The versatile heparin in COVID-19

Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia

Tang, N., Li, D., Wang, X., & Sun, Z.-Y. (2020) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14768 · Cited by 5,527 · see citing works

Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy

Tang, N., Bai, H., Chen, X., Gong, J., Li, D., & Sun, Z. (2020) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14817 · Cited by 3,554 · see citing works

Extracellular histones are major mediators of death in sepsis

Xu, J., Zhang, X., Pelayo, R., Monestier, M., Ammollo, C. T., Semeraro, F., Taylor, F. B., Esmon, N. L., Lupu, F., & Esmon, C. T. (2009) · Nature Medicine · doi:10.1038/nm.2053 · Cited by 1,547 · see citing works

Coronaviruses and the cardiovascular system: acute and long-term implications

Xiong, T., Redwood, S. R., Prendergast, B., & Chen, M. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa231 · Cited by 829 · see citing works

Herpesviruses and heparan sulfate: an intimate relationship in aid of viral entry

Shukla, D., & Spear, P. G. (2001) · Journal of Clinical Investigation · doi:10.1172/jci13799 · Cited by 497 · see citing works

Herpesviruses and heparan sulfate: an intimate relationship in aid of viral entry

Shukla, D., & Spear, P. G. (2001) · Journal of Clinical Investigation · doi:10.1172/jci200113799 · Cited by 454 · see citing works

New criteria for sepsis-induced coagulopathy (SIC) following the revised sepsis definition: a retrospective analysis of a nationwide survey

Iba, T., Nisio, M. D., Levy, J. H., Kitamura, N., & Thachil, J. V. (2017) · BMJ Open · doi:10.1136/bmjopen-2017-017046 · Cited by 438 · see citing works

The anti-inflammatory effects of heparin and related compounds

Young, E. (2007) · Thrombosis Research · doi:10.1016/j.thromres.2006.10.026 · Cited by 390 · see citing works

Coagulation, fibrinolysis, and fibrin deposition in acute lung injury

Idell, S. (2003) · Critical Care Medicine · doi:10.1097/01.ccm.0000057846.21303.ab · Cited by 381 · see citing works

Anti-Inflammatory Effects of Heparin and Its Derivatives: A Systematic Review

Mousavi, S., Moradi, M., Khorshidahmad, T., & Motamedi, M. (2015) · Advances in Pharmacological Sciences · doi:10.1155/2015/507151 · Cited by 260 · see citing works

Blood coagulation in immunothrombosis—At the frontline of intravascular immunity

Gaertner, F. C., & Maßberg, S. (2016) · Seminars in Immunology · doi:10.1016/j.smim.2016.10.010 · Cited by 233 · see citing works

Heparin, heparan sulfate and heparanase in inflammatory reactions

Vlodavsky, I., & Li, J. (2009) · Thrombosis and Haemostasis · doi:10.1160/th09-02-0091 · Cited by 208 · see citing works

More than an anticoagulant: Do heparins have direct anti-inflammatory effects?

Poterucha, T. J., Libby, P., & Goldhaber, S. Z. (2016) · Thrombosis and Haemostasis · doi:10.1160/th16-08-0620 · Cited by 198 · see citing works

Targeting factor Xa and thrombin: impact on coagulation and beyond

Esmon, C. T. (2013) · Thrombosis and Haemostasis · doi:10.1160/th13-09-0730 · Cited by 147 · see citing works

Coronaviridaeand SARS-associated Coronavirus Strain HSR1

Vicenzi, E., Canducci, F., Pinna, D., Mancini, N., Carletti, S., Lazzarin, A., Bordignon, C., Poli, G., & Clementi, M. (2004) · Emerging infectious diseases · doi:10.3201/eid1003.030683 · Cited by 132 · see citing works

Bronchoalveolar hemostasis in lung injury and acute respiratory distress syndrome

Glas, G. J., van der Sluijs, K. F., Schultz, M. J., et al. (2012) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.12047 · Cited by 118 · see citing works

Unfractionated Heparin Alleviates Sepsis-Induced Acute Lung Injury by Protecting Tight Junctions

Liu, Y., Mu, S., Li, X., et al. (2019) · Journal of Surgical Research · doi:10.1016/j.jss.2019.01.020 · Cited by 106 · see citing works

Heparin prevents Zika virus induced-cytopathic effects in human neural progenitor cells

Ghezzi, S., Cooper, L. C., Rubio, A., et al. (2017) · Antiviral Research · doi:10.1016/j.antiviral.2016.12.023 · Cited by 96 · see citing works

Heparins attenuated histone-mediated cytotoxicity in vitro and improved the survival in a rat model of histone-induced organ dysfunction

Iba, T., Hashiguchi, N., Nagaoka, I., Tabe, Y., Kadota, K., & Sato, K. (2015) · Intensive Care Medicine Experimental · doi:10.1186/s40635-015-0072-z · Cited by 87 · see citing works

Activation of Coagulation and Fibrinolysis in Acute Respiratory Distress Syndrome: A Prospective Pilot Study

