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Cited by 367

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

The effect of adenosine on the release of the transmitter from the phrenic nerve of the rat

Open access
Ginsborg, B. L., Hirst, G. D. S.·1972·The Journal of Physiology
DOI 10.1113/jphysiol.1972.sp009916
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Abstract

1. The action of adenosine on neuromuscular transmission has been studied on the rat phrenic nerve—diaphragm preparation. 2. Adenosine (0·025–10 m M) reversibly reduced the quantum content of end‐plate potentials and the frequency of miniature end‐plate potentials to about half the control values in preparations in which transmission was blocked with high Mg 2+ and/or low Ca 2+ concentrations. Where transmission was blocked with tubocurarine, the amplitude of end‐plate potentials was reduced to about half the control values by adenosine. 3. In solutions with very low Ca 2+ concentrations (no added Ca 2+ and 1 m M‐EGTA) adenosine had a smaller effect on the frequency of miniature end‐plate potentials. 4. The effect of adenosine (0·025 and 0·05 m M) was abolished by theophylline (1·8 m M). 5. The results are discussed in relation to the increase in cyclic AMP in brain slices caused by adenosine and the abolition of this effect by theophylline (Sattin & Rall, 1970).

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Crossref · 10.1113/jphysiol.1972.sp009916

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Metadata

Authors
Ginsborg, B. L., & Hirst, G. D. S.
Venue
The Journal of Physiology
Publisher
Wiley
Published
1972-08
Volume
224
Issue
3
Pages
629-645
ISSN
  • 0022-3751 (ISSN-L)
  • 1469-7793
DOI
10.1113/jphysiol.1972.sp009916
OpenAlex
W2159767473
Cited by
367
References
12
FWCI
4.97
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The effect of adenosine on the release of the transmitter from the phrenic nerve of the rat. https://app.cochat.ai/papers/10.1113/jphysiol.1972.sp009916
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Ginsborg, B. L., & Hirst, G. D. S. (1972). The effect of adenosine on the release of the transmitter from the phrenic nerve of the rat. The Journal of Physiology. https://doi.org/10.1113/jphysiol.1972.sp009916

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.