Humoral Pattern Recognition and the Complement System

Innate immune recognition

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Tolerance, Danger, and the Extended Family

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Approaching the asymptote? Evolution and revolution in immunology.Preprint

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The C‐type lectin superfamily in the immune system

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Structure of a C-type mannose-binding protein complexed with an oligosaccharide

Weis, W. I., Drickamer, K., & Hendrickson, W. A. (1992) · Nature · doi:10.1038/360127a0 · Cited by 886 · see citing works

Evolution of the lectin–complement pathway and its role in innate immunity

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C-type lectin-like domains

Drickamer, K. (1999) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(99)00009-3 · Cited by 624 · see citing works

The Chemistry and Structure of Collagen

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Inherent specificities in natural antibodies: a key to immune defense against pathogen invasion

Baumgarth, N., Tung, J. W., & Herzenberg, L. A. (2005) · Springer Seminars in Immunopathology · doi:10.1007/s00281-004-0182-2 · Cited by 545 · see citing works

The Classical Complement Pathway: Activation and Regulation of the First Complement Component

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C1q: Structure, function, and receptors

Kishore, U., & Reid, K. B. M. (2000) · Immunopharmacology · doi:10.1016/s0162-3109(00)80301-x · Cited by 480 · see citing works

Engineering galactose-binding activity into a C-type mannose-binding protein

Drickamer, K. (1992) · Nature · doi:10.1038/360183a0 · Cited by 477 · see citing works

C1q and tumor necrosis factor superfamily: modularity and versatility

Kishore, U., Gaboriaud, C., Waters, P. J., Shrive, A. K., Greenhough, T. J., Reid, K. B. M., Sim, R. B., & Arlaud, G. J. (2004) · Trends in Immunology · doi:10.1016/j.it.2004.08.006 · Cited by 437 · see citing works

The internal thioester and the covalent binding properties of the complement proteins C3 and C4

Law, S. K. A., & Dodds, A. W. (1997) · Protein Science · doi:10.1002/pro.5560060201 · Cited by 374 · see citing works

The Crystal Structure of the Globular Head of Complement Protein C1q Provides a Basis for Its Versatile Recognition Properties

Gaboriaud, C., Juanhuix, J., Gruez, A., Lacroix, M., Darnault, C., Pignol, D., Verger, D., Fontecilla-Camps, J. C., & Arlaud, G. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307764200 · Cited by 362 · see citing works

Detection of structural gene mutations and promoter polymorphisms in the mannan-binding lectin (MBL) gene by polymerase chain reaction with sequence-specific primers

Steffensen, R., Thiel, S., Varming, K., et al. (2000) · Journal of Immunological Methods · doi:10.1016/s0022-1759(00)00198-8 · Cited by 339 · see citing works

Cutting Edge: Complement-Activating Complex of Ficolin and Mannose-Binding Lectin-Associated Serine Protease

Matsushita, M., Endo, Y., & Fujita, T. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.5.2281 · Cited by 333 · see citing works

A Novel Human Serum Lectin with Collagen- and Fibrinogen-like Domains That Functions as an Opsonin

Matsushita, M., Endo, Y., Taira, S., et al. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.5.2448 · Cited by 330 · see citing works

The quantitative role of alternative pathway amplification in classical pathway induced terminal complement activation

HARBOE, M., ULVUND, G., VIEN, L., FUNG, M., & MOLLNES, T. E. (2004) · Clinical and Experimental Immunology · doi:10.1111/j.1365-2249.2004.02627.x · Cited by 319 · see citing works

Sequence dependent conformational variations of collagen triple-helical structure.

Berman, H. M., Kramer, R. Z., Bella, J., Mayville, P., & Brodsky, B. (1999) · Nature Structural Biology · doi:10.1038/8259 · Cited by 317 · see citing works

Beyond pattern recognition: five immune checkpoints for scaling the microbial threat

Blander, J. M., & Sander, L. E. (2012) · Nature reviews. Immunology · doi:10.1038/nri3167 · Cited by 286 · see citing works

Macromolecular organization of natural and recombinant lung surfactant protein SP 28–36

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Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2

Héja, D., Kocsis, A., Dobó, J., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1202588109 · Cited by 251 · see citing works

Human mannose-binding protein carbohydrate recognition domain trimerizes through a triple α-helical coiled-coil

Sheriff, S., Chang, C. Y., & Ezekowitz, R. A. B. (1994) · Nature Structural Biology · doi:10.1038/nsb1194-789 · Cited by 246 · see citing works

Human M-Ficolin Is a Secretory Protein That Activates the Lectin Complement Pathway

Liu, Y., Endo, Y., Iwaki, D., Nakata, M., Matsushita, M., Wada, I., Inoue, K., Munakata, M., & Fujita, T. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.5.3150 · Cited by 245 · see citing works

Molecular structure of pulmonary surfactant protein D (SP-D).

