The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Bone grafts: which is the ideal biomaterial?
Open accessAbstract
Bovine xenograft materials, followed by synthetic biomaterials, which unfortunately still lack documented predictability and clinical performance, dominate the market for the cranio‐maxillofacial area. In Europe, new stringent regulations are expected to further limit the allograft market in the future. Aim: Within this narrative review, we discuss possible future biomaterials for bone replacement. Scientific Rationale for Study: Although the bone graft (BG) literature is overflooded, only a handful of new BG substitutes are clinically available. Laboratory studies tend to focus on advanced production methods and novel biomaterial features, which can be costly to produce. Practical Implications: In this review, we ask why such a limited number of BG s are clinically available when compared to extensive laboratory studies. We also discuss what features are needed for an ideal BG. Results: We have identified the key properties of current bone substitutes and have provided important information to guide clinical decision‐making and generate new perspectives on bone substitutes. Our results indicated that different mechanical and biological properties are needed despite each having a broad spectrum of variations. Conclusions: We foresee bone replacement composite materials with higher levels of bioactivity, providing an appropriate balance between bioabsorption and volume maintenance for achieving ideal bone remodelling.
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Cites
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Bone Grafts and Substitutes in Dentistry: A Review of Current Trends and Developments
Zhao, R., Yang, R., Cooper, P. R., Khurshid, Z., Shavandi, A., & Ratnayake, J. (2021) · Molecules · doi:10.3390/molecules26103007 · Cited by 641
Inorganic nanomaterials with rapid clearance for biomedical applications
Wang, X., Zhong, X., Li, J., Liu, Z., & Cheng, L. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00461h · Cited by 509
Bone Tissue Engineering Scaffolds: Function of Multi‐Material Hierarchically Structured Scaffolds
Koushik, T. M., Miller, C. M., & Antunes, E. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202202766 · Cited by 359
Rupp, M., Klute, L., Baertl, S., Walter, N., Mannala, G., Frank, L., Pfeifer, C., Alt, V., & Kerschbaum, M. (2022) · Journal of Biomedical Materials Research Part B: Applied Biomaterials · doi:10.1002/jbm.b.34911 · Cited by 58
Han, S. H., Cha, M., Jin, Y.-Z., Lee, K.-M., & Lee, J. H. (2021) · Biomedical Materials · doi:10.1088/1748-605x/aba879 · Cited by 53
Metadata
- Authors
- Haugen, H. J., Lyngstadaas, S. P., Rossi, F., & Perale, G.
- Venue
- Journal of Clinical Periodontology
- Publisher
- Wiley
- Published
- 2019-06
- Volume
- 46
- Issue
- S21
- Pages
- 92-102
- ISSN
- 0303-6979 (ISSN-L)
- 1600-051X
- OpenAlex
- W2909370897
- Cited by
- 573
- References
- 84
- FWCI
- 18.41
- Type
- journal article
- Language
- en
- Open access
- green
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- Haugen, H. J., Lyngstadaas, S. P., Rossi, F., & Perale, G. (2019). Bone grafts: which is the ideal biomaterial? Journal of Clinical Periodontology. https://doi.org/10.1111/jcpe.13058
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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