Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD+?

Cantó, Carles, Auwerx, Johan·2012·Pharmacological Reviews

DOI 10.1124/pr.110.003905

Cites (240)

Items 201–240 of 240

Endothelial Nitric Oxide Synthase (eNOS) Knockout Mice Have Defective Mitochondrial β-Oxidation
Gouill, Eric Le, Jimenez, Maria, Binnert, Christophe, Jayet, Pierre-Yves, Thalmann, Sebastien, Nicod, Pascal, Scherrer, Urs, Vollenweider, Peter · 2007 · Diabetes
CK2 Is the Regulator of SIRT1 Substrate-Binding Affinity, Deacetylase Activity and Cellular Response to DNA-Damage
Hyeog Kang, Jaewon Jung, Myung K. Kim, Jay H. Chung · 2009 · PLoS ONE
Mitochondrial impairment in p53-deficient human cancer cells
S. Zhou · 2003 · Mutagenesis
Liver Steatosis and Increased ChREBP Expression in Mice Carrying a Liver Specific SIRT1 Null Mutation under a Normal Feeding Condition
Ruihong Wang, Cuiling Li, Chu‐Xia Deng · 2010 · International Journal of Biological Sciences
Novel targeted therapeutics: inhibitors of MDM2, ALK and PARP
Yuan Yuan, Yu-Min Liao, Chung-Tsen Hsueh, Hamid Mirshahidi · 2011 · Journal of Hematology & Oncology
The Evolutionarily Conserved Longevity Determinants HCF-1 and SIR-2.1/SIRT1 Collaborate to Regulate DAF-16/FOXO
Gizem Rizki, Terri Iwata, Ji Li, Christian G. Riedel, Colette Lafontaine Picard, Max Jan, Coleen Tara Murphy, Siu Sylvia Lee · 2011 · PLoS Genetics
Syntheses of Nicotinamide Riboside and Derivatives: Effective Agents for Increasing Nicotinamide Adenine Dinucleotide Concentrations in Mammalian Cells
Tianle Yang, Noel Yan‐Ki Chan, Anthony A. Sauve · 2007 · Journal of Medicinal Chemistry
SIRT1 Transcription Is Decreased in Visceral Adipose Tissue of Morbidly Obese Patients with Severe Hepatic Steatosis
Cíntia dos Santos Costa, Thaís Ortiz Hammes, Francieli Rohden, Rogério Margis, Josiane Woutheres Bortolotto, Alexandre Vontobel Padoin, Cláudio Corá Mottin, Regina Maria Vieira da Costa Guaragna · 2009 · Obesity Surgery
Sir2 and calorie restriction in yeast: A skeptical perspective
Matt R. Kaeberlein, R. Wilson Powers · 2007 · Ageing Research Reviews
The effect of gamma radiation and neocarzinostatin of NAD and ATP levels in mouse leukaemia cells
Patricia M. Goodwin, P.J. Lewis, M. I. DAVIES, CHRISTOPHER J. SKIDMORE, Sydney Shall · 1978 · Biochimica et Biophysica Acta (BBA) - General Subjects
Peroxisome Proliferator-activated Receptor (PPAR)-2 Controls Adipocyte Differentiation and Adipose Tissue Function through the Regulation of the Activity of the Retinoid X Receptor/PPARγ Heterodimer
Péter Bai, Sander M. Houten, Aline Huber, Valérie Schreiber, 光博渡辺, Borbála Kiss, Gilbert de MURCIA, Johan H. Auwerx, Josiane Ménissier‐de Murcia · 2007 · Journal of Biological Chemistry
SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity
Rutanen, Jarno, Yaluri, Nagendra, Modi, Shalem, Pihlajamäki, Jussi, Vänttinen, Markku, Itkonen, Paula, Kainulainen, Sakari, Yamamoto, Hiroyasu, Lagouge, Marie, Sinclair, David A. et al. · 2010 · Diabetes
The Management of Nicotinamide and Nicotinic Acid in the Mouse
Patrick B Collins, Sterling Chaykin · 1972 · Journal of Biological Chemistry
Large Supplements of Nicotinic Acid and Nicotinamide Increase Tissue NAD+ and Poly(ADP-Ribose) Levels but Do Not Affect Diethylnitrosamine-Induced Altered Hepatic Foci in Fischer-344 Rats
Tammy M. Jackson, Jean M. Rawling, Bill D. Roebuck, James B. Kirkland · 1995 · Journal of Nutrition
Ancient Roots Forced into Modern Pots
James Edward McClellan · 2002 · Science
MST1 Promotes Apoptosis through Regulating Sirt1-dependent p53 Deacetylation
Fang Yuan, Qi Xie, Junbing Wu, Yujie Bai, Beibei Mao, Yongli Dong, Wenzhi Bi, Guangju Ji, Wufan Tao, Yan Wang et al. · 2011 · Journal of Biological Chemistry
PPAR.BETA./.DELTA. regulates the human SIRT1 gene transcription via Sp1
Mizuho Okazaki, Yasumasa Iwasaki, Mitsuru Nishiyama, Takafumi Taguchi, Makoto Tsugita, Shuichi Nakayama, Machiko Kambayashi, Kozo Hashimoto, Yoshio Terada · 2010 · Endocrine Journal
dSir2 and Dmp53 interact to mediate aspects of CR-dependent life span extension in D. melanogaster
Johannes H. Bauer, Siti Nur Sarah Morris, Cheng-Yi Chang, Thomas Flatt, Jason G. Wood, Stephen L. Helfand · 2008 · Aging
Extended-release niacin raises adiponectin and leptin
Sabine Westphal, Katrin Borucki, Elena Taneva, Ruma Makarova, Claus H. Luley · 2006 · Atherosclerosis
