Dental conditions in patients with bipolar disorder on long‐term lithium maintenance therapy
Abstract
Bipolar disorder (manic depressive disease) affects 1% of the United States population. These persons suffer from episodes of extreme elation followed by long periods of depression. Dental screening examinations of 40 patients consecutively admitted to the medical center with this diagnosis were performed. Poor oral hygiene, accumulations of supragingival and subgingival calculus, extensive dental caries, and numerous missing teeth were commonly identified. The majority of patients with bipolar disorder are treated with lithium carbonate. The physiological effects of lithium, and its interaction with drugs used in dentistry are reviewed, and disease‐specific modifications in dental treatment are recommended.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Dental health has been consistently found to be poor in people with SMI.
“Dental health has been consistently found to be poor in people with SMI (562-573).”
From Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care (2011) · cites this paper as [568]
Cites
Diagnostic and Statistical Manual of Mental Disorders
&NA; (1988) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-198802020-00022 · Cited by 12,603 · see citing works
Comprehensive Textbook of Psychiatry
Freedman, A. M., & Kaplan, H. I. (1967) · The American Journal of the Medical Sciences · doi:10.1097/00000441-196712000-00052 · Cited by 3,825 · see citing works
The Pharmacological Basis of Therapeutics
Woog, J. J. (1986) · Archives of Ophthalmology · doi:10.1001/archopht.1986.01050150036019 · Cited by 1,539 · see citing works
The Pharmacological Basis of Therapeutics, 7th ed
Egle, J. L. (1986) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600750839 · Cited by 927 · see citing works
Comprehensive Textbook of Psychiatry.
GRINKER, R. R. (1967) · Archives of General Psychiatry · doi:10.1001/archpsyc.1967.01730290127021 · Cited by 403 · see citing works
Renal function after long-term treatment with lithium.
HULLIN, R. P., Coley, V. P., Birch, N. J., et al. (1979) · BMJ · doi:10.1136/bmj.1.6176.1457 · Cited by 99 · see citing works
Self-citationA Manic Depressive Psychotic with a Persistent Forty-eight Hour Cycle
Jenner, F. A., GJESSING, L. R., Cox, J. R., Davies-Jones, A., HULLIN, R. P., & Hanna, S. M. (1967) · The British Journal of Psychiatry · doi:10.1192/bjp.113.501.895 · Cited by 93 · see citing works
Singer, P. D. I. (1981) · Kidney International · doi:10.1038/ki.1981.28 · Cited by 72 · see citing works
Salivary secretion and dental caries experience in drug addicts
di Cugno, F., Perec, C. J., & Tocci, A. A. (1981) · Archives of Oral Biology · doi:10.1016/0003-9969(81)90031-5 · Cited by 63 · see citing works
Scott, J., Burns, J. E., & Flower, E. A. (1988) · Journal of Clinical Pathology · doi:10.1136/jcp.41.8.837 · Cited by 60 · see citing works
Birch, N. J. (1989) · International Clinical Psychopharmacology · doi:10.1097/00004850-198904000-00008 · Cited by 53 · see citing works
Self-citationPatterns of Salivary Flow in Depressive Illness and During Treatment
Palmai, G., Blackwell, B., Maxwell, A. E., & Morgenstern, F. (1967) · The British Journal of Psychiatry · doi:10.1192/bjp.113.504.1297 · Cited by 53 · see citing works
Salivation in affective disorders
Bolwig, T. G., & Rafaelsen, O. J. (1972) · Psychological Medicine · doi:10.1017/s0033291700042525 · Cited by 44 · see citing works
Lichenoid stomatitis associated with lithium carbonate
Hogan, D. J., Murphy, F., Burgess, W. R., et al. (1985) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(85)70166-1 · Cited by 39 · see citing works
Animal models used in prediction of antidepressant effects in man.
Remick, R. A., Blasberg, B., Patterson, B. D., Carmichael, R. P., & Miles, J. E. (1983) · PubMed · Cited by 35 · see citing works
Drugs, Dry Mouth, and Dental Disease
Stevens, J. B., & Wilkinson, E. G. (1971) · Psychosomatics · doi:10.1016/s0033-3182(71)71491-1 · Cited by 32 · see citing works
Salivary lithium concentration—A tool for monitoring psychiatric patients
Ben‐Aryeh, H., Naon, H., Szargel, R., Gutman, D., & Hefetz, A. (1980) · Oral Surgery Oral Medicine Oral Pathology · doi:10.1016/0030-4220(80)90198-x · Cited by 25 · see citing works
Alcoholism and dental management
Friedlander, A. H., Mills, M. J., & Gorelick, D. A. (1987) · Oral Surgery Oral Medicine Oral Pathology · doi:10.1016/0030-4220(87)90338-0 · Cited by 22 · see citing works
Self-citationRenal toxicity of lithium and its implications.
