Cited by 31Dermatologic Treatments and ResearchBody Contouring and SurgeryFacial Rejuvenation and Surgery Techniques

The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.

An overview of the role of carboxytherapy in dermatology

Open access

Abstract

Background: Carboxytherapy is defined as intradermal and/or subcutaneous microinjections of sterile purified carbon dioxide into different parts of the body for therapeutic aims. The vasodilatation effect and intradermal collagen reorganization associated with carboxytherapy have advantages for aesthetic dermatology and cosmetology. Objective: In the current article, we have reviewed some of the most important indications of this modality in dermatology and aesthetic dermatology. Method: Our review is a narrative one which has gathered some of the most important indications of carboxytherapy in dermatology and cosmetology. Results: Carboxytherapy has successfully been applied for some dermatologic and cosmetic conditions among which skin aging, cellulite, localized fat deposits, striae distensae, infraorbital hyperpigmentation, scar, lymphedema, androgenetic alopecia, alopecia areata, psoriasis, morphea, and vitiligo are the most important. Conclusion: Carboxytherapy can be considered as a safe, minimally‐invasive modality used for rejuvenation, restoration, and recondition of the skin.

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Integrity signals

Registry

Crossref · 10.1111/jocd.15741

Cites

43 of 43 references verified0 citation errors · 0 not checkable

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  • There are potential risks associated with carboxytherapy such as topical CO2-releasing gels or subcutaneous applications used in wound management.

    “This implies potential risks associated with carboxytherapy such as topical CO2-releasing gels or subcutaneous applications52 used in wound management.”

    From Candida auris skin tropism and antifungal resistance are mediated by carbonic anhydrase Nce103 (2025) · cites this paper as [52]

    The ‘Complications of Carboxytherapy’ section reports pain, burning, bruising, hematomas, and persistent edema, supporting the general point that treatment has potential risks. The Introduction describes subcutaneous CO2 injections and earlier topical application, but the cited passages do not establish risks of CO2-releasing gels or of these applications specifically in wound management. Page numbers are unavailable in our copy. (LLM, conf=0.85)

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Citations

Cites

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Research works printed but not linked: 3

  1. Farouk S, 2021, Efficacy of carboxytherapy in treatment of stretch marks, Sci J Al‐Azhar Med Fac Girls, 5, 836
  2. El‐Fakahany H, 2016, Connective tissue diseases: treatment of localized morphea in face and body using carboxytherapy, case report, J Am Acad Dermatol, 74
  3. Cobb C, 2022, What you should know about carboxytherapy

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Metadata

Authors
Bagherani, N., Smoller, B. R., Tavoosidana, G., Ghanadan, A., Wollina, U., & Lotti, T.
Affiliations
  • Arak University of Medical Sciences (IR)
  • University of Rochester Medicine (US)
  • Tehran University of Medical Sciences (IR)
  • Imam Khomeini Hospital (IR)
  • Städtisches Klinikum Dresden (DE)
  • Marconi University (IT)
Corresponding author
  • Bagherani, Nooshin
  • Tavoosidana, Gholamreza
Venue
Journal of Cosmetic Dermatology
Publisher
Wiley
Published
2023-03-31
Volume
22
Issue
9
Pages
2399-2407
ISSN
  • 1473-2130 (ISSN-L)
  • 1473-2165
OpenAlex
W4362458019
Cited by
31
References
43
Citations by year
2026: 9 · 2025: 9 · 2024: 8 · 2023: 5
FWCI
1.43
Type
journal article
Language
en
Open access
Locations
  • Journal of Cosmetic Dermatology (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
  • Health Sciences › Medicine › Surgery › Body Contouring and Surgery
  • Health Sciences › Medicine › Dermatology › Facial Rejuvenation and Surgery Techniques
Keywords
carboxytherapy, cosmetic dermatology, skin aging, cellulite, localized fat deposits, striae, scar treatment, lymphedema, androgenetic alopecia, alopecia areata, psoriasis, morphea, vitiligo, collagen reorganization, vasodilation
MeSH terms
Alopecia Areata, Carbon Dioxide, Dermatology, Humans, Skin, Striae Distensae

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