accessAbstract
Levels of glial fibrillary acidic protein (GFAP), an astrocyte‐specific intermediate filament protein, are altered during development and aging, GFAP also responds dynamically to neurodegenerative lesions. Changes in GFAP expression can occur at both transcriptional and translational levels. Modulators of GFAP expression include steroids, cytokines, and growth factors. GFAP expression also shows brain region‐specific responses to sex steroids and of astrocyte‐neuronal interactions. The 5′‐upstream sequences of rat, mouse, and human are compared for the presence of response elements that are candidates for transcriptional regulation of GFAP. We propose that the regulation of the GFAP gene has evolved a system of controls that allow integrated responses to neuroendocrine and inflammatory modulators.
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Cited by
Middeldorp, J., & Hol, E. M. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.01.005 · Cited by 1,080
Astrocyte reactivity and reactive astrogliosis: costs and benefits
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Astrocyte Pathology in Major Depressive Disorder: Insights from Human Postmortem Brain Tissue
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Glial cell abnormalities in major psychiatric disorders: the evidence and implications
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Sex, glia, and development: Interactions in health and disease
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Self-citationKhundakar, A. A., & Thomas, A. J. (2009) · International Psychogeriatrics · doi:10.1017/s104161020999007x · Cited by 50
Food restriction delays the age-related increase in GFAP mRNA in rat hypothalamus
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Metadata
- Authors
- Laping, N. J., Teter, B., Nichols, N. R., Rozovsky, I., & Finch, C. E.
- Venue
- Brain Pathology
- Publisher
- Wiley
- Published
- 1994-07
- Volume
- 4
- Issue
- 3
- Pages
- 259-275
- ISSN
- 1015-6305 (ISSN-L)
- 1750-3639
- OpenAlex
- W2017200573
- Cited by
- 233
- References
- 4
- FWCI
- 6.27
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