Crouch, E. C., Persson, A., Chang, D. S., et al. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32556-5 · Cited by 235 · see citing works

The reaction mechanism of the internal thioester in the human complement component C4

Dodds, A. W., Ren, X. D., Willis, A. C., & Law, S. K. A. (1996) · Nature · doi:10.1038/379177a0 · Cited by 224 · see citing works

The Membrane-type Collectin CL-P1 Is a Scavenger Receptor on Vascular Endothelial Cells

Ohtani, K., Suzuki, Y., Eda, S., Kawai, T., Kase, T., Keshi, H., Sakai, Y., Fukuoh, A., Sakamoto, T., Itabe, H., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103942200 · Cited by 217 · see citing works

Cloning and Characterization of the Hakata Antigen, a Member of the Ficolin/Opsonin p35 Lectin Family

Sugimoto, R., Yae, Y., Akaiwa, M., et al. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.33.20721 · Cited by 210 · see citing works

The human IgM pentamer is a mushroom-shaped molecule with a flexural bias

Czajkowsky, D. M., & Shao, Z. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903805106 · Cited by 207 · see citing works

L-ficolin Is a Pattern Recognition Molecule Specific for Acetyl Groups

Krarup, A., Thiel, S., Hansen, A. G., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407161200 · Cited by 205 · see citing works

Collectin 11 (CL-11, CL-K1) Is a MASP-1/3–Associated Plasma Collectin with Microbial-Binding Activity

Hansen, S., Selman, L., Palaniyar, N., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1002185 · Cited by 204 · see citing works

Structural insights into the innate immune recognition specificities of L‐ and H‐ficolins

Garlatti, V., Belloy, N., Martin, L., Lacroix, M., Matsushita, M., Endo, Y., Fujita, T., Fontecilla-Camps, J. C., Arlaud, G. J., Thielens, N. M., et al. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601500 · Cited by 197 · see citing works

Activation of the Lectin Complement Pathway by H-Ficolin (Hakata Antigen)

Matsushita, M., Kuraya, M., Hamasaki, N., Tsujimura, M., Shiraki, H., & Fujita, T. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.7.3502 · Cited by 193 · see citing works

Effect of Capsulation of Opportunistic Pathogenic Bacteria on Binding of the Pattern Recognition Molecules Mannan-Binding Lectin, L-Ficolin, and H-Ficolin

Krarup, A., Sørensen, U. B. S., Matsushita, M., et al. (2005) · Infection and Immunity · doi:10.1128/iai.73.2.1052-1060.2005 · Cited by 189 · see citing works

MAp44, a Human Protein Associated with Pattern Recognition Molecules of the Complement System and Regulating the Lectin Pathway of Complement Activation

Degn, S. E., Hansen, A. G., Steffensen, R., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0902388 · Cited by 185 · see citing works

Distinct physicochemical characteristics of human mannose binding protein expressed by individuals of differing genotype.

LIPSCOMBE, R. J., Sumiya, M., Summerfield, J. A., et al. (1995) · PubMed · Cited by 178 · see citing works

Essential role of Mannose-binding lectin-associated serine protease-1 in activation of the complement factor D

Takahashi, M., Ishida, Y., Iwaki, D., Kanno, K., Suzuki, T., Endo, Y., Homma, Y., & Fujita, T. (2009) · The Journal of Experimental Medicine · doi:10.1084/jem.20090633 · Cited by 173 · see citing works

Molecular cloning and characterization of ficolin, a multimeric protein with fibrinogen- and collagen-like domains

Ichijo, H., Hellman, U., Wernstedt, C., et al. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)85267-5 · Cited by 159 · see citing works

Circular-dichroism and electron-microscopy studies of human subcomponent C1q before and after limited proteolysis by pepsin

Brodsky-Doyle, B., Leonard, K., & Reid, K. B. M. (1976) · Biochemical Journal · doi:10.1042/bj1590279 · Cited by 159 · see citing works

