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Cited by 6Facial Rejuvenation and Surgery TechniquesDermatologic Treatments and ResearchAcne and Rosacea Treatments and Effects

Assessment of current practices and perceived effectiveness of injectable polynucleotide for enlarged facial pores among cosmetic physicians: A survey-based evaluation

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Lee, Dagyeong, Choi, Hosung, Yoo, Kyounghun, Park, Young Jin, Park, Hyun Jun, Oh, Seung Min, Ji, Gun Hyon, Rah, Gong Chan +1 more·2024·Skin Research and Technology
DOI 10.1111/srt.13738PMC PMC11375025
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Abstract

Background: Polynucleotides stimulate collagen formation and are used clinically to enhance elasticity. In this study, we investigated current practices and perceived effectiveness of polynucleotide injection treatment for enlarged facial pores among cosmetic physicians. Materials and Methods: A survey was developed to investigate clinicians’ use and effectiveness of polynucleotides in the treatment of enlarged facial pores. This survey was distributed to clinicians at the Korean Aesthetic Surgery & Laser Society Autumn Symposium. Results: A total of 407 physicians who used polynucleotides for enlarged facial pores were enrolled in the survey. Polynucleotides were used by 75.7%, 87.7%, and 72.2% of physicians for enlarged facial pores caused by excessive sebum production, reduced elasticity, and acne, respectively. Among those users, 81.4%, 83.8%, and 76.8% in those same categories, respectively, responded that polynucleotides were “very effective” or “effective.” Furthermore, most clinicians combined polynucleotides with microneedle radiofrequency as energy‐based devices and with botulinum toxin as injection therapy. Conclusion: This study highlights the widespread use and perceived efficacy of polynucleotide injection among cosmetic physicians in the Republic of Korea for enlarged facial pores due to excessive sebum production, reduced elasticity, and acne. Positive feedback from practitioners supports the benefits of using polynucleotides in enlarged facial pore treatment.

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Authors
Lee, D., Choi, H., Yoo, K., Park, Y. J., Park, H. J., Oh, S. M., Ji, G. H., Rah, G. C., & Shin, D. W.
Affiliations
  • Hallym University Dongtan Sacred Heart Hospital (KR)
  • Piena Aesthetic Clinic Seoul Republic of Korea
  • Lumi Clinic Seoul Republic of Korea
  • Obliv Clinic Incheon Republic of Korea
  • Maylin Clinic Seoul Republic of Korea
  • Gangnam ON Clinic Seoul Republic of Korea
  • Yonseidongan Clinic Seoul Republic of Korea
  • Robbin Clinic Seoul Republic of Korea
  • Samsung Medical Center (KR)
Corresponding author
  • Rah, Gong Chan
  • Shin, Dong Wook
ORCID
Venue
Skin Research and Technology
Publisher
Wiley
Published
2024-09
Volume
30
Issue
9
Pages
e13738-e13738
ISSN
  • 0909-752X (ISSN-L)
  • 1600-0846
DOI
10.1111/srt.13738
PMC
PMC11375025
OpenAlex
W4402284734
Cited by
6
References
1
Citations by year
2026: 3 · 2025: 2 · 2024: 1
FWCI
2.43
Type
journal article
Language
en
Open access
Licence
Locations
  • Skin Research and Technology (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Dermatology › Facial Rejuvenation and Surgery Techniques
  • Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
  • Health Sciences › Medicine › Dermatology › Acne and Rosacea Treatments and Effects
Keywords
perceived treatment effectiveness, collagen stimulation, skin elasticity, sebum production, acne, botulinum toxin, energy-based devices
MeSH terms
Dermal Fillers, Acne Vulgaris, Adult, Cosmetic Techniques, Face, Female, Humans, Male, Middle Aged, Practice Patterns, Physicians', Polynucleotides, Surveys and Questionnaires, Skin Aging, Republic of Korea

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