Examining Postoperative Outcomes after Employing a Surgical Algorithm for Management of Peyronie's Disease: A Single-Institution Retrospective Review
Abstract
Aim Surgery remains the gold standard treatment for men with stable Peyronie's disease (PD). In an attempt to guide operative selection, we report our series of penile-straightening procedures for PD, using a surgical algorithm that recommended tunica albuginea plication (TAP), partial plaque excision and grafting (PEG) or inflatable penile prosthesis (IPP) placement. With this study, we attempt to further refine surgical approach, define realistic surgical outcomes, and help establish reasonable postoperative expectations for treatment of PD. Methods We retrospectively reviewed all patients who underwent surgery for PD at our institution between 2007 and 2013. Work-up involved a history, physical exam, and a duplex ultrasound. Several questionnaires were employed to assess bother and distress associated with PD. Objective outcomes and patient satisfaction were assessed postoperatively. Primary outcomes include postoperative patient satisfaction with rigidity, curvature, and ability to engage in intercourse. Secondary outcomes include comparing emotional, relationship, and psychological distress to severity of disease. Results A total of 390 patients underwent penile-straightening procedures for correction of PD. Of these patients, 29%, (n = 114) underwent TAP, 41% (n = 159) PEG, and 30% (N = 114) IPP. Mean follow-up was 17 months. The three surgical modalities showed no significant difference in satisfaction with penile rigidity, presence of bothersome residual curve, or abi…
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Levine and Lenting were among the first to describe a surgical algorithm for Peyronie's disease based on curvature severity, indentation or hourglass with hinge-effect, and baseline erectile function.
“Levine and Lenting were one of the first groups to describe their surgical algorithm for Peyronie’s Disease based on curvature severity, presence of indentation/hourglass with associated hinge-effect, and baseline erectile function.”
From Comparing and Contrasting Peyronie's Disease Guidelines: Points of Consensus and Deviation. (2021) · cites this paper as [40]
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The Chronology of Depression and Distress in Men with Peyronie's Disease
Nelson, C. J., Diblasio, C., Kendirci, M., Hellstrom, W., Guhring, P., & Mulhall, J. P. (2008) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2008.00895.x · Cited by 255 · see citing works
Hellstrom, W. J. G., Feldman, R., Rosen, R. C., Smith, T., Kaufman, G., & Tursi, J. (2013) · Journal of Urology · doi:10.1016/j.juro.2013.01.090 · Cited by 210 · see citing works
Levine, L., & Dimitriou, R. (2000) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3900515 · Cited by 113 · see citing works
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Peyronie’s disease: Contemporary evaluation and management
Ziegelmann, M. J., Bajic, P., & Levine, L. A. (2020) · International Journal of Urology · doi:10.1111/iju.14230 · Cited by 86 · see citing works
Self-citationNonsurgical management of Peyronie’s disease
Tsambarlis, P., & Levine, L. A. (2019) · Nature Reviews Urology · doi:10.1038/s41585-018-0117-7 · Cited by 64 · see citing works
Self-citationComparing and Contrasting Peyronie's Disease Guidelines: Points of Consensus and Deviation.
Manka, M. G., White, L. A., Yafi, F. A., Mulhall, J. P., Levine, L. A., & Ziegelmann, M. J. (2021) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2020.11.013 · Cited by 28 · see citing works
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- Authors
- Papagiannopoulos, D., Yura, E., & Levine, L.
- Affiliations
- Rush University Medical Center (US)
- Corresponding author
- Levine, Laurence
- Venue
- The Journal of Sexual Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2015-06-01
- Volume
- 12
- Issue
- 6
- Pages
- 1474-1480
- ISSN
- 1743-6095 (ISSN-L)
- 1743-6109
- OpenAlex
- W1910680421
- Cited by
- 36
- References
- 3
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 3 · 2020: 8 · 2019: 7 · 2018: 4 · 2017: 4 · 2016: 2 · 2015: 2
- FWCI
- 3.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- The Journal of Sexual Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Urology › Urological Disorders and Treatments
- Health Sciences › Medicine › Rheumatology › Dupuytren's Contracture and Treatments
- Keywords
- Peyronie's disease, surgical algorithm, tunica albuginea plication, inflatable penile prosthesis, penile curvature, penile rigidity, patient satisfaction, psychological distress, postoperative outcomes
- MeSH terms
- Adult, Algorithms, Humans, Male, Middle Aged, Penile Induration, Penis, Postoperative Period, Surveys and Questionnaires, Retrospective Studies, Penile Prosthesis, Patient Satisfaction, Ultrasonography, Doppler, Duplex
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