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Cited by 539

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Digital mammographic tumor classification using transfer learning from deep convolutional neural networks

Open access
Huynh, Benjamin Q., Li, Hui, Giger, Maryellen L.·2016·Journal of Medical Imaging

Abstract

Convolutional neural networks (CNNs) show potential for computer-aided diagnosis (CADx) by learning features directly from the image data instead of using analytically extracted features. However, CNNs are difficult to train from scratch for medical images due to small sample sizes and variations in tumor presentations. Instead, transfer learning can be used to extract tumor information from medical images via CNNs originally pretrained for nonmedical tasks, alleviating the need for large datasets. Our database includes 219 breast lesions (607 full-field digital mammographic images). We compared support vector machine classifiers based on the CNN-extracted image features and our prior computer-extracted tumor features in the task of distinguishing between benign and malignant breast lesions. Five-fold cross validation (by lesion) was conducted with the area under the receiver operating characteristic (ROC) curve as the performance metric. Results show that classifiers based on CNN-extracted features (with transfer learning) perform comparably to those using analytically extracted features [area under the ROC curve [Formula: see text]]. Further, the performance of ensemble classifiers based on both types was significantly better than that of either classifier type alone ([Formula: see text] versus 0.81, [Formula: see text]). We conclude that transfer learning can improve current CADx methods while also providing standalone classifiers without large datasets, facilitating machine-learning methods in radiomics and precision medicine.

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Metadata

Authors
Huynh, B. Q., Li, H., & Giger, M. L.
Venue
Journal of Medical Imaging
Published
2016-08-22
Volume
3
Issue
3
Pages
034501
ISSN
2329-4302 (ISSN-L)
OpenAlex
W2510224130
Cited by
539
References
9
FWCI
37.62
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Digital mammographic tumor classification using transfer learning from deep convolutional neural networks. https://app.cochat.ai/papers/10.1117/1.jmi.3.3.034501
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Huynh, B. Q., Li, H., & Giger, M. L. (2016). Digital mammographic tumor classification using transfer learning from deep convolutional neural networks. Journal of Medical Imaging. https://doi.org/10.1117/1.jmi.3.3.034501

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.