DePaulo, J. R., Correa, E. I., & SAPIR, D. G. (1981) · PubMed · Cited by 21 · see citing works
Contact stomatitis and lithium carbonate tablets
Muñiz, C. E. (1978) · JAMA · doi:10.1001/jama.239.26.2759c · Cited by 16 · see citing works
Nonspecific stomatitis due to lithium therapy
Nathan, E. A. B., Brenner, S., & Horowitz, I. (1985) · American Journal of Psychiatry · doi:10.1176/ajp.142.9.1126a · Cited by 13 · see citing works
The dental management of depressed patients
Friedlander, A. H., & Brill, N. Q. (1987) · Special Care in Dentistry · doi:10.1111/j.1754-4505.1987.tb00603.x · Cited by 7 · see citing works
Self-citationLazarus, J. H., Fell, G. S., Robertson, J. W. K., et al. (1973) · Archives of Oral Biology · doi:10.1016/0003-9969(73)90155-6 · Cited by 7 · see citing works
Cyclic Sialorrhea Unrelated to Lithium in a Patient With Bipolar Affective Disorder
ALIAS, A. G., Shen, W. W., & Parwatikar, S. D. (1983) · American Journal of Psychiatry · doi:10.1176/ajp.140.11.1538-b · Cited by 5 · see citing works
Curzon, M. E. J., Richardson, D., & Featherstone, J. D. B. (1986) · Journal of Dental Research · doi:10.1177/00220345860650030901 · Cited by 5 · see citing works
The effect of lithium and other antidepressant medications on the autonomic nervous system.
Ds, S. (1973) · PubMed · Cited by 5 · see citing works
Salivary Gland Involvement in Systemic Diseases
Ritter, F. N. (1977) · Otolaryngologic Clinics of North America · doi:10.1016/s0030-6665(20)32623-2 · Cited by 5 · see citing works
Effect of Lithium Upon Plaque and Gingivitis in the Beagle Dog
McDonald, J. L., Schemehorn, B. R., & Stookey, G. K. (1978) · Journal of Dental Research · doi:10.1177/00220345780570031201 · Cited by 2 · see citing works
Book Reviews : Depression and Mania: Modern Lithium Therapy
Healy, D. (1987) · Journal of Psychopharmacology · doi:10.1177/026988118700100409 · Cited by 1 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
DE HERT, M., CORRELL, C. U., BOBES, J., CETKOVICH‐BAKMAS, M., COHEN, D., ASAI, I., DETRAUX, J., GAUTAM, S., MÖLLER, H., NDETEI, D. M., et al. (2011) · World Psychiatry · doi:10.1002/j.2051-5545.2011.tb00014.x · Cited by 2,488 · see citing works
Hede, B. (1995) · Acta Odontologica Scandinavica · doi:10.3109/00016359509005942 · Cited by 56 · see citing works
- Authors
- Friedlander, A. H., & Birch, N. J.
- Affiliations
- University of California, Los Angeles (US)
- Venue
- Special Care in Dentistry
- Publisher
- Wiley
- Published
- 1990-09
- Volume
- 10
- Issue
- 5
- Pages
- 148-151
- ISSN
- 0275-1879 (ISSN-L)
- 1754-4505
- OpenAlex
- W1979311112
- Cited by
- 30
- References
- 29
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 1 · 2020: 1 · 2019: 2 · 2018: 2 · 2016: 2 · 2015: 3 · 2014: 1 · 2012: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Special Care in Dentistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Dentistry › Periodontics › Dental Health and Care Utilization
- Health Sciences › Dentistry › Periodontics › Oral Health Pathology and Treatment
- Keywords
- bipolar disorder, lithium carbonate, oral health, dental caries, poor oral hygiene, tooth loss, psychiatric patients
- MeSH terms
- Adult, Antidepressive Agents, Bipolar Disorder, Dental Calculus, Dental Caries, DMF Index, Female, Gingivitis, Humans, Jaw, Edentulous, Jaw, Edentulous, Partially, Male, Middle Aged, Oral Hygiene, Tooth Diseases, Xerostomia, Tooth Loss, Lithium Carbonate, Dental Care for Chronically Ill, Antimanic Agents
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review