Ozoliņa, A., Šarkele, M., Sabeļņikovs, O., Šķesters, A., Jaunalksne, I., Serova, J., Ievins, T., Bjertnæs, L. J., & Vanags, I. (2016) · Frontiers in Medicine · doi:10.3389/fmed.2016.00064 · Cited by 77 · see citing works

Unfractionated heparin attenuates histone-mediated cytotoxicity in vitro and prevents intestinal microcirculatory dysfunction in histone-infused rats

Zhu, C., Liang, Y., Li, X., et al. (2019) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0000000000002387 · Cited by 43 · see citing works

Effects of nebulized antithrombin and heparin on inflammatory and coagulation alterations in an acute lung injury model in rats

Camprubí–Rimblas, M., Tantinyà, N., Guillamat‐Prats, R., et al. (2019) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14685 · Cited by 42 · see citing works

Failure of chemical thromboprophylaxis in critically ill medical and surgical patients with sepsis

Hanify, J., Dupree, L. H., Johnson, D. W., et al. (2016) · Journal of Critical Care · doi:10.1016/j.jcrc.2016.10.002 · Cited by 38 · see citing works

Evaluation of the effects of low molecular weight heparin on inflammation and collagen deposition in chronic coxsackievirus B3-induced myocarditis in A/J mice.

Frizelle, S. P., Schwarz, J. E., Huber, S. A., & Leslie, K. (1992) · PubMed Central · Cited by 35 · see citing works

Protective effects of heparin on endothelial cells in sepsis.

Ma, J., & Bai, J. (2015) · PubMed · Cited by 23 · see citing works

Adjunctive therapy with low-molecular-weight heparin in patients with chronic heart failure secondary to dilated cardiomyopathy: One-year follow-up results of the randomized trial

Wojnicz, R., Nowak, J. U., Szyguła‐Jurkiewicz, B., Wilczek, K. L., Lekston, A., Trzeciak, P., Nowalany-Kozielska, E., Zembala, M., Wodniecki, J., & Poloński, L. (2006) · American Heart Journal · doi:10.1016/j.ahj.2006.06.028 · Cited by 21 · see citing works

Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy

Lodigiani, C., Iapichino, G., Carenzo, L., Cecconi, M., Ferrazzi, P., Sebastian, T., Kucher, N., Studt, J.-D., Sacco, C., Bertuzzi, A., et al. (2020) · Thrombosis Research · doi:10.1016/j.thromres.2020.04.024 · Cited by 2,054 · see citing works

COVID-19: Hemoglobin, Iron, and Hypoxia beyond Inflammation. A Narrative Review

Cavezzi, A., Troiani, E., & Corrao, S. (2020) · Clinics and Practice · doi:10.4081/cp.2020.1271 · Cited by 430 · see citing works

Thrombotic complications of COVID-19

Avila, J., Long, B., Holladay, D., & Gottlieb, M. (2021) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2020.09.065 · Cited by 143 · see citing works

Role of pirfenidone in TGF-β pathways and other inflammatory pathways in acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: a theoretical perspective

Hamidi, S. H., Kadamboor Veethil, S., & Hamidi, S. H. (2021) · Pharmacological Reports · doi:10.1007/s43440-021-00255-x · Cited by 50 · see citing works

Acute mesenteric ischemia in COVID-19 patients

Serban, D., Tribus, L. C., Vancea, G., Stoian, A. P., Dascalu, A. M., Suceveanu, A. I., Tanasescu, C., Costea, A. C., Tudosie, M. S., Tudor, C., et al. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm11010200 · Cited by 46 · see citing works

Superior Mesenteric Artery Thrombosis in COVID-19 Pneumonia: An Underestimated Diagnosis—First Case Report in Asia

Karna, S. T., Panda, R., Maurya, A. P., & Kumari, S. (2020) · Indian Journal of Surgery · doi:10.1007/s12262-020-02638-5 · Cited by 32 · see citing works

EARLY POST-TRAUMATIC COAGULOPATHY IN MULTIPLY INJURY

Maegele, M., Yuecel, N., Lefering, R. L., et al. (2006) · Shock · doi:10.1097/00024382-200606001-00170 · Cited by 2 · see citing works

Coagulopathy in patients who experience snakebite

Kim, J. S., Yang, J. W., Kim, M. S., et al. (2008) · The Korean Journal of Internal Medicine · doi:10.3904/kjim.2008.23.2.94 · Cited by 34 · see citing works

Acute Traumatic Coagulopathy

Brohi, K., Singh, J., Heron, M., & Coats, T. (2003) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/01.ta.0000069184.82147.06 · Cited by 1,728 · see citing works

Is delayed coagulopathy still difficult to anticipate after snakebite? An illustrative case report

Adebayo, B. O. (2013) · Journal of Clinical Medicine and Research · doi:10.5897/jcmr2013.0236 · Cited by 1 · see citing works

Coagulopathy in traumatic brain injury

Alexiou, G. Α., Pahatouridis, D., & Voulgaris, S. (2010) · Injury · doi:10.1016/j.injury.2010.06.019 · Cited by 170 · see citing works