The DOI matches its Crossref record; 144 of the 145 references it cites were found in a registry or an index.
A systematic review and meta‐analysis on the effects of exercise training versus hypocaloric diet: distinct effects on body weight and visceral adipose tissue
Open accessAbstract
Summary: Exercise training (‘exercise’) and hypocaloric diet (‘diet’) are frequently prescribed for weight loss in obesity. Whilst body weight changes are commonly used to evaluate lifestyle interventions, visceral adiposity (VAT) is a more relevant and stronger predictor for morbidity and mortality. A meta‐analysis was performed to assess the effects of exercise or diet on VAT (quantified by radiographic imaging). Relevant databases were searched through May 2014. One hundred seventeen studies (n = 4,815) were included. We found that both exercise and diet cause VAT loss (P < 0.0001). When comparing diet versus training, diet caused a larger weight loss (P = 0.04). In contrast, a trend was observed towards a larger VAT decrease in exercise (P = 0.08). Changes in weight and VAT showed a strong correlation after diet (R2 = 0.737, P < 0.001), and a modest correlation after exercise (R2 = 0.451, P < 0.001). In the absence of weight loss, exercise is related to 6.1% decrease in VAT, whilst diet showed virtually no change (1.1%). In conclusion, both exercise and diet reduce VAT. Despite a larger effect of diet on total body weight loss, exercise tends to have superior effects in reducing VAT. Finally, total body weight loss does not necessarily reflect changes in VAT and may represent a poor marker when evaluating benefits of lifestyle‐interventions.
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“During moderate weight loss, for example, 5% of initial body weight, the associated loss in visceral adipose tissue has been estimated at 21% in response to exercise and 13% in response to diet.”
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Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & the PRISMA Group* (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00135 · Cited by 37,554
Compendium of physical activities: an update of activity codes and MET intensities
AINSWORTH, B. E., HASKELL, W. L., WHITT, M. C., IRWIN, M. L., SWARTZ, A. M., STRATH, S. J., O???BRIEN, W. L., BASSETT, D. R., SCHMITZ, K. H., EMPLAINCOURT, P. O., et al. (2000) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200009001-00009 · Cited by 8,497
Mechanisms linking obesity to insulin resistance and type 2 diabetes
Kahn, S. E., Hull, R. L., & Utzschneider, K. M. (2006) · Nature · doi:10.1038/nature05482 · Cited by 5,448
HASKELL, W. L., LEE, I.-M., PATE, R. R., POWELL, K. E., BLAIR, S. N., FRANKLIN, B. A., MACERA, C. A., HEATH, G. W., THOMPSON, P. D., & BAUMAN, A. (2007) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3180616b27 · Cited by 4,616
Haslam, D. W., & James, W. P. T. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67483-1 · Cited by 3,757
Jensen, M. D., Ryan, D. H., Apovian, C. M., Ard, J. D., Comuzzie, A. G., Donato, K. A., Hu, F. B., Hubbard, V. S., Jakicic, J. M., Kushner, R. F., et al. (2014) · Circulation · doi:10.1161/01.cir.0000437739.71477.ee · Cited by 2,735
DONNELLY, J. E., BLAIR, S. N., JAKICIC, J. M., MANORE, M. M., RANKIN, J. W., & SMITH, B. K. (2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181949333 · Cited by 2,658
Pathophysiology of human visceral obesity: an update
Tchernof, A., & Després, J.-P. (2013) · Physiological Reviews · doi:10.1152/physrev.00033.2011 · Cited by 2,583
Boulé, N. G., Haddad, E., Kenny, G. P., Wells, G. A., & Sigal, R. J. (2001) · JAMA · doi:10.1001/jama.286.10.1218 · Cited by 1,889
Wildman, R. P. (2008) · Archives of Internal Medicine · doi:10.1001/archinte.168.15.1617 · Cited by 1,618
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1 of the 145 references couldn’t be matched to a known paper.
