The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Antifungal Activity of Apple Cider Vinegar on Candida Species Involved in Denture Stomatitis
Abstract
Purpose: To evaluate the in vitro antifungal activity of apple cider vinegar on Candida spp. involved in denture stomatitis. Material and Methods: The microdilution technique was used to determine the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of apple cider vinegar containing 4% maleic acid, and nystatin (control). Further tests of microbial kinetics and inhibition of adherence to acrylic resin were performed testing different concentrations (MIC, MICx2, MICx4) of the products at time intervals of 0, 30, 60, 120 and 180 minutes. A roughness meter was used to measure the changes in surface roughness; color change of the acrylic resin specimens exposed to the test products in different concentrations and time intervals were also evaluated. Results: Apple cider vinegar (4%) showed MIC of 2500 μg/ml and MFC of 2500, 5000, and 10,000 μg/ml depending on the strain tested. Nystatin showed MIC of 3.125 μg/ml and strain‐dependent MFC values ranging from 3.125 to 12.5 μg/ml. The microbial kinetic assay showed a statistical difference between apple cider vinegar and nystatin (p < 0.0001). After 30 minutes of exposure, apple cider vinegar showed fungicidal effect at MICx4, whereas nystatin maintained its fungistatic effect. Apple cider vinegar showed greater inhibition of adherence (p < 0.001) compared to control. Apple cider vinegar did not significantly alter the surface roughness of the acrylic resin specimens compared to nystatin (p > 0.05), and both had no influence on their color. Conclusion: Apple cider vinegar showed antifungal properties against Candida spp., thus representing a possible therapeutic alternative for patients with denture stomatitis.
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In the citing paper
“On the other hand, antifungal activity of vinegar was established against Candida albicans spp. involved in dental stomatitis [104].”
From Fruits Vinegar: Quality Characteristics, Phytochemistry, and Functionality (2021) · cites this paper as [104]
Citations
Cites
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The effects of Pluronic block copolymers on the aggregation state of nystatin
Croy, S., & Kwon, G. S. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2003.11.003 · Cited by 126
Fungicidal activity of miconazole against Candida spp. biofilms
Vandenbosch, D., Braeckmans, K., Nelis, H. J., & Coenye, T. (2010) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkq019 · Cited by 113
Protective Effects of Organic Acids on Survival of Escherichia coli O157:H7 in Acidic Environments
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Surface roughness of composite resins after finishing and polishing
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- 10.1590/S0103-64402006000300004 · DOI
Cited by
Yagnik, D., Serafin, V., & J. Shah, A. (2018) · Scientific Reports · doi:10.1038/s41598-017-18618-x · Cited by 117
Fruits Vinegar: Quality Characteristics, Phytochemistry, and Functionality
Ousaaid, D., Mechchate, H., Laaroussi, H., Hano, C., Bakour, M., El Ghouizi, A., Conte, R., Lyoussi, B., & El Arabi, I. (2021) · Molecules · doi:10.3390/molecules27010222 · Cited by 81
Metadata
- Authors
- Mota, A. C. L. G., de Castro, R. D., de Araújo Oliveira, J., & de Oliveira Lima, E.
- Affiliations
- Postgraduate Program in Dentistry João Pessoa Paraíba Brazil
- Venue
- Journal of Prosthodontics
- Publisher
- Wiley
- Published
- 2014-09-14
- Volume
- 24
- Issue
- 4
- Pages
- 296-302
- ISSN
- 1059-941X (ISSN-L)
- 1532-849X
- OpenAlex
- W1589062204
- Cited by
- 34
- References
- 43
- Citations by year
- 2026: 3 · 2024: 1 · 2023: 3 · 2022: 2 · 2021: 8 · 2020: 1 · 2019: 5 · 2018: 5 · 2017: 3 · 2016: 2 · 2015: 1
- FWCI
- 1.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Prosthodontics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Keywords
- apple cider vinegar, antifungal activity, Candida, denture stomatitis, minimum inhibitory concentration, minimum fungicidal concentration, microbial kinetics, fungal adhesion, acrylic resin, surface roughness, nystatin, maleic acid
- MeSH terms
- Antifungal Agents, Candida albicans, Candidiasis, Humans, Microbial Sensitivity Tests, Stomatitis, Denture, Acetic Acid, Malus
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