M‐ficolin is expressed on monocytes and is a lectin binding to N‐acetyl‐ d ‐glucosamine and mediates monocyte adhesion and phagocytosis of Escherichia coli

Teh, C., Le, Y., Lee, S. H., & Lu, J. (2000) · Immunology · doi:10.1046/j.1365-2567.2000.00099.x · Cited by 156 · see citing works

Molecular Cloning of a Novel Human Collectin from Liver (CL-L1)

Ohtani, K., Suzuki, Y., Eda, S., Kawai, T., Kase, T., Yamazaki, H., Shimada, T., Keshi, H., Sakai, Y., Fukuoh, A., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.19.13681 · Cited by 154 · see citing works

Identification and Characterization of a Novel Human Collectin CL-K1

Keshi, H., Sakamoto, T., Kawai, T., Ohtani, K., Katoh, T., Jang, S., Motomura, W., Yoshizaki, T., Fukuda, M., Koyama, S., et al. (2006) · Microbiology and Immunology · doi:10.1111/j.1348-0421.2006.tb03868.x · Cited by 150 · see citing works

Mannan-Binding Lectin-Associated Serine Protease (MASP)-1 Is Crucial for Lectin Pathway Activation in Human Serum, whereas neither MASP-1 nor MASP-3 Is Required for Alternative Pathway Function

Degn, S. E., Jensen, L., Hansen, A. G., Duman, D., Tekin, M., Jensenius, J. C., & Thiel, S. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1201736 · Cited by 150 · see citing works

Origin of the classical complement pathway: Lamprey orthologue of mammalian C1q acts as a lectin

Matsushita, M., Matsushita, A., Endo, Y., Nakata, M., Kojima, N., Mizuochi, T., & Fujita, T. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402180101 · Cited by 144 · see citing works

Cloning and Characterization of the Human Lectin P35 Gene and Its Related Gene

Endo, Y., Sato, Y., Matsushita, M., et al. (1996) · Genomics · doi:10.1006/geno.1996.0497 · Cited by 142 · see citing works

The Two Major Oligomeric Forms of Human Mannan-Binding Lectin: Chemical Characterization, Carbohydrate-Binding Properties, and Interaction with MBL-Associated Serine Proteases

Teillet, F., Dublet, B., Andrieu, J., et al. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.5.2870 · Cited by 135 · see citing works

Interactions between mannose-binding lectin and MASPs during complement activation by the lectin pathway

Wallis, R. (2006) · Immunobiology · doi:10.1016/j.imbio.2006.11.004 · Cited by 128 · see citing works

Human l ‐ficolin: plasma levels, sugar specificity, and assignment of its lectin activity to the fibrinogen‐like (FBG) domain

Le, Y., Lee, S. H., Kon, O. L., et al. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)00267-1 · Cited by 125 · see citing works

Collectin-11/MASP Complex Formation Triggers Activation of the Lectin Complement Pathway - The Fifth Lectin Pathway Initiation Complex

Ma, Y. J., Skjoedt, M., & Garred, P. (2012) · Journal of Innate Immunity · doi:10.1159/000345356 · Cited by 123 · see citing works

Interaction Properties of Human Mannan-Binding Lectin (MBL)-Associated Serine Proteases-1 and -2, MBL-Associated Protein 19, and MBL

Thielens, N. M., Cseh, S., Thiel, S., et al. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.8.5068 · Cited by 122 · see citing works

MASP-1, a Promiscuous Complement Protease: Structure of Its Catalytic Region Reveals the Basis of Its Broad Specificity

Dobó, J., Harmat, V., Beinrohr, L., Gyukity-Sebestyén, E., Závodszky, P., & Gál, P. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0901141 · Cited by 121 · see citing works

Carbohydrate Recognition Properties of Human Ficolins

Gout, E., Garlatti, V., Smith, D. F., Lacroix, M., Dumestre‐Pérard, C., Lunardi, T., Martin, L., Cesbron, J.-Y., Arlaud, G. J., Gaboriaud, C., et al. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.065854 · Cited by 119 · see citing works

Hakata Antigen, a New Member of the Ficolin/Opsonin p35 Family, Is a Novel Human Lectin Secreted into Bronchus/Alveolus and Bile

