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Cited by 96melanin and skin pigmentationDermatologic Treatments and ResearchGenetic and rare skin diseases.

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Quality of Life Impairment in Children and Adolescents with Vitiligo

Silverberg, Jonathan I., Silverberg, Nanette B.·2014·Pediatric Dermatology
DOI 10.1111/pde.12226
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Abstract

Vitiligo significantly affects quality of life (QOL) in adults, but little is known about the effect on QOL of pediatric vitiligo and whether the extent, distribution, and duration of vitiligo are associated with QOL. We performed an online parental questionnaire‐based study (N = 350) regarding children ages 0 to 17 years with vitiligo, including validated questions about body surface area (BSA), distribution, and age of onset of vitiligo, associated symptoms, and QOL using the Children's Dermatology Life Quality Index (CDLQI). Vitiligo negatively affected numerous aspects of and total CDLQI score (median 3.0, interquartile range 5.0). Their vitiligo lesions did not bother only 4.1% of teenagers ages 15 to 17 years, versus 45.6% of children ages 0 to 6 years and 50.0% of those ages 7 to 14 years (p < 0.001). There was no association between the child's age and whether the child's vitiligo bothered the parents (p = 0.27). The most bothersome sites of vitiligo lesions for children and parents were the face (25.6% and 37.4%, respectively) and legs (26.2% and 26.2%, respectively). Eighty‐two patients (30.1%) reported itching and painful skin within the past week. Using multivariate ordinal logistic regression models, it was found that an affected BSA of more than 25% was associated with self‐consciousness, difficulty with friendships and schoolwork, and teasing and bullying. Lesions on the face and arms were associated with teasing and bullying. The extent of vitiligo is associated with QOL impairment in children and adolescents, especially self‐consciousness, but also bullying and teasing. Different distributions of vitiligo lesions are associated with different aspects of QOL impairment. Teenagers ages 15 to 17 years seem to experience the most self‐consciousness of all pediatric age groups.

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Crossref · 10.1111/pde.12226

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Metadata

Authors
Silverberg, J. I., & Silverberg, N. B.
Affiliations
St. Luke's-Roosevelt Hospital Center (US)
Corresponding author
Silverberg, Jonathan I.
ORCID
Venue
Pediatric Dermatology
Publisher
Wiley
Published
2013-10-18
Volume
31
Issue
3
Pages
309-318
ISSN
  • 0736-8046 (ISSN-L)
  • 1525-1470
DOI
10.1111/pde.12226
OpenAlex
W2137650680
Cited by
96
References
18
Citations by year
2026: 4 · 2025: 10 · 2024: 11 · 2023: 13 · 2022: 8 · 2021: 4 · 2020: 7 · 2019: 7 · 2018: 8 · 2017: 6 · 2016: 5 · 2015: 7 · 2014: 5
FWCI
3.29
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Pediatric Dermatology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
  • Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
  • Health Sciences › Medicine › Dermatology › Genetic and rare skin diseases.
Keywords
pediatric vitiligo, quality of life, Children's Dermatology Life Quality Index, body surface area involvement, lesion distribution, age of onset, self-consciousness, bullying, teasing, pruritus, children and adolescents
MeSH terms
Adolescent, Child, Psychology, Child, Child, Preschool, Female, Health Surveys, Humans, Infant, Infant, Newborn, Life Style, Male, Parents, Quality of Life, Surveys and Questionnaires, Severity of Illness Index, Vitiligo, Logistic Models, Age of Onset

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