Cited by 126Atrial Fibrillation Management and OutcomesCardiac Arrhythmias and TreatmentsCardiac pacing and defibrillation studies

Cryoballoon versus RF ablation in paroxysmal atrial fibrillation: results from the German Ablation Registry

SCHMIDT, MARTIN, DORWARTH, UWE, ANDRESEN, DIETRICH, BRACHMANN, JOHANNES, KUCK, KARL‐HEINZ, KUNISS, MALTE, LEWALTER, THORSTEN, SPITZER, STEFAN +4 more·2014·Journal of Cardiovascular Electrophysiology

Abstract

BACKGROUND: Catheter ablation is used extensively with curative intention in atrial fibrillation. Radiofrequency ablation has long been a standard of care, while cryoballoon technology has emerged as a feasible approach with promising results. Prospective multicenter registry data referring to both ablation technologies in AF ablation therapy are lacking. METHODS: Between January 2007 and August 2011, a total of 3,775 consecutive patients with symptomatic paroxysmal AF who underwent PV ablation in their respective centers were enrolled. The cohort was divided into 2 groups according to the ablation energy source used: cryoballoon ablation (group 1, n = 905 [24.0%], median age 63 years, 64.3% men) and RF ablation (group 2, n = 2870 [76.0%], median age 63 years, 62.7% men). Comorbidities and baseline clinical characteristics were similar in both groups. RESULTS: Acute success rate was similar in both groups (97.5% in cryo vs 97.6% in RF; P = 0.81). Procedure times were similar, ablation and fluoroscopy times were higher in cryoballoon when compared to RF ablation. Overall complication rate was similar in cryo- (4.6%) and RF-ablation (4.6%; P = 1.0). Phrenic nerve palsy was more often in cryo versus RF ablation (2.1% in cryo vs 0.0% in RF; P < 0.001). Other complications were more common in RF compared to cryoablation (4.6% in RF vs 2.7% in cryo; P < 0.05). CONCLUSION: RF ablation is the most widespread ablation method in Germany, but use of cryoballoon increased significantly. Procedure times were similar, but ablation and fluoroscopy times were longer in cryoballoon ablation. No significant differences were found in terms of acute success and overall complication rate.

Integrity signals

Registry

Crossref · 10.1111/jce.12267

Cites

33 of 33 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Pulmonary vein isolation is achievable by point-by-point radiofrequency ablation, linear lesions encircling the pulmonary veins, or cryoballoon ablation, with similar outcomes.

    “achievable by point-by-point radiofrequency ablation, linear lesions encircling the pulmonary veins, or cryoballoon ablation, with similar outcomes.[732][733][734]”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
SCHMIDT, M., DORWARTH, U., ANDRESEN, D., BRACHMANN, J., KUCK, K., KUNISS, M., LEWALTER, T., SPITZER, S., WILLEMS, S., SENGES, J., JÜNGER, C., & HOFFMANN, E.
Affiliations
  • München Klinik Bogenhausen (DE)
  • Vivantes Klinikum (DE)
  • Klinikum Coburg (DE)
  • Department of Cardiology Asklepios Klinik St. Georg Hamburg Germany
  • Kerckhoff Klinik (DE)
  • TUM Klinikum (DE)
  • Praxisklinik Herz und Gefäße Dresden Germany
  • Universität Hamburg (DE)
  • Stiftung Institut für Herzinfarktforschung (DE)
Corresponding author
SCHMIDT, MARTIN
Venue
Journal of Cardiovascular Electrophysiology
Publisher
Wiley
Published
2013-10-17
Volume
25
Issue
1
Pages
1-7
ISSN
  • 1045-3873 (ISSN-L)
  • 1540-8167
OpenAlex
W1813436278
Cited by
126
References
33
Citations by year
2026: 1 · 2025: 4 · 2024: 5 · 2023: 2 · 2022: 6 · 2021: 6 · 2020: 10 · 2019: 5 · 2018: 10 · 2017: 12 · 2016: 22 · 2015: 21 · 2014: 20 · 2013: 2
FWCI
14.72
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Cardiovascular Electrophysiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
Stiftung Institut für Herzinfarktforschung Ludwigshafen, Germany
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Keywords
paroxysmal atrial fibrillation, cryoballoon ablation, radiofrequency ablation, catheter ablation, pulmonary vein ablation, procedural success, procedural complications, phrenic nerve palsy, fluoroscopy time
MeSH terms
Aged, Atrial Fibrillation, Cryosurgery, Female, Germany, Humans, Male, Middle Aged, Prospective Studies, Registries, Cohort Studies, Catheter Ablation

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review