Akaiwa, M., Yae, Y., Sugimoto, R., Suzuki, S. O., Iwaki, T., Izuhara, K., & Hamasaki, N. (1999) · Journal of Histochemistry & Cytochemistry · doi:10.1177/002215549904700607 · Cited by 119 · see citing works

M‐ficolin, an Innate Immune Defence Molecule, Binds Patterns of Acetyl Groups and Activates Complement

Frederiksen, P. D., Thiel, S., Larsen, C. B., & Jensenius, J. C. (2005) · Scandinavian Journal of Immunology · doi:10.1111/j.1365-3083.2005.01685.x · Cited by 118 · see citing works

Characteristics and Biological Variations of M-Ficolin, a Pattern Recognition Molecule, in Plasma

Wittenborn, T. R., Thiel, S., Jensen, L., Nielsen, H. J., & Jensenius, J. C. (2009) · Journal of Innate Immunity · doi:10.1159/000218324 · Cited by 116 · see citing works

The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex

Budayova‐Spano, M., Lacroix, M., Thielens, N. M., Arlaud, G. J., Fontecilla‐Camps, J. C., & Gaboriaud, C. (2002) · The EMBO Journal · doi:10.1093/emboj/21.3.231 · Cited by 111 · see citing works

Human ficolin: cDNA cloning, demonstration of peripheral blood leucocytes as the major site of synthesis and assignment of the gene to chromosome 9

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Molecular Determinants of Oligomer Formation and Complement Fixation in Mannose-binding Proteins

Wallis, R., & Drickamer, K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.6.3580 · Cited by 108 · see citing works

A True Autoactivating Enzyme

Gál, P., Harmat, V., Kocsis, A., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m506051200 · Cited by 102 · see citing works

Stoichiometry of Complexes between Mannose-binding Protein and Its Associated Serine Proteases

Chen, C.-B., & Wallis, R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103539200 · Cited by 101 · see citing works

THE THREE‐DIMENSIONAL CONFORMATION OF γ M and γ A GLOBULIN MOLECULES

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Discrimination between host and pathogens by the complement system

Pangburn, M. K., Ferreira, V. P., & Cortés, C. (2008) · Vaccine · doi:10.1016/j.vaccine.2008.11.023 · Cited by 94 · see citing works

Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway

Møller-Kristensen, M., Thiel, S., Sjoholm, A., Matsushita, M., & Jensenius, J. C. (2006) · International Immunology · doi:10.1093/intimm/dxl131 · Cited by 94 · see citing works

Interaction of Mannose-binding Protein with Associated Serine Proteases

Wallis, R., & Dodd, R. B. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004030200 · Cited by 91 · see citing works

C-Reactive Protein: Structural Biology and Host Defense Function

Szalai, A. J., Agrawal, A., Greenhough, T. J., et al. (1999) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.1999.046 · Cited by 90 · see citing works

X-ray Structure of the Ca2+-binding Interaction Domain of C1s

Gregory, L., Thielens, N. M., Arlaud, G. J., Fontecilla-Camps, J. C., & Gaboriaud, C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305175200 · Cited by 88 · see citing works

The Structure of MBL-associated Serine Protease-2 Reveals that Identical Substrate Specificities of C1s and MASP-2 are Realized Through Different Sets of Enzyme–Substrate Interactions

Harmat, V., Gál, P., Kardos, J., Szilágyi, K., Ambrus, G., Végh, B. M., Náray‐Szabó, G., & Závodszky, P. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.07.014 · Cited by 86 · see citing works

Biosynthesis of human ficolin, an Escherichia coli‐binding protein, by monocytes: comparison with the synthesis of two macrophage‐specific proteins, C1q and the mannose receptor

Lu, J., Le, Y., Kon, O. L., et al. (1996) · Immunology · doi:10.1046/j.1365-2567.1996.d01-732.x · Cited by 85 · see citing works

Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2

Héja, D., Harmat, V., Fodor, K., Wilmanns, M., Dobó, J., Kékesi, K. A., Závodszky, P., Gál, P., & Pál, G. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.354332 · Cited by 84 · see citing works

Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components

Thiel, S., Jensen, L., Degn, S. E., Nielsen, H. J., Gál, P., Dobó, J., & Jensenius, J. C. (2012) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2012.04584.x · Cited by 84 · see citing works

Identification of the mouse H-ficolin gene as a pseudogene and orthology between mouse ficolins A/B and human L-/M-ficolins

