The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Serum homocysteine level and gestational diabetes mellitus: A meta‐analysis
Open accessAbstract
Aims/Introduction: Homocysteine levels during pregnancy in women with gestational diabetes mellitus (GDM) have been studied; however, it remains unclear whether hyperhomocysteinemia is a useful predictor of insulin resistance. The present study aimed to evaluate the relationship between homocysteine level and GDM. Materials and Methods: PubMed, Elsevier, Web of Science and CNKI were searched for relevant studies published up to January 2015. Manual searches of references of the relevant original studies were carried out. Meta‐analysis was used to assessed the relationship between homocysteine level and GDM using the stata 12.0 software. Results: Homocysteine levels were significantly elevated in women with GDM compared with those without GDM (weighted mean difference 0.77, 95% confidence interval 0.44–1.10). This evidence was more consistent during the second trimester measurement of homocysteine (weighted mean difference 0.95, 95% confidence interval 0.67–1.23) and for women aged older than 30 years (weighted mean difference 0.90, 95% confidence interval 0.63–1.17). Conclusions: The present meta‐analysis shows that homocysteine level is significantly elevated among women with GDM compared with women with normal glucose tolerance, and this finding persists more during the second trimester.
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A recent meta-analysis reported significantly higher homocysteine concentrations among women with GDM as compared with those without GDM.
“The authors reported significantly higher homocysteine concentrations among women with GDM as compared with those without GDM [146].”
From The Pathophysiology of Gestational Diabetes Mellitus (2018) · cites this paper as [146]
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Standards of Medical Care in Diabetes—2009
American Diabetes Association (2009) · Diabetes Care · doi:10.2337/dc09-s013 · Cited by 2,167
Maternal Age and Prevalence of Gestational Diabetes Mellitus
Lao, T. T., Ho, L.-F., Chan, B. C. P., & Leung, W.-C. (2006) · Diabetes Care · doi:10.2337/diacare.29.04.06.dc05-2568 · Cited by 138
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The Pathophysiology of Gestational Diabetes Mellitus
Plows, J. F., Stanley, J. L., Baker, P. N., Reynolds, C. M., & Vickers, M. H. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19113342 · Cited by 1,874
“The authors reported significantly higher homocysteine concentrations among women with GDM as compared with those without GDM [146].”
Result
Metadata
- Authors
- Gong, T., Wang, J., Yang, M., Shao, Y., Liu, J., Wu, Q., Xu, Q., Wang, H., He, X., Chen, Y., Xu, R., & Wang, Y.
- Affiliations
- Suzhou Municipal Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Suzhou Maternal and Child Healthcare Institute Maternal and Child Healthcare Department Suzhou Municipal Hospital Affiliated Hospital of Nanjing Medical University Suzhou China
- Corresponding author
- Gong, Tian
- Venue
- Journal of Diabetes Investigation
- Publisher
- Wiley
- Published
- 2016-01-20
- Volume
- 7
- Issue
- 4
- Pages
- 622-628
- ISSN
- 2040-1116 (ISSN-L)
- 2040-1124
- PMC
- PMC4931215
- OpenAlex
- W2215148278
- Cited by
- 62
- References
- 2
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 5 · 2023: 5 · 2022: 9 · 2021: 10 · 2020: 6 · 2019: 11 · 2018: 3 · 2017: 2 · 2016: 1
- FWCI
- 0.30
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Journal of Diabetes Investigation (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Nursing › Nutrition and Dietetics › Folate and B Vitamins Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- homocysteine, hyperhomocysteinemia, gestational diabetes mellitus, insulin resistance, second trimester, maternal age, serum biomarkers, pregnancy
- MeSH terms
- Adult, Female, Homocysteine, Humans, Pregnancy, Diabetes, Gestational
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