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Predicting Stereoselective Disposition of Carvedilol in Adult and Pediatric Chronic Heart Failure Patients by Incorporating Pathophysiological Changes in Organ Blood Flows-A Physiologically Based Pharmacokinetic Approach
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“A two-fold error range (0.5–2.0) was used as a criterion to evaluate the predicted performance for PK parameters [50,51,52].”
From Predicting Food–Drug Interactions between Piperine and CYP3A4 Substrate Drugs Using PBPK Modeling (2024) · cites this paper as [52]
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Cites
Age-predicted maximal heart rate revisited
Tanaka, H., Monahan, K. D., & Seals, D. R. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)01054-8 · Cited by 3,775 · cited 2×
“Compared with adults, children have higher frequency of heart rate (Tanaka et al., 2001; Fleming et al., 2011) and a higher drug CL due to higher percentage of liver weight in relation to body weight (Noda et al.”
BackgroundAltered intestinal function in patients with chronic heart failure
Sandek, A., Bauditz, J., Swidsinski, A., Buhner, S., Weber-Eibel, J., von Haehling, S., Schroedl, W., Karhausen, T., Doehner, W., Rauchhaus, M., et al. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.07.016 · Cited by 661
Johnson, T. N., Rostami-Hodjegan, A., & Tucker, G. T. (2006) · Clinical Pharmacokinetics · doi:10.2165/00003088-200645090-00005 · Cited by 530
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Cited by
Predicting Food–Drug Interactions between Piperine and CYP3A4 Substrate Drugs Using PBPK Modeling
Lin, F., Hu, Y., Zhang, Y., Zhao, L., Zhong, D., & Liu, J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252010955 · Cited by 20
Metadata
- Authors
- Rasool, M. F., Khalil, F., & Läer, S.
- Venue
- Drug Metabolism and Disposition
- Publisher
- Elsevier BV
- Published
- 2016-07
- Volume
- 44
- Issue
- 7
- Pages
- 1103-1115
- ISSN
- 0090-9556
- Cited by
- 19
- References
- 3
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
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