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NON‐INVASIVE TECHNIQUE FOR OBTAINING FLUORESCENCE EXCITATION AND EMISSION SPECTRA IN VIVO
Abstract
An intensified photodiode array forms the heart of a sensitive spectrophotofluorometry system that permits the rapid and non‐invasive determination of fluorescence emission spectra in the skin of living, non‐anesthetized animals. Using this system, we found it possible to obtain good emission and excitation spectra of the material responsible for the weak red fluorescence that characterizes normal mouse skin, and to follow the biosynthesis and subsequent clearance of protoporphyrin IX in the skin of non‐anesthetized mice that had been given various doses of the porphyrin precursor 5‐aminolevulinic acid.
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Citations
Cited by
Photodynamic therapy with endogenous protoporphyrin
Kennedy, J. C., Pottier, R. H., & Pross, D. C. (1990) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/1011-1344(90)85083-9 · Cited by 1,509
Self-citationKennedy (1992) · doi:10.1016/1011-1344(92)85108-7 · Cited by 1,166
Walter, S., Susanne, S., Simon, W., Herbert, S., Clemens, F., Claudia, G., Alwin, E. G., Rainer, K., & Hans, J. R. (1998) · Neurosurgery · doi:10.1097/00006123-199803000-00017 · Cited by 690
The History of Photodetection and Photodynamic Therapy¶
Ackroyd, R., Kelty, C., Brown, N., & Reed, M. (2007) · Photochemistry and Photobiology · doi:10.1562/0031-8655(2001)0740656thopap2.0.co2 · Cited by 667
Morton, C. A., Brown, S. B., Collins, S., Ibbotson, S., Jenkinson, H., Kurwa, H., Langmack, K., Mckenna, K., Moseley, H., Pearse, A. D., et al. (2002) · British Journal of Dermatology · doi:10.1046/j.1365-2133.2002.04719.x · Cited by 451
Metadata
- Authors
- Pottier, R. H., Chow, Y. F. A., LaPlante, J. ‐., Truscott, T. G., Kennedy, J. C., & Beiner, L. A.
- Venue
- Photochemistry and Photobiology
- Publisher
- Wiley
- Published
- 1986-11
- Volume
- 44
- Issue
- 5
- Pages
- 679-687
- ISSN
- 0031-8655 (ISSN-L)
- 1751-1097
- OpenAlex
- W2107601217
- Cited by
- 176
- References
- 0
- FWCI
- 6.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: NON‐INVASIVE TECHNIQUE FOR OBTAINING FLUORESCENCE EXCITATION AND EMISSION SPECTRA IN VIVO. https://app.cochat.ai/papers/10.1111/j.1751-1097.1986.tb04726.x
- The paper
- Pottier, R. H., Chow, Y. F. A., LaPlante, J. ‐., Truscott, T. G., Kennedy, J. C., & Beiner, L. A. (1986). NON‐INVASIVE TECHNIQUE FOR OBTAINING FLUORESCENCE EXCITATION AND EMISSION SPECTRA IN VIVO. Photochemistry and Photobiology. https://doi.org/10.1111/j.1751-1097.1986.tb04726.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