Endo, Y., Liu, Y., Kanno, K., Takahashi, M., Matsushita, M., & Fujita, T. (2004) · Genomics · doi:10.1016/j.ygeno.2004.07.006 · Cited by 83 · see citing works

Localization of the Serine Protease-binding Sites in the Collagen-like Domain of Mannose-binding Protein

Wallis, R., Shaw, J. M., Uitdehaag, J. C. M., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400171200 · Cited by 81 · see citing works

Crystal Structure of the CUB1-EGF-CUB2 Domain of Human MASP-1/3 and Identification of Its Interaction Sites with Mannan-binding Lectin and Ficolins

Teillet, F., Gaboriaud, C., Lacroix, M., et al. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m803551200 · Cited by 77 · see citing works

The phylogeny of the complement system and the origins of the classical pathway

Dodds, A. W., & Matsushita, M. (2007) · Immunobiology · doi:10.1016/j.imbio.2006.11.009 · Cited by 75 · see citing works

Structural model of the collagen-like region of C1q comprising the kink region and the fibre-like packing of the six triple helices

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The X-ray Structure of Human Mannan-binding Lectin-associated Protein 19 (MAp19) and Its Interaction Site with Mannan-binding Lectin and L-ficolin

Gregory, L., Thielens, N. M., Matsushita, M., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402687200 · Cited by 71 · see citing works

Characterization of the Interaction Between L-Ficolin/P35 and Mannan-Binding Lectin-Associated Serine Proteases-1 and -2

Cseh, S., Vera, L., Matsushita, M., Fujita, T., Arlaud, G. J., & Thielens, N. M. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.10.5735 · Cited by 68 · see citing works

Which Came First, the Lectin/Classical Pathway or the Alternative Pathway of Complement?

Dodds, A. W. (2002) · Immunobiology · doi:10.1078/0171-2985-00137 · Cited by 68 · see citing works

Isolation and characterization of a thermolabile β-2 macroglycoprotein (‘thermolabile substance’ or ‘Hakata antigen’) detected by precipitating (auto) antibody in sera of patients with systemic lupus erythematosus

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Scavenger Receptor Collectin Placenta 1 (CL-P1) Predominantly Mediates Zymosan Phagocytosis by Human Vascular Endothelial Cells

Jang, S., Ohtani, K., Fukuoh, A., Yoshizaki, T., Fukuda, M., Motomura, W., Mori, K., Fukuzawa, J., Kitamoto, N., Yoshida, I., et al. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m807477200 · Cited by 65 · see citing works

Trivalent Recognition Unit of Innate Immunity System

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Two Oligomeric Forms of Plasma Ficolin Have Differential Lectin Activity

Ohashi, T., & Erickson, H. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.22.14220 · Cited by 64 · see citing works

Characterization of the Oligomer Structure of Recombinant Human Mannan-binding Lectin

Jensen, P., Weilguny, D., Matthiesen, F., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m412472200 · Cited by 62 · see citing works

Mannan-Binding Lectin: Structure, Oligomerization, and Flexibility Studied by Atomic Force Microscopy

Jensenius, H., Klein, D. C. G., van Hecke, M., et al. (2009) · Journal of Molecular Biology · doi:10.1016/j.jmb.2009.05.083 · Cited by 61 · see citing works

Semi-flexible joint in the C1q subunit of the first component of human complement

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Co-Complexes of MASP-1 and MASP-2 Associated with the Soluble Pattern-Recognition Molecules Drive Lectin Pathway Activation in a Manner Inhibitable by MAp44

Degn, S. E., Jensen, L., Olszowski, T., Jensenius, J. C., & Thiel, S. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1300780 · Cited by 61 · see citing works

Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation

Gingras, A. R., Girija, U. V., Keeble, A. H., et al. (2011) · Structure · doi:10.1016/j.str.2011.08.014 · Cited by 58 · see citing works

Identification of the Site of Human Mannan-Binding Lectin Involved in the Interaction with Its Partner Serine Proteases: The Essential Role of Lys55

Teillet, F., Lacroix, M., Thiel, S., et al. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.9.5710 · Cited by 55 · see citing works

Mannan-binding lectin (MBL)-mediated opsonization is enhanced by the alternative pathway amplification loop

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Interaction of mannan‐binding lectin with Trichinella spiralis glycoproteins, a possible innate immune mechanism

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Conformational Changes in Mannan-Binding Lectin Bound to Ligand Surfaces

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