Sirt7-dependent inhibition of cell growth and proliferation might be instrumental to mediate tissue integrity during aging.
Olesya Vakhrusheva, Daniela Braeuer, Z Liu, Thomas W Braun, Eva Bober · 2008 · PubMed
The CD38/cyclic ADP-ribose system: A topological paradox
Antonio DE FLORA, Lucrezia Guida, Luisa Franco, Elena Zocchi · 1997 · The International Journal of Biochemistry & Cell Biology
Niacin Status, NAD Distribution and ADP-Ribose Metabolism
James B. Kirkland · 2009 · Current Pharmaceutical Design
Adenine nucleotide diphosphates: emerging second messengers acting via intracellular Ca2+ release
Thomas Patrick Dousa, Eduardo N. Chini, Kelly W. Beers · 1996 · American Journal of Physiology-Cell Physiology
Molecular modeling of the GABAC receptor ligand-binding domain
Neil J. Harrison, Sarah C. R. Lummis · 2005 · Journal of Molecular Modeling
Carboxy-terminal phosphorylation of SIRT1 by protein kinase CK2
Barbara Zschoernig, Ulrich Mahlknecht · 2009 · Biochemical and Biophysical Research Communications
Correction: Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic ß Cells
Laura Bordone, Maria Carla Motta, Frédéric Picard, Ashley S. Robinson, Ulupi S. Jhala, Javier Apfeld, Thomas McDonagh, Madeleine E. Lemieux, Michael McBurney, Akos Szilvasi et al. · 2006 · PLoS Biology
Small RNA Regulators of Gene Expression
Joel R. Neilson, Phillip A. Sharp · 2008 · Cell
Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1
Aswin Mangerich, Nadja Herbach, Benjamin Hanf, Arthur Fischbach, Oliver Popp, María Moreno‐Villanueva, Oliver T. Bruns†, Alexander Bürkle · 2010 · Mechanisms of Ageing and Development
Correction: A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice
Jamie L. Barger, Tsuyoshi Kayo, James M. Vann, Edward B. Arias, Jelai Wang, Timothy A. Hacker, Ying Wang, Daniel Raederstorff, Jason D. Morrow, Christiaan Leeuwenburgh et al. · 2008 · PLoS ONE
Interference between PARPs and SIRT1: a novel approach to healthy ageing?
Carles Cantó, Johan H. Auwerx · 2011 · Aging
Longevity hits a roadblock
David B. Lombard, Scott D. Pletcher, Carles Cantó, Johan H. Auwerx · 2011 · Nature
Digestion and Absorption of NAD by the Small Intestine of the Rat
Carol J. Gross, LaVell M. Henderson · 1983 · Journal of Nutrition
Peroxisome Proliferator-Activated Receptor γ Coactivator-1α, as a Transcription Amplifier, Is Not Essential for Basal and Hormone-Induced Phosphoenolpyruvate Carboxykinase Gene Expression
Birger Herzog, Robert K. Hall, Xiaohui L. Wang, Mary E. Waltner-Law, Daryl K. Granner · 2004 · Molecular Endocrinology
Levels of nicotinamide adenine dinucleotide in extracellular body fluids of pigs may be growth-limiting for Actinobacillus pleuropneumoniae and Haemophilus parasuis.
Terence O'Reilly, Donald F. Niven · 2003 · PubMed
Short-term adenosine monophosphate-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside treatment increases the sirtuin 1 protein expression in skeletal muscle.
M. Suwa, Hiroshi Nakano, Z. Radák, S. Kumagai · 2011 · Metabolism: Clinical and Experimental
Design, synthesis and biological characterization of novel inhibitors of CD38
Min Dong, Yuan-Qi Si, Shuang-Yong Sun, Xiaoping Pu, Zhen-Jun Yang, Liangren Zhang, Lihe Zhang, Fung Ping Leung, Connie Mo Ching Lam, Anna Ka‐Yee Kwong et al. · 2011 · Organic & Biomolecular Chemistry
Kinetic competence of the cADP-ribose‒CD38 complex as an intermediate in the CD38/NAD+ glycohydrolase-catalysed reactions: implication for CD38 signalling
Céline Cakir‐Kiefer, Hélène Muller‐Steffner, Norman J. Oppenheimer, Francis J. Schuber · 2001 · Biochemical Journal
Mechanism-Based Inhibitors of CD38: A Mammalian Cyclic ADP-Ribose Synthetase
Anthony A. Sauve, Vern L. Schramm · 2002 · Biochemistry
Kinetic competence of the cADP-ribose–CD38 complex as an intermediate in the CD38/NAD+ glycohydrolase-catalysed reactions: implication for CD38 signalling
Céline Cakir‐Kiefer, Hélène Muller‐Steffner, Norman J. Oppenheimer · 2001 · Biochemical Journal
Efficacy of controlled-release niacin in treatment of metabolic syndrome: Correlation to surrogate markers of atherosclerosis, vascular reactivity, and inflammation
Christopher S. Vaccari, Sameer H. Nagamia, Martin Thoenes, 朝彦小口, Ramadan Hammoud, Bobby V. Khan · 2007 · Journal of clinical lipidology