Identification of predictive factors for the probability of pregnancy following ovulation stimulation‐intra‐uterine insemination cycles in terms of female and male
Abstract
Aim To identify which positive prognostic parameters contribute to successful treatment outcomes and the probability of pregnancy by analyzing the results of infertile couples underwent ovulation stimulation (OS) and intra-uterine insemination (IUI) in our clinic. Methods Five hundred and nineteen couples who underwent OS-IUI treatment because of a mild-moderate male factor, unexplained infertility, or anovulation were retrospectively analyzed. The data collected included patient demographics, cycle characteristic, sperm parameters and pregnancy rates. The main outcome measure was pregnancy rate (PR). Results Our overall PR was 17.72% (n = 92). In women who did not achieve pregnancy, age, BMI and duration of infertility were significantly higher (P 2 (OR = 0.87; 95% CI: 0.80-0.95; P = 0.002) and AFC > 9 (OR = 1.07; 95% CI: 1-1.15; P = 0.034) increase the pregnancy. Conclusion Younger women, especially those with unexplained infertility, primary infertility, shorter duration of infertility, normal ovarian reserve, higher motile spermatozoa inseminated and sperm morphology, could benefit from OS-IUI.
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Ozcan et al. found similar results after analysis of more than 500 IUI cycles.
“The findings of Ozcan et al. [85] were similar after analysis of more than 500 IUI cycles.”
From Recommendations for Human Sperm Morphology Assessment in 2025: An Expert Review From the French BLEFCO Group (2026) · cites this paper as [85]
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- Authors
- Ozcan, P., & Takmaz, T.
- Affiliations
- Department of Obstetrics and Gynecology, Faculty of Medicine Bezmialem Vakif University İstanbul Turkey
- Bezmiâlem Vakıf Üniversitesi (TR)
- Venue
- Journal of Obstetrics and Gynaecology Research
- Publisher
- Wiley
- Published
- 2021-01-05
- Volume
- 47
- Issue
- 3
- Pages
- 893-899
- ISSN
- 1341-8076 (ISSN-L)
- 1447-0756
- OpenAlex
- W3119125482
- Cited by
- 7
- References
- 18
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 1 · 2022: 1 · 2021: 1
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of obstetrics and gynaecology research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Keywords
- ovulation induction, intrauterine insemination, pregnancy rate, predictive factors, unexplained infertility, anovulation, male factor infertility, ovarian reserve, antral follicle count, sperm morphology, motile spermatozoa, infertility duration, primary infertility, maternal age
- MeSH terms
- Female, Humans, Infertility, Insemination, Male, Ovulation, Ovulation Induction, Pregnancy, Probability, Retrospective Studies, Pregnancy Rate
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