Sex differences in short-term heart rate variability in patients with newly diagnosed essential hypertension
Open accessAbstract
The authors report the results of the analysis of heart rate variability (HRV) indices during 5 minutes of supine rest and 5 minutes of standing and conventional indices of autonomic function in 69 men and 51 women with untreated newly diagnosed hypertension matched for body mass index and resting blood pressure. Mean RR interval, standard deviation of normal-to-normal RR intervals, low-frequency RR spectral power, HRV during deep breathing at 6 breaths per minute, and the 30:15 ratio (maximum RR interval 30th beat/minimum RR interval 15th beat) were significantly lower in women (P=.01, .02, .001, .04, .01, respectively) compared with men. Low frequency RR in normalized units was lower in women in the supine position alone (P=.03). HRV was significantly lower in women with untreated newly diagnosed hypertension compared with men. The authors interpret these results as indicating an increase in baseline cardiac sympathovagal balance in female hypertensive patients.
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HF decreases with male gender.
“Finally, in line with the literature, we demonstrated a decrease in both LF and HF with age [95] and the male gender [96].”
From Heart rate variability in type 2 diabetes mellitus: A systematic review and meta–analysis (2018) · cites this paper as [96]
LF decreases with male gender.
“Finally, in line with the literature, we demonstrated a decrease in both LF and HF with age [95] and the male gender [96].”
From Heart rate variability in type 2 diabetes mellitus: A systematic review and meta–analysis (2018) · cites this paper as [96]
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Heart rate variability in type 2 diabetes mellitus: A systematic review and meta–analysis
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- Authors
- Pavithran, P., Madanmohan, T., & Nandeesha, H.
- Affiliations
- Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
- Venue
- The Journal of Clinical Hypertension
- Publisher
- Wiley
- Published
- 2008-12
- Volume
- 10
- Issue
- 12
- Pages
- 904-910
- ISSN
- 1524-6175 (ISSN-L)
- 1751-7176
- PMC
- PMC8673378
- OpenAlex
- W1990359346
- Cited by
- 13
- References
- 29
- Citations by year
- 2025: 1 · 2023: 2 · 2021: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 2 · 2013: 2 · 2012: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Hypertension (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Indian Council of Medical Research
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Keywords
- heart rate variability, sex differences, essential hypertension, newly diagnosed hypertension, autonomic function, sympathovagal balance, RR interval, deep breathing, supine rest, standing posture
- MeSH terms
- Anthropometry, Antihypertensive Agents, Blood Pressure, Female, Heart Function Tests, Heart Rate, Humans, Hypertension, India, Male, Middle Aged, Posture, Prospective Studies, Rest, Sex Characteristics, Sex Factors, Time Factors, Body Mass Index, Supine Position
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