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Genome‐based estimates of fungal rDNA copy number variation across phylogenetic scales and ecological lifestyles

Lofgren, Lotus A., Uehling, Jessie K., Branco, Sara, Bruns, Thomas D., Martin, Francis, Kennedy, Peter G.·2019·Molecular Ecology

Abstract

Ribosomal DNA (rDNA) copy number variation (CNV) has major physiological implications for all organisms, but how it varies for fungi, an ecologically ubiquitous and important group of microorganisms, has yet to be systemically investigated. Here, we examine rDNA CNV using an in silico read depth approach for 91 fungal taxa with sequenced genomes and assess copy number conservation across phylogenetic scales and ecological lifestyles. rDNA copy number varied considerably across fungi, ranging from an estimated 14 to 1,442 copies (mean = 113, median = 82), and copy number similarity was inversely correlated with phylogenetic distance. No correlations were found between rDNA CNV and fungal trophic mode, ecological guild or genome size. Taken together, these results show that like other microorganisms, fungi exhibit substantial variation in rDNA copy number, which is linked to their phylogeny in a scale‐dependent manner.

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Metadata

Authors
Lofgren, L. A., Uehling, J. K., Branco, S., Bruns, T. D., Martin, F., & Kennedy, P. G.
Venue
Molecular Ecology
Publisher
Wiley
Published
2019-02
Volume
28
Issue
4
Pages
721-730
ISSN
  • 0962-1083 (ISSN-L)
  • 1365-294X
OpenAlex
W2906359281
Cited by
267
References
43
FWCI
6.91
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Genome‐based estimates of fungal rDNA copy number variation across phylogenetic scales and ecological lifestyles. https://app.cochat.ai/papers/10.1111/mec.14995
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Lofgren, L. A., Uehling, J. K., Branco, S., Bruns, T. D., Martin, F., & Kennedy, P. G. (2019). Genome‐based estimates of fungal rDNA copy number variation across phylogenetic scales and ecological lifestyles. Molecular Ecology. https://doi.org/10.1111/mec.14995

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