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Cited by 532

The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.

Control of ACh sensitivity by muscle activity in the rat

Open access
Lømo, T., Rosenthal, Jean·1972·The Journal of Physiology
DOI 10.1113/jphysiol.1972.sp009764
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Abstract

1. Rat soleus and extensor digitorum longus (EDL) muscles were examined following complete blockade of sciatic nerve impulses with anaesthetics or diphtheria toxin for periods up to 14 days. 2. Muscles showed atrophy equivalent to that seen after similar periods of denervation. 3. Nerve blockade appeared to have little or no effect on neuromuscular transmission when tested by stimulation beyond the block. Normal spontaneous miniature end‐plate potentials were present. 4. Nerve impulse blockade caused the entire muscle membrane to become sensitive to iontophoretically applied acetylcholine. 5. The increase in sensitivity in soleus could be prevented by chronic nerve stimulation distal to the region of block. 6. Tenotomy, of 5‐12 days duration, which produced atrophy, had no effect on the sensitivity of soleus to acetylcholine. 7. Chronic direct stimulation of denervated soleus or EDL muscles could prevent the usual denervation supersensitivity, or cause it to decline towards normal once it had appeared. However, the sensitivity of the end‐plate region remained normal.

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Metadata

Authors
Lømo, T., & Rosenthal, J.
Venue
The Journal of Physiology
Publisher
Wiley
Published
1972-03
Volume
221
Issue
2
Pages
493-513
ISSN
  • 0022-3751 (ISSN-L)
  • 1469-7793
DOI
10.1113/jphysiol.1972.sp009764
OpenAlex
W2013830080
Cited by
532
References
14
FWCI
20.31
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Control of ACh sensitivity by muscle activity in the rat. https://app.cochat.ai/papers/10.1113/jphysiol.1972.sp009764
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Lømo, T., & Rosenthal, J. (1972). Control of ACh sensitivity by muscle activity in the rat. The Journal of Physiology. https://doi.org/10.1113/jphysiol.1972.sp009764

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.