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Cited by 573

The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.

Bone grafts: which is the ideal biomaterial?

Open access
Haugen, Håvard Jostein, Lyngstadaas, Ståle Petter, Rossi, Filippo, Perale, Giuseppe·2019·Journal of Clinical Periodontology

Abstract

Bovine xenograft materials, followed by synthetic biomaterials, which unfortunately still lack documented predictability and clinical performance, dominate the market for the cranio‐maxillofacial area. In Europe, new stringent regulations are expected to further limit the allograft market in the future. Aim: Within this narrative review, we discuss possible future biomaterials for bone replacement. Scientific Rationale for Study: Although the bone graft (BG) literature is overflooded, only a handful of new BG substitutes are clinically available. Laboratory studies tend to focus on advanced production methods and novel biomaterial features, which can be costly to produce. Practical Implications: In this review, we ask why such a limited number of BG s are clinically available when compared to extensive laboratory studies. We also discuss what features are needed for an ideal BG. Results: We have identified the key properties of current bone substitutes and have provided important information to guide clinical decision‐making and generate new perspectives on bone substitutes. Our results indicated that different mechanical and biological properties are needed despite each having a broad spectrum of variations. Conclusions: We foresee bone replacement composite materials with higher levels of bioactivity, providing an appropriate balance between bioabsorption and volume maintenance for achieving ideal bone remodelling.

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Crossref · 10.1111/jcpe.13058

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Metadata

Authors
Haugen, H. J., Lyngstadaas, S. P., Rossi, F., & Perale, G.
Venue
Journal of Clinical Periodontology
Publisher
Wiley
Published
2019-06
Volume
46
Issue
S21
Pages
92-102
ISSN
  • 0303-6979 (ISSN-L)
  • 1600-051X
OpenAlex
W2909370897
Cited by
573
References
84
FWCI
18.41
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Bone grafts: which is the ideal biomaterial? https://app.cochat.ai/papers/10.1111/jcpe.13058
The paper
Haugen, H. J., Lyngstadaas, S. P., Rossi, F., & Perale, G. (2019). Bone grafts: which is the ideal biomaterial? Journal of Clinical Periodontology. https://doi.org/10.1111/jcpe.13058

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.