The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Burden of severe periodontitis and edentulism in 2021, with projections up to 2050: The Global Burden of Disease 2021 study
Open accessAbstract
Aim: To (i) assess the prevalence, incidence, and burden of severe periodontitis and edentulism in 2021, and (ii) forecast their rates in 2050. Methods: Prevalence, incidence, and Years Lived with Disability (YLDs) for severe periodontitis and edentulism in 2021 were gathered globally, covering 204 countries, seven super regions, and 21 regions from the Global Burden of Disease (GBD) 2021 study. Prevalence, incidence, and YLDs due to periodontitis and edentulism to 2050 were projected using mixed‐effects models with the socio‐demographic index as the main covariate. Results: In 2021, over 1 billion people were affected by severe periodontitis (1066.95 million; 95% UI: 896.55–1234.84), with a global age‐standardized prevalence of 12.50% (10.53–14.49). South Asia had the highest prevalence rate, at 17.57% (14.73; 20.14). Edentulism affected 353 million people globally (300.60–416.20), resulting in an age‐standardized prevalence of 4.11% (3.50; 4.83). The highest edentulism prevalence was found in Latin America and the Caribbean, at 7.39% (6.44; 8.39). By 2050, more than 1.5 billion people (+44.32%) are projected to have severe periodontitis, and over 660 million (+84.40%) to be edentulous. In the same year, 19.67% (130.23 million) of the edentulous people worldwide will be located in China. Severe periodontitis is expected to move up one position, and edentulism nine positions, among the most impactful Level 4 diseases/conditions affecting YLDs worldwide by 2050. Conclusion: Severe periodontitis and edentulism remain major public health challenges in 2021, with the number of affected individuals projected to rise significantly in the coming decades.
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Self-citationOng, K. L., Stafford, L. K., McLaughlin, S. A., Boyko, E. J., Vollset, S. E., Smith, A. E., Dalton, B. E., Duprey, J., Cruz, J. A., Hagins, H., et al. (2023) · The Lancet · doi:10.1016/s0140-6736(23)01301-6 · Cited by 4,681
Oral diseases: a global public health challenge
Peres, M. A., Macpherson, L. M. D., Weyant, R. J., Daly, B., Venturelli, R., Mathur, M. R., Listl, S., Celeste, R. K., Guarnizo-Herreño, C. C., Kearns, C., et al. (2019) · The Lancet · doi:10.1016/s0140-6736(19)31146-8 · Cited by 4,054
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Guidelines for accurate and transparent health estimates reporting: the GATHER statement
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Vollset, S. E., Ababneh, H. S., Abate, Y. H., Abbafati, C., Abbasgholizadeh, R., Abbasian, M., Abbastabar, H., Abd Al Magied, A. H. A., Abd ElHafeez, S., Abdelkader, A., et al. (2024) · The Lancet · doi:10.1016/s0140-6736(24)00685-8 · Cited by 1,025
Self-citationBhattacharjee, N. V., Schumacher, A. E., Aali, A., Abate, Y. H., Abbasgholizadeh, R., Abbasian, M., Abbasi-Kangevari, M., Abbastabar, H., Abd ElHafeez, S., Abd-Elsalam, S., et al. (2024) · The Lancet · doi:10.1016/s0140-6736(24)00550-6 · Cited by 629
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Cited by
Tay, J. R. H., Nascimento, G. G., & Romandini, M. (2026) · Journal of Periodontal Research · doi:10.1111/jre.70096 · Cited by 7
Self-citationImplementation Research Is Underdeveloped in Oral Health: Bridging the Gap
Tay, J. R. H., Bosworth, H. B., Fox, C. H., Gallagher, J. E., Jakubovics, N. S., Schwendicke, F., & Nascimento, G. G. (2026) · Journal of Dental Research · doi:10.1177/00220345251410462 · Cited by 7
“It has been estimated that more than 660 million people will be edentulous by 2050, with low-and low-middle-income countries being disproportionately affected (Nascimento et al 2024).”
Self-citationPardiñas López, S., Khouly, I., Aellos, F., Alccayhuaman, K. A., & Díaz Prado, S. M. (2026) · BMC Oral Health · doi:10.1186/s12903-026-08411-6
Metadata
- Authors
- Nascimento, G. G., Alves‐Costa, S., & Romandini, M.
- Venue
- Journal of Periodontal Research
- Publisher
- Wiley
- Published
- 2024-08-27
- Volume
- 59
- Issue
- 5
- Pages
- 823-867
- ISSN
- 0022-3484 (ISSN-L)
- 1600-0765
- OpenAlex
- W4401968324
- Cited by
- 396
- References
- 24
- FWCI
- 152.26
- Type
- journal article
- Language
- en
- Open access
- hybrid
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