The mechanisms relating to increases in plasma enzymes and isoenzymes in diseases of animals
Abstract
Changes in plasma or serum enzymes and isoenzymes are useful indicators of tissue damage in many diseases. Enzyme increases are usually related to leakage of enzymes from damaged cells. The amount of increase depends on factors such as the concentration of enzyme in the cells, the rate of leakage of enzyme from cells and the rate of clearance of enzyme from plasma. There are important species variations in the tissue concentrations and plasma clearance rates of enzymes and isoenzymes.
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Creatine kinase is often referred to as an indicator of tissue damage, poor muscular tissue reperfusion, hypoxia, and fatigue, and may be an indicator of tissue damage in diseased animals.
“Creatine kinase is often referred to as an indicator of tissue damage, poor muscular tissue reperfusion, hypoxia, and fatigue, and may be an indicator of tissue damage in diseased animals”
From A randomized controlled trial investigating the effect of transport duration and age at transport on surplus dairy calves: Part II. Impact on hematological variables. (2023) · cites this paper as Boyd, 1983
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- Authors
- Boyd, J. W.
- Affiliations
- Virginia–Maryland College of Veterinary Medicine (US)
- Corresponding author
- Boyd, J.W.
- Venue
- Veterinary Clinical Pathology
- Publisher
- Wiley
- Published
- 1983-04
- Volume
- 12
- Issue
- 2
- Pages
- 9-24
- ISSN
- 0275-6382 (ISSN-L)
- 1939-165X
- OpenAlex
- W2071761385
- Cited by
- 184
- References
- 84
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 8 · 2023: 9 · 2022: 9 · 2021: 7 · 2020: 9 · 2019: 7 · 2018: 6 · 2017: 7 · 2016: 5 · 2015: 4 · 2014: 5 · 2013: 12 · 2012: 9
- FWCI
- 1.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Veterinary Clinical Pathology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Veterinary › Small Animals › Veterinary Medicine and Surgery
- Health Sciences › Veterinary › Small Animals › Animal health and immunology
- Health Sciences › Medicine › Physiology › Clinical Laboratory Practices and Quality Control
- Keywords
- plasma enzymes, isozymes, serum enzymes, tissue damage, enzyme leakage, enzyme clearance, species variation, animal diseases, diagnostic biomarkers
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