The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.
Immunogenic cell death in cancer therapy: Present and emerging inducers
Open accessAbstract
In the tumour microenvironment (TME), immunogenic cell death (ICD) plays a major role in stimulating the dysfunctional antitumour immune system. Chronic exposure of damage‐associated molecular patterns (DAMPs) attracts receptors and ligands on dendritic cells (DCs) and activates immature DCs to transition to a mature phenotype, which promotes the processing of phagocytic cargo in DCs and accelerates the engulfment of antigenic components by DCs. Consequently, via antigen presentation, DCs stimulate specific T cell responses that kill more cancer cells. The induction of ICD eventually results in long‐lasting protective antitumour immunity. Through the exploration of ICD inducers, recent studies have shown that there are many novel modalities with the ability to induce immunogenic cancer cell death. In this review, we mainly discussed and summarized the emerging methods for inducing immunogenic cancer cell death. Concepts and molecular mechanisms relevant to antitumour effects of ICD are also briefly discussed.
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Current Challenges and Opportunities of Photodynamic Therapy against Cancer
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Jiao, X., Sun, L., Zhang, W., Ren, J., Zhang, L., Cao, Y., Xu, Z., Kang, Y., & Xue, P. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120787 · Cited by 127
Metadata
- Authors
- Zhou, J., Wang, G., Chen, Y., Wang, H., Hua, Y., & Cai, Z.
- Venue
- Journal of Cellular and Molecular Medicine
- Publisher
- Wiley
- Published
- 2019-06-18
- Volume
- 23
- Issue
- 8
- Pages
- 4854-4865
- ISSN
- 1582-1838 (ISSN-L)
- 1582-4934
- OpenAlex
- W2950071015
- Cited by
- 719
- References
- 83
- FWCI
- 25.07
- Type
- journal article
- Language
- en
- Open access
- gold
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- Zhou, J., Wang, G., Chen, Y., Wang, H., Hua, Y., & Cai, Z. (2019). Immunogenic cell death in cancer therapy: Present and emerging inducers. Journal of Cellular and Molecular Medicine. https://doi.org/10.1111/jcmm.14356
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