Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 To Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution

Cited by (314)

Items 201–300 of 314

1. STAT3 promotes cytoplasmic-nuclear translocation of RNA-binding protein HuR to inhibit IL-1β-induced IL-8 production
   Jiangwen Long, Zhao Wang, Yangen Xiang, Yufei Wang, Wei Xiang, Xueting Liu, Manli Jiang, Yinghui Song, Jinyue Hu · 2024 · International Immunopharmacology
2. Expression of miR‐135a‐5p and its target gene JAK2 in spermatozoa of patients with asthenozoospermia
   Weiwei Li, Lei Zhang, Xiurong Yin · 2021 · Andrologia
3. Activated Src requires Cadherin-11, Rac, and gp130 for Stat3 activation and survival of mouse Balb/c3T3 fibroblasts
   Hanad Adan, Stephanie Guy, Rozanne Arulanandam, Mulu Geletu, Juliet M. Daniel, Leda H. Raptis · 2022 · Cancer Gene Therapy
4. Phytochemicals Targeting Inflammatory Pathways in Alcohol-Induced Liver Disease: A Mechanistic Review
   Swati Tirunal Achary, Prerna Gupta, Apoorva Rajput, Wanphidabet Sohkhia, Srinivasa Reddy Bonam, Bidya Dhar Sahu · 2025 · Pharmaceuticals
5. Rewired type I IFN signaling is linked to age-dependent differences in COVID-19
   Lev Petrov, Sophia Brumhard, Sebastian Wisniewski, Philipp Georg, David Hillus, Anna Luisa Hiller, Rosario Astaburuaga-García, Nils Blüthgen, Emanuel Wyler, Katrin Vogt et al. · 2025 · Cell Reports Medicine
6. Targeted blockade of extracellular vesicles-mediated profibrotic vicious circle using EVs-based dual-drug delivery system to prevent liver fibrosis
   Jie Sun, Yi Shen, Xiaoze Wang, Ruoting Men, Xian Xing, Linling Lv, Fan Yang, Mengyi Shen, Yanyi Zheng, Xiaoli Fan et al. · 2025 · Journal of Nanobiotechnology
7. Network pharmacology to explore the novel anti-inflammatory mechanism of naringenin in intestinal ischemia/reperfusion injury
   Min Hou, Yanshun Wang, Suheng Chen · 2025 · Frontiers in Immunology
8. Profiling of mouse and human liver diseases identifies targets for therapeutic treatment of autoimmune hepatitis
   Monica Centa, Christelle Thermidor, Maria Isabel Fiel, Konstantina Alexandropoulos · 2023 · Clinical Immunology
9. Fibroblast growth factor 10 alleviates LPS-induced acute lung injury by promoting recruited macrophage M2 polarization
   Nana Feng, Yufan Li, Feng Guo, Juan Song, Lu Wang, Miao Li, Kaijing Gao, Xiao-Cen Wang, Dejie Chu, Yuan-Lin Song et al. · 2024 · Inflammation
10. Deciphering the Interlinked CXCR4-Mediated Feedback Loop Among Signaling Pathways in Diabetic Wound Healing
    Sandhanam Kuppusamy, Bedanta Bhattacharjee, Damanbhalang Rynjah, Pratap Kalita, Saikat Sen, Raja Chakraborty · 2024 · Current Diabetes Reviews
11. Data-driven projections of candidate enhancer-activating SNPs in immune regulation
    Markus Hoffmann, Tiago André Gonçalves Vaz, Shreeti Chhatrala, Lothar G. Hennighausen · 2025 · BMC Genomics
12. Qingfei Litan decoction alleviated Klebsiella pneumoniae-induced pneumonia by targeting the TLR4/MyD88/NF-κB axis via miR-146a-5p
    Ruojun Wei, Ziyuan Zeng, Sheng Chen · 2025 · Journal of Ethnopharmacology
13. Serum JAK/STAT profile is related to the IL expression but not with the outcome in pancreatic adenocarcinoma patients
    Livia Petrusel, Maria Ilies, Daniel‐Corneliu Leucuta, Ioana Rusu, Andrada Seicean, Cristina Adela Iuga, Radu Seicean · 2021 · Cellular and Molecular Biology
14. Update on Structure and Function of SH2 Domains: Mechanisms and Emerging Targeting Strategies
    Moses M. Kasembeli, Jorge Rodas, David John Tweardy · 2025 · International Journal of Molecular Sciences
15. BRUCE liver-KO enhances MASLD/MASH development in the steatotic PTEN-KO background by impairing mitochondrial metabolism and activating STAT3
