The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
An overview of the role of carboxytherapy in dermatology
Open accessAbstract
Background: Carboxytherapy is defined as intradermal and/or subcutaneous microinjections of sterile purified carbon dioxide into different parts of the body for therapeutic aims. The vasodilatation effect and intradermal collagen reorganization associated with carboxytherapy have advantages for aesthetic dermatology and cosmetology. Objective: In the current article, we have reviewed some of the most important indications of this modality in dermatology and aesthetic dermatology. Method: Our review is a narrative one which has gathered some of the most important indications of carboxytherapy in dermatology and cosmetology. Results: Carboxytherapy has successfully been applied for some dermatologic and cosmetic conditions among which skin aging, cellulite, localized fat deposits, striae distensae, infraorbital hyperpigmentation, scar, lymphedema, androgenetic alopecia, alopecia areata, psoriasis, morphea, and vitiligo are the most important. Conclusion: Carboxytherapy can be considered as a safe, minimally‐invasive modality used for rejuvenation, restoration, and recondition of the skin.
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There are potential risks associated with carboxytherapy such as topical CO2-releasing gels or subcutaneous applications used in wound management.
“This implies potential risks associated with carboxytherapy such as topical CO2-releasing gels or subcutaneous applications52 used in wound management.”
From Candida auris skin tropism and antifungal resistance are mediated by carbonic anhydrase Nce103 (2025) · cites this paper as [52]
The ‘Complications of Carboxytherapy’ section reports pain, burning, bruising, hematomas, and persistent edema, supporting the general point that treatment has potential risks. The Introduction describes subcutaneous CO2 injections and earlier topical application, but the cited passages do not establish risks of CO2-releasing gels or of these applications specifically in wound management. Page numbers are unavailable in our copy. (LLM, conf=0.85)
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Metadata
- Authors
- Bagherani, N., Smoller, B. R., Tavoosidana, G., Ghanadan, A., Wollina, U., & Lotti, T.
- Affiliations
- Arak University of Medical Sciences (IR)
- University of Rochester Medicine (US)
- Tehran University of Medical Sciences (IR)
- Imam Khomeini Hospital (IR)
- Städtisches Klinikum Dresden (DE)
- Marconi University (IT)
- Corresponding author
- Bagherani, Nooshin
- Tavoosidana, Gholamreza
- ORCID
- Venue
- Journal of Cosmetic Dermatology
- Publisher
- Wiley
- Published
- 2023-03-31
- Volume
- 22
- Issue
- 9
- Pages
- 2399-2407
- ISSN
- 1473-2130 (ISSN-L)
- 1473-2165
- OpenAlex
- W4362458019
- Cited by
- 31
- References
- 43
- Citations by year
- 2026: 9 · 2025: 9 · 2024: 8 · 2023: 5
- FWCI
- 1.43
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Cosmetic Dermatology (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
- Health Sciences › Medicine › Surgery › Body Contouring and Surgery
- Health Sciences › Medicine › Dermatology › Facial Rejuvenation and Surgery Techniques
- Keywords
- carboxytherapy, cosmetic dermatology, skin aging, cellulite, localized fat deposits, striae, scar treatment, lymphedema, androgenetic alopecia, alopecia areata, psoriasis, morphea, vitiligo, collagen reorganization, vasodilation
- MeSH terms
- Alopecia Areata, Carbon Dioxide, Dermatology, Humans, Skin, Striae Distensae
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