Research works printed but not linked: 7
- Law MSD, 1998, Critical Review Form, Quantitative Studies
- Irving B, 2006, Effects of exercise training intensity on abdominal fat in abdominally obese individuals with the metabolic syndrome, Diabetes, 55, A238
- Ku Y, 2009, Effect of resistance exercise on muscular subfascial adipose tissue and retinol‐binding protein‐4 concentration in individuals with diabetes, Diabetologia, 52, S270
- Haufe S, 2011, The influence of a low fat versus Low carbohydrate hypocaloric diet on intrahepatic fat content in overweight and obese human subjects, Obes Rev, 12, 216
- 10.1210/jc.78.6.1515 · DOI
- 10.1210/jc.84.8.2854 · DOI
- Koo BK, 2008, Changes of abdominal, thigh adipose tissue and skeletal muscle attenuation in response to energy restriction or exercise in overweight type 2 diabetes, Obesity, 16, S228
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Sorted by citations
Obesity and cardiovascular disease: a scientific statement from the American Heart Association
Powell-Wiley, T. M., Poirier, P., Burke, L. E., Després, J.-P., Gordon-Larsen, P., Lavie, C. J., Lear, S. A., Ndumele, C. E., Neeland, I. J., Sanders, P., et al. (2021) · Circulation · doi:10.1161/cir.0000000000000973 · Cited by 3,691
Ross, R., Neeland, I. J., Yamashita, S., Shai, I., Seidell, J., Magni, P., Santos, R. D., Arsenault, B., Cuevas, A., Hu, F. B., et al. (2020) · Nature Reviews Endocrinology · doi:10.1038/s41574-019-0310-7 · Cited by 1,966
Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement
Neeland, I. J., Ross, R., Després, J.-P., Matsuzawa, Y., Yamashita, S., Shai, I., Seidell, J., Magni, P., Santos, R. D., Arsenault, B., et al. (2019) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(19)30084-1 · Cited by 1,603
Neeland, I. J., Poirier, P., & Després, J.-P. (2018) · Circulation · doi:10.1161/circulationaha.117.029617 · Cited by 881
Wewege, M., van den Berg, R., Ward, R. E., & Keech, A. (2017) · Obesity Reviews · doi:10.1111/obr.12532 · Cited by 661
Metadata
- Authors
- Verheggen, R. J. H. M., Maessen, M. F. H., Green, D. J., Hermus, A. R. M. M., Hopman, M. T. E., & Thijssen, D. H. T.
- Affiliations
- Radboud University Nijmegen (NL)
- The University of Western Australia (AU)
- Department of Physiology Radboud University Medical Centre Nijmegen The Netherlands
- Corresponding author
- Verheggen, R. J. H. M.
- Venue
- Obesity Reviews
- Publisher
- Wiley
- Published
- 2016-05-23
- Volume
- 17
- Issue
- 8
- Pages
- 664-690
- ISSN
- 1467-7881 (ISSN-L)
- 1467-789X
- OpenAlex
- W2397931148
- Semantic Scholar
- 512581ef66a90e4e2c48fe3cbcf7ad8cf5add095
- Cited by
- 318
- References
- 145
- Citations by year
- 2026: 24 · 2025: 31 · 2024: 15 · 2023: 39 · 2022: 46 · 2021: 43 · 2020: 45 · 2019: 34 · 2018: 19 · 2017: 17 · 2016: 5
- FWCI
- 3.70
- Type
- journal article
- Language
- en
- Open access
- Locations
- Obesity Reviews (publishedVersion)
- PubMed (publishedVersion)
- Liverpool John Moores University (acceptedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- exercise training, hypocaloric diet, visceral adipose tissue, weight loss, obesity, weight loss interventions, lifestyle intervention, visceral fat
- MeSH terms
- Body Weight, Diet, Reducing, Humans, Obesity, Exercise, Randomized Controlled Trials as Topic, Caloric Restriction, Adiposity, Overweight
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