    Lixiao Che, Camille Stevenson, David R. Plas, Jiang Wang, Chunying Du · 2025 · Cell Death and Disease
16. HDAC6 deficiency exacerbates atherosclerosis via STAT3-K685 acetylation-mediated CD36/SR-A upregulation in macrophages
    Wenqing Wang, Yue Jiang, Xuan Pan, Dong Chen, Hui Yang, WANG Pan, Mingjie Pan, Bin Wang · 2025 · Cell Death and Disease
17. JAK2/STAT3-dependent regulation of MDM4/MDM2-p53 signaling in methotrexate-induced ferroptosis and nephrotoxicity
    Y. Cheng, M. Zhao, Yujia Zhang, Maobai Liu, Limei Zhao · 2026 · Archives of Pharmacal Research
18. Pre-cachectic changes in amino acid homeostasis precede activation of eIF2α signaling in the liver at the onset of C26 cancer-induced cachexia
    Ghita Chaouki, Laurent Parry, Cyrielle Vituret, Céline Jousse, Martin Leremboure, Céline Bourgne, Laurent Mosoni, Yoann Delorme, Mehdi Djelloul-Mazouz, Julien Hermet et al. · 2025 · iScience
19. YWHAG promotes the progression of lung adenocarcinoma through the JAK2/STAT3 pathway
    Hongmei Zheng, Yaoxiang Tang, Hongjing Zang · 2025 · Cancer Cell International
20. Role of FGF15 in Hepatic Surgery in the Presence of Tumorigenesis: Dr. Jekyll or Mr. Hyde?
    Albert Caballeria-Casals, Marc Micó-Carnero, Carlos Rojano-Alfonso, Cristina Maroto-Serrat, Araní Casillas-Ramírez, Ana I. Álvarez‐Mercado, Jordi Gracia‐Sancho, Carmen Peralta · 2021 · Cells
21. STAT3-mediated effects of methyltransferase inhibitor 5-aza-2'-deoxycytidine on preeclampsia.
    Xiaoli Zhang, Gang Wang, Hui Li, Xiangming Jiang, Xiaoyong Zhao · 2021 · PubMed Central
22. Blockade of interleukin-6 receptor attenuates apoptosis and modulates the inflammatory response in Mycoplasma pneumoniae infected A549 cells.
    Wei Fang, Jingyu Huang, Jun Wang · 2022 · PubMed
23. Anti-Cancer Mechanisms of Diarylpentanoid MS17 (1,5-Bis(2-hydroxyphenyl)-1,4-pentadiene-3-one) in Human Colon Cancer Cells: A Proteomics Approach
    Kha Wai Hon, Syafiq Asnawi Zainal Abidin, Faridah Abas · 2024 · International Journal of Molecular Sciences
24. p27 specifically decreases in squamous carcinoma, and mediates NNK ‐induced transformation of human bronchial epithelial cells
    Minggang Peng, Hao Meng, Jingjing Wang, Mengxin Guo, Tengda Li, Xiaohui Qian, Ruifan Chen, Honglei Jin, Chuanshu Huang · 2024 · Journal of Cellular and Molecular Medicine
25. Ginsenoside Rg5 alleviates hypoxia-induced myocardial apoptosis by targeting STAT3 to promote Tyr705 phosphorylation
    Fei Li, Yihao Wang, Yi-hao Wang et al. · 2025 · Chinese Medicine
26. HSP90 inhibitors beyond oncology: optimization and mechanism insights in non-oncological diseases
    Xingyu Yin, Huangliang Shu, Danni Wang, Qidong You, Qiuyue Zhang, Lei Wang · 2025 · Drug Discovery Today
27. Chrysin Alters Hypothalamic Levels of Proteins Related to Appetite and Sweet Taste Preferences in Fructose-Fed Rats
    Lurdes Santos, Hugo Osório, Nelson Andrade, Fátima Martel · 2025 · Journal of Nutrition
28. JAK-STAT pathway in hematological malignancies: Achievements, challenges and future perspectives
    Bing Pan, Kaixin Shi, Yuxiao Li, Xiaobo Wang, Cheng Song, Qi Zhang, Li Li · 2026 · Biomedicine & Pharmacotherapy
29. Molecular mechanisms in endometriosis: linking JAK/STAT pathway, ferroptosis, and microbial dysbiosis
    Humaira Shah, Naguib Salleh, Mukhri Hamdan, Nelli Giribabu · 2026 · Molecular Biology Reports
30. Targeting IL-6 Signaling Pathways for Musculoskeletal Disorders Treatment: Risks and Benefits
    Aisha Muthanna Shanshal, Raghda Hisham Aljorani, Saad Abdulrahman Hussain · 2023 · Al-Rafidain Journal of Medical Sciences
