The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
OsNRAMP1 transporter contributes to cadmium and manganese uptake in rice
Abstract
Rice is a major dietary source of the toxic metal, cadmium (Cd). Previous studies reported that the rice transporter, OsNRAMP1, (Natural resistance‐associated macrophage protein 1) could transport iron (Fe), Cd and arsenic (As) in heterologous yeast assays. However, the in planta function of OsNRAMP1 remains unknown. Here, we showed that OsNRAMP1 was able to transport Cd and manganese (Mn) when expressed in yeast, but did not transport Fe or As. OsNRAMP1 was mainly expressed in roots and leaves and encoded a plasma membrane‐localized protein. OsNRAMP1 expression was induced by Cd treatment and Fe deficiency. Immunostaining showed that OsNRAMP1 was localized in all root cells, except the central vasculature, and in leaf mesophyll cells. The knockout of OsNRAMP1 resulted in significant decreases in root uptake of Cd and Mn and their accumulation in rice shoots and grains, and increased sensitivity to Mn deficiency. The knockout of OsNRAMP1 had smaller effects on Cd and Mn uptake than knockout of OsNRAMP5, while knockout of both genes resulted in large decreases in the uptake of the two metals. Taken together, OsNRAMP1 contributes significantly to the uptake of Mn and Cd in rice, and the functions of OsNRAMP1 and OsNRAMP5 are similar but not redundant.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
IRT1, an Arabidopsis Transporter Essential for Iron Uptake from the Soil and for Plant Growth
Vert, G., Grotz, N., Dédaldéchamp, F., Gaymard, F., Guerinot, M. L., Briat, J.-F., & Curie, C. (2002) · The Plant Cell · doi:10.1105/tpc.001388 · Cited by 1,679
Zhao, F., Hamon, R. E., Lombi, E., McLaughlin, M. J., & McGrath, S. P. (2002) · Journal of Experimental Botany · doi:10.1093/jexbot/53.368.535 · Cited by 385
Self-citation
Cited by
Sharma, J. K., Kumar, N., Singh, N. P., & Santal, A. R. (2023) · Frontiers in Plant Science · doi:10.3389/fpls.2023.1076876 · Cited by 423
Li, Z., Liang, Y., Hu, H., Shaheen, S. M., Zhong, H., Tack, F. M. G., Wu, M., Li, Y.-F., Gao, Y., Rinklebe, J., et al. (2021) · Environment International · doi:10.1016/j.envint.2021.106749 · Cited by 292
Jogawat, A., Yadav, B., Chhaya, & Narayan, O. P. (2021) · Physiologia Plantarum · doi:10.1111/ppl.13370 · Cited by 140
Advances in “Omics” Approaches for improving toxic metals/metalloids tolerance in plants
Raza, A., Tabassum, J., Zahid, Z., Charagh, S., Bashir, S., Barmukh, R., Khan, R. S. A., Barbosa, F., Zhang, C., Chen, H., et al. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2021.794373 · Cited by 132
State-of-the-Art OMICS Strategies against Toxic Effects of Heavy Metals in Plants: A Review
Rahman, S. U., Nawaz, M. F., Gul, S., Yasin, G., Hussain, B., Li, Y., & Cheng, H. (2022) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2022.113952 · Cited by 106
Metadata
- Authors
- Chang, J., Huang, S., Yamaji, N., Zhang, W., Ma, J. F., & Zhao, F.
- Venue
- Plant, Cell & Environment
- Publisher
- Wiley
- Published
- 2020-08-12
- Volume
- 43
- Issue
- 10
- Pages
- 2476-2491
- ISSN
- 0140-7791 (ISSN-L)
- 1365-3040
- OpenAlex
- W3042752572
- Cited by
- 415
- References
- 2
- FWCI
- 25.12
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: OsNRAMP1 transporter contributes to cadmium and manganese uptake in rice. https://app.cochat.ai/papers/10.1111/pce.13843
- The paper
- Chang, J., Huang, S., Yamaji, N., Zhang, W., Ma, J. F., & Zhao, F. (2020). OsNRAMP1 transporter contributes to cadmium and manganese uptake in rice. Plant, Cell & Environment. https://doi.org/10.1111/pce.13843
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
