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Quest for the Molecular Mechanism of Chromium Action and Its Relationship to Diabetes

Vincent, John B.·2009·Nutrition Reviews

Abstract

Despite forty years of research on the potential role of chromium in carbohydrate and lipid metabolism, significant progress has only recently been made regarding the mode of action of chromium at a molecular level. The oligopeptide low-molecular-weight chromium-binding substance (LMWCr) may function as part of a novel insulin-signaling autoamplification mechanism. The proposed mechanism of action also sheds some light on the potential of chromium-containing compounds as nutritional supplements or in the treatment of adult-onset diabetes and other conditions. The potential relationship between the results of recent studies on diabetic patients and the proposed mode of action of LMWCr are discussed.

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Metadata

Authors
Vincent, J. B.
Venue
Nutrition Reviews
Published
2009-04-27
Volume
58
Issue
3
Pages
67-72
ISSN
  • 0029-6643 (ISSN-L)
  • 1753-4887
OpenAlex
W2124907205
Cited by
214
References
0
FWCI
8.19
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Quest for the Molecular Mechanism of Chromium Action and Its Relationship to Diabetes. https://app.cochat.ai/papers/10.1111/j.1753-4887.2000.tb01841.x
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Vincent, J. B. (2009). Quest for the Molecular Mechanism of Chromium Action and Its Relationship to Diabetes. Nutrition Reviews. https://doi.org/10.1111/j.1753-4887.2000.tb01841.x

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