The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.
Phytomelatonin receptor PMTR 1‐mediated signaling regulates stomatal closure in Arabidopsis thaliana
Abstract
Melatonin has been detected in plants in 1995; however, the function and signaling pathway of this putative phytohormone are largely undetermined due to a lack of knowledge about its receptor. Here, we discovered the first phytomelatonin receptor ( CAND 2/ PMTR 1) in Arabidopsis thaliana and found that melatonin governs the receptor‐dependent stomatal closure. The application of melatonin induced stomatal closure through the heterotrimeric G protein α subunit‐regulated H 2 O 2 and Ca 2+ signals. The Arabidopsis mutant lines lacking AtCand2 that encodes a candidate G protein‐coupled receptor were insensitive to melatonin‐induced stomatal closure. Accordingly, the melatonin‐induced H 2 O 2 production and Ca 2+ influx were completely abolished in cand2 . CAND 2 is a membrane protein that interacts with GPA 1 and the expression of AtCand2 was tightly regulated by melatonin in various organs and guard cells. CAND 2 showed saturable and specific 125 I‐melatonin binding, with apparent K d (dissociation constant) of 0.73 ± 0.10 nmol/L ( r 2 = .99), demonstrating this protein is a phytomelatonin receptor ( PMTR 1). Our results suggest that the phytomelatonin regulation of stomatal closure is dependent on its receptor CAND 2/ PMTR 1‐mediated H 2 O 2 and Ca 2+ signaling transduction cascade.
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Jahan, M. S., Guo, S., Baloch, A. R., Sun, J., Shu, S., Wang, Y., Ahammed, G. J., Kabir, K., & Roy, R. (2020) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.110593 · Cited by 365
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Back, K. (2021) · The Plant Journal · doi:10.1111/tpj.14915 · Cited by 281
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Metadata
- Authors
- Wei, J., Li, D., Zhang, J., Shan, C., Rengel, Z., Song, Z., & Chen, Q.
- Venue
- Journal of Pineal Research
- Publisher
- Wiley
- Published
- 2018-05-21
- Volume
- 65
- Issue
- 2
- Pages
- e12500-e12500
- ISSN
- 0742-3098 (ISSN-L)
- 1600-079X
- OpenAlex
- W2799888831
- Cited by
- 432
- References
- 57
- FWCI
- 25.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wei, J., Li, D., Zhang, J., Shan, C., Rengel, Z., Song, Z., & Chen, Q. (2018). Phytomelatonin receptor PMTR 1‐mediated signaling regulates stomatal closure in Arabidopsis thaliana. Journal of Pineal Research. https://doi.org/10.1111/jpi.12500
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