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Cited by 543

The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.

Gold Nanorods as Contrast Agents for Biological Imaging: Optical Properties, Surface Conjugation and Photothermal Effects†

Open access
Tong, Ling, Wei, Qingshan, Wei, Alexander, Cheng, Ji‐Xin·2009·Photochemistry and Photobiology

Abstract

Gold nanorods (NRs) have plasmon‐resonant absorption and scattering in the near‐infrared (NIR) region, making them attractive probes for in vitro and in vivo imaging. In the cellular environment, NRs can provide scattering contrast for darkfield microscopy, or emit a strong two‐photon luminescence due to plasmon‐enhanced two‐photon absorption. NRs have also been employed in biomedical imaging modalities such as optical coherence tomography or photoacoustic tomography. Careful control over surface chemistry enhances the capacity of NRs as biological imaging agents by enabling cell‐specific targeting, and by increasing their dispersion stability and circulation lifetimes. NRs can also efficiently convert optical energy into heat, and inflict localized damage to tumor cells. Laser‐induced heating of NRs can disrupt cell membrane integrity and homeostasis, resulting in Ca 2+ influx and the depolymerization of the intracellular actin network. The combination of plasmon‐resonant optical properties, intense local photothermal effects and robust surface chemistry render gold NRs as promising theragnostic agents.

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Crossref · 10.1111/j.1751-1097.2008.00507.x

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Metadata

Authors
Tong, L., Wei, Q., Wei, A., & Cheng, J.
Venue
Photochemistry and Photobiology
Publisher
Wiley
Published
2009-01
Volume
85
Issue
1
Pages
21-32
ISSN
  • 0031-8655 (ISSN-L)
  • 1751-1097
OpenAlex
W2167737820
Cited by
543
References
88
FWCI
19.56
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Gold Nanorods as Contrast Agents for Biological Imaging: Optical Properties, Surface Conjugation and Photothermal Effects†. https://app.cochat.ai/papers/10.1111/j.1751-1097.2008.00507.x
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Tong, L., Wei, Q., Wei, A., & Cheng, J. (2009). Gold Nanorods as Contrast Agents for Biological Imaging: Optical Properties, Surface Conjugation and Photothermal Effects†. Photochemistry and Photobiology. https://doi.org/10.1111/j.1751-1097.2008.00507.x

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.