31. Structure-Guided Discovery of Adenosine Triphosphate-Competitive Casein Kinase 2 Inhibitors
    Shivani P. Patel, Vivek Kumar Vyas, Manmohan Sharma, Manjunath D. Ghate · 2023 · Future Medicinal Chemistry
32. Perindopril Dampens Cd-induced Nephrotoxicity by Suppressing Inflammatory Burden, Ang II/Ang 1–7, and Apoptosis Signaling Pathways
    Zuhair M. Mohammedsaleh, Emad H. M. Hassanein, Fares E.M. Ali · 2023 · Biological Trace Element Research
33. The critical role of signal transducers and activators of transcription-3 in the proliferation of vascular smooth muscle cells
    Shuai Li, Chan Liu · 2023 · Journal of Holistic Integrative Pharmacy
34. Trilobolide-6-O-isobutyrate exerts anti-tumor effects on cholangiocarcinoma cells through inhibiting JAK/STAT3 signaling pathway
    Haoxuan Zhang, Rui Fan, Qian-En Chen · 2024 · Heliyon
35. Remote Kidney and Liver Injury After Transplantation of Lung Allografts in an Allogeneic Mouse Model
    Marcin L. Sander, Volker Eulenburg, Tatsuo Maeyashiki, Jae–Hwi Jang, Sarah Dorothea Müller, Sebastian N. Stehr, Wolfgang Jungraithmayr, Tobias Piegeler · 2024 · Transplantation Proceedings
36. Proton pump inhibitors use and risk of type 2 diabetes mellitus: correlation analysis, prediction model construction, and key genes identification
    Cuilv Liang, Yin Zhang · 2025 · Frontiers in Pharmacology
37. Potential of Alkaloids from Zanthoxylum nitidum var. tomentosum in Treating Rat Rheumatoid Arthritis Model and Validation of Molecular Mechanisms
    Yuanle Shen, Linghui Zou, Yinggang Zeng, Ting Xia, Zhenjie Liu, Kaili Hu, Liuping Wang, Jianfang Feng · 2025 · Current Issues in Molecular Biology
38. The molecular mechanisms and targeting strategies of transcription factors in cholangiocarcinoma
    Jiao Wang, Fujing Ge, Tao Yuan, Meijia Qian, Fangjie Yan, Bo Yang, Qiaojun He, Hong Zhu · 2022 · Expert Opinion on Therapeutic Targets
39. P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy
    Quanpeng Qiu, Gang Guo, Xiaolong Guo, Xiake Hu, Tianyu Yu, Gaixia Liu, Haowei Zhang, Yinnan Chen, Junjun She · 2023 · Biomedicines
40. MODERN MARKERS OF OSTEODYSMETABOLIC SYNDROME
    Viktoriia M. Plaksa · 2023 · Актуальні проблеми сучасної медицини Вісник Української медичної стоматологічної академії
41. Modulating the Biliverdin Reductase (BVR)/ERK1/2 Axis to Attenuate Oxidative Stress in Rat Arterial Rings
    Kuldeepak Sharma, Mateja Škufca Sterle, Hugon Možina · 2024 · Iranian journal of pharmaceutical research
42. Formononetin Mediates α7nAChR to Inhibit Macrophage Polarization and Ameliorate Atherosclerotic Plaque
    Li Du, Shirong Li, Qiansong He · 2025 · Current Topics in Medicinal Chemistry
43. Mesenchymal stromal cells alleviate pulmonary arterial hypertension by suppressing pulmonary arterial adventitial fibroblast activation and extracellular matrix remodeling via the SOCS3/STAT3 pathway
    Jiaojiao Wang, Jing Jin, Mengni Zhang · 2026 · Stem Cell Research & Therapy
44. Computational Identification of FDA‐Approved Drugs as STAT3 Dimerization Inhibitors for Therapeutic Applications
    Muhammad Yasir, Jinyoung Park, Jongseon Choe, Wanjoo Chun · 2026 · ChemistrySelect
45. The JAK/STAT Pathway in Cancer: From Molecular Mechanisms to Clinical Applications
    Yixing Liao, Qi Wei, Hongjun Song, Hao Zeng, Chang Qi, Yunchang Meng, Yuanyuan Zhang, Yuanyuan Zhang, Weimin Li, Yalun Li et al. · 2026 · MedComm – Oncology
46. [Effects of Janus kinase/signal transduction and activator of transcription 3 pathway inhibitor in skeletal muscle function in severely burned rats and its mechanism].
    Hailiang Bai, Hongjie Duan, Chaochao Chen, L Y Liu, Yanfang Wu, Songmei Han, X T Wang · 2021 · PubMed Central
47. New STAT3 inhibitor through biotransformation of celastrol by Streptomyces olivaceus CICC 23628
    Yaqian Feng, Peipei Chen, Chuyue Huang, Hailan Chen, Ruolan Fan, Lu Wang, Shaohua Xu, Wen Xu, Zhimin Fan, Wei Xu · 2022 · Arabian Journal of Chemistry
48. Synthesis and biological evaluation of novel isoxazoloquinone derivatives as potent STAT3-targeting antipsoriasis agents
    Ling Chen, Shuaiwen Zhu, Yuanzhu Xie et al. · 2024 · Bioorganic Chemistry
49. Elevated RBP4 in Subclinical Ketosis Cows Inhibits Follicular Granulosa Cell Proliferation and Steroid Hormone Synthesis
    Chang Zhao, Ruru Xu, Weizhe Yan · 2024 · Animals
50. Synthesis, biological evaluation, and molecular docking of ent -sauchinone-based amide derivatives with potential anti-invasion and anti-migration activities
    Yanjun He, Di Xiao, Qi‐Zhe Gong · 2025 · Natural Product Research
51. COVID-19 Associated Inflammatory Pathways
    Lujun Chen · 2021 · American Journal of Biomedical Science & Research
52. Guanine nucleotide-binding protein 2, GNBP2, accelerates the progression of clear cell renal cell carcinoma via regulation of STAT3 signaling transduction pathway
    Qingfei Cao, Jiaji Ma, Weitao Li · 2022 · Genes & Genomics
53. Analysis of the Potential Relationship between Aging and Pulmonary Fibrosis Based on Transcriptome
    San Fu, Xiaoyan Tang, Yiming Xu, Xianrui Song, Xiuhui Qian, Yingying Hu, Mian Zhang · 2022 · Life
54. Pipeline Therapeutics
    Rob Leland Shaver, Michelle Anne Lowes, Noah I. Goldfarb · 2021 · Elsevier eBooks
55. Anti-Gastric Cancer Effect of Purified Omphalia Lapidescens Protein via Regulating the JAK/STAT3 Signaling Pathway
    Wenjun Xu, Zhongxia Lu, Man Hei Cheung · 2020 · Research Square
56. Atractylenolide I Inhibits Triple-Negative Breast Cancer Cell Proliferation and Promotes Apoptosis via Blocking the Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Signaling Pathway
    Zhiye Hao, Zheng Pan, Wei Qian · 2022 · Journal of Biomaterials and Tissue Engineering
57. Stat3 is a mediator for TGFβ1 regulating bromodomain protein 4 and cross-talks with Smad3 signaling and Egr-1 in hepatic stellate cell
    Feifan Xu, Sidan Lu, Feifan Zhao, Nachuan Pan, Xin Jia, Yajun Zhou · 2022 · Research Square
58. Short-term exposure to dimethyl fumarate (DMF) inhibits LPS-induced IκBζ expression in macrophages: implications for the pharmacological activity of DMF
    Yong Zhang, Jingshu Tang, Yujun Zhou, Xiong Xiao, Qiuyu Chen, Hongyue Wang, Jiaqi Lan, Lei Wu, Ying Peng · 2022 · Research Square
59. MPN-Related Mutations and JAK2 Inhibitor Therapy
    骏 杨 · 2023 · Advances in Clinical Medicine
60. Hcy regulates SIRT1-STAT3 phosphorylation by upregulating WWP2 expression and induce VSMCs proliferation, migration, and phenotypic switch.
