The DOI matches its Crossref record.
Menthol and Related Cooling Compounds
Abstract
Summary: Menthol and related cooling compounds such as ‘coolant agent 10’, are widely used in products ranging from common cold medications to toothpastes, confectionery, cosmetics and pesticides. The review brings together a range of information on production and chemistry of menthol, and its metabolism, mechanism of action, structure-activity relationships, pharmacology and toxicology. In particular, the coolant action and carminative actions of menthol are discussed in terms of actions on calcium conductance in sensory nerves and smooth muscle. The actions of menthol on the nose, respiratory reflexes, oral cavity, skin and gastrointestinal tract are reviewed.
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Citations
Cited by
Trp ion channels and temperature sensation
Dhaka, A., Viswanath, V., & Patapoutian, A. (2006) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.112958 · Cited by 782
TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain
Liu, B., Fan, L., Balakrishna, S., Sui, A., Morris, J. B., & Jordt, S.-E. (2013) · Pain · doi:10.1016/j.pain.2013.06.043 · Cited by 319
Deepika, Juneja, S., & Pandey, S. (2022) · Journal of Chemical & Engineering Data · doi:10.1021/acs.jced.2c00495 · Cited by 70
Metadata
- Authors
- Eccles, R.
- Venue
- Journal of Pharmacy and Pharmacology
- Publisher
- Oxford University Press (OUP)
- Published
- 1994-08-01
- Volume
- 46
- Issue
- 8
- Pages
- 618-630
- ISSN
- 0022-3573 (ISSN-L)
- 2042-7158
- OpenAlex
- W2064124980
- Cited by
- 503
- References
- 0
- FWCI
- 1.99
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