    Xiuyu Wang, Xing Ma, Yue Zeng, Smritee Pokharel, minghao zhang · 2023 · Research Square
61. Pathomechanism of Liver Fibrosis and Mesenchymal Stem Cells in its Resolution Process
    Anggun Lestary Husein, Isabella Kurnia Liem · 2023 · Open Access Macedonian Journal of Medical Sciences
62. PREDIKSI PERAN CURCUMINOID PADA CURCUMA LONGA SEBAGAI INHIBITOR GSK-3 TERHADAP PERTUMBUHAN DENTIN TERSIER
    Naila Robbaniyya Fithriyya, Hanifah Nur Syafa, Dwi cinthya Financia et al. · 2021 · Medical and Health Journal
63. Network pharmacology-based analysis: Fufang Xiongdan Diyanye—clinical response and mechanism of action in the treatment of acute bacterial conjunctivitis
    Shanshan Wang, Chulong HUANG, Fang Li · 2020 · Journal of Holistic Integrative Pharmacy
64. WITHDRAWN: Microbiota mitigate Caddy-Induced Lung Injury via Modulating Survivin, Matrix Metalloproteinase-9 and Janus Kinase-2 Gene Expression
    Rehab M. Abdel Megeed, Mai O. Kadry · 2023 · Journal of Trace Elements and Minerals · Retracted
65. Identification and validation of PANoptosis and autophagy-related molecular characterization in ulcerative colitis
    Jiali Lu, Fei Li, Mei Ye · 2023 · Research Square
66. SHP-1 interacts with NFκB1 to inhibit its phosphorylation and nuclear translocation to suppress excessive bacterial inflammation
    Ning Ning Wang, Suxu Tan, Muyuan Wang · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
67. French Paradox: A Role for Akt Activation
    Ferenc Gallyas, Ildikó Bock-Marquette, Kálmán Tóth, Róbert Halmosi · 2024 · Advances in biochemistry in health and disease
68. The Molecular Signature Related to Local Inflammatory and Immune Response in Canine Cutaneous Hypersensitivity Reactions: A Preliminary Study
    Camilla Capaccia, Francesco Ciancabilla, Ilaria Porcellato, Chiara Brachelente, Massimo Zerani, Margherita Maranesi, Gabriella Guelfi · 2024 · Current Issues in Molecular Biology
69. BRUCE liver-deficiency potentiates MASLD/MASH in PTEN liver-deficient background by impairment of mitochondrial metabolism in hepatocytes and activation of STAT3 signaling in hepatic stellate cells
    Lixiao Che, Camille K. Stevenson, David R. Plas, Jiang Wang, Chunying Du · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
70. Rewired type I IFN signaling is linked to age-dependent differences in COVID-19
    Lev Petrov, Sophia Brumhard, Sebastian Wisniewski, Philipp Georg, David Hillus, Anna Luisa Hiller, Rosario Astaburuaga-García, Nils Blüthgen, Emanuel Wyler, Katrin Vogt et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
71. Cardiomyocyte-enriched USP20 ameliorates pathological cardiac hypertrophy by targeting STAT3-CARM1 axis
    Deling Yin, Lingfeng Zhong, Shanshan Dai, Fan Yu, Guo‐Ping Shi, Qinyan Gong, Yucong Zhang, Jingsi Duan, Zhengyin Lou, Zhixuan Tang et al. · 2024 · Research Square
72. Vitiligo: Etiology and Pathophysiology
    Rawan Almutairi · 2025 · IntechOpen eBooks
73. Analysis of SFTS pathogenesis based on single-cell RNA sequencing of monocytes
    Yin Zhang, Mengtao Gong, Qianqian Yang, Yangyang Jin, Yuanhong Xu · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
74. Cutaneous toxicities secondary to STAT3 inhibition: A retrospective case series
    Kevin Paul Lee, Apostolia Maria Tsimberidou, Abhijit Chakraborty, Anisha B. Patel · 2025 · JAAD Case Reports
75. A Novel Molecule Zyz311 Derivatized from Carvacrol Ameliorates Dss-Induced Colitis in Mice Via Inhibiting Jak2/Stat3
    Fuyuan Zhang, Jianghong Cai, Xiangming Zhu, Rong Fu, Zhongxiao Lin, Yu Yang Huang, Yiling Chen, Wei Qi, Zhiyu Wang, Qian Ding et al. · 2025 · SSRN Electronic Journal
76. A Novel Molecule Zyz311 Derivatized from Carvacrol Ameliorates Dss-Induced Colitis in Mice Via Inhibiting Jak2/Stat3
    Fuyuan Zhang, Jianghong Cai, Xiangming Zhu, Rong Fu, Zhongxiao Lin, Yu Yang Huang, Yiling Chen, Wei Qi, Zhiyu Wang, Qian Ding et al. · 2025 · SSRN Electronic Journal
77. Stem Cells from Human Exfoliated Deciduous Teeth Improve Motor Function after Sciatic Nerve Injury Through Suppression of Inflammation
    Takahiro Oyama, Koji Osuka, Yusuke Nishimura et al. · 2025 · Stem Cells and Development
78. Effect of Lachnum YM156 Polyphenol on STAT3/COX-2 Signal Pathway and Gut Microbiota in Mice with N-Nitrosodiethylamine-Induced Hepatic Injury
    Tingting Chen, Dong Liu, Ming Ye · 2025 · Food Technology and Biotechnology
79. Artesunate attenuates pulmonary fibrosis by suppressing fibroblast senescence through inhibition of the STAT3/p53 signaling pathway
    Jianyi Ding, Zhile Chen, Jiaqin Yu, Yangjun Xu, Ting Zhu, Bin Wang, Zhuyang Feng, Xinhuo Li, Xiumin Qian, Bingqian Jin et al. · 2025 · Toxicology and Applied Pharmacology
80. Additional file 2 of β-Arrestin2-biased Drd2 agonist UNC9995 alleviates astrocyte inflammatory injury via interaction between β-arrestin2 and STAT3 in mouse model of depression
    Liu, Yang, Nanshan Song, Yao, Hang, Jiang, Siyuan, Yueping Wang, Zheng, Ying, Zhou, Yuanzhang, Ding, Jianhua, Hu, Gang, Lu, Ming · 2022 · Figshare
81. Additional file 1 of A hybrid nanopharmaceutical for specific-amplifying oxidative stress to initiate a cascade of catalytic therapy for pancreatic cancer
    Liu, Fan, Qinyanqiu Xiang, Luo, Yuanli · 2024 · Figshare
82. Additional file 1 of Dynamic alterations in metabolomics and transcriptomics associated with intestinal fibrosis in a 2,4,6-trinitrobenzene sulfonic acid-induced murine model
    Wu, Jinzhen, Zhenyi Tian, Zhuang, Xiaoduan · 2024 · Figshare
83. Additional file 1 of β-Arrestin2-biased Drd2 agonist UNC9995 alleviates astrocyte inflammatory injury via interaction between β-arrestin2 and STAT3 in mouse model of depression
    Liu, Yang, Nanshan Song, Yao, Hang, Jiang, Siyuan, Yueping Wang, Zheng, Ying, Zhou, Yuanzhang, Ding, Jianhua, Hu, Gang, Lu, Ming · 2022 · Figshare
84. MD2 suppresses anaplastic thyroid Cancer progression by reprogramming macrophages via USP15-mediated FHL1 Deubiquitination
    Qilu Fang, Neng Lv, Jia Wang · 2026 · International Immunopharmacology
85. Estrogens in Liver Regeneration: From Molecular Mechanisms to Clinical Translation
    Thiago Oliveira, Gleisy Kelly Neves Gonçalves · 2026 · IntechOpen eBooks
86. Ph-chromosome-negative myeloproliferative neoplasms: clonal dynamics are the name of the game
    Mohammadamin Noorafrooz, Ramin Noorafrooz, Giovanni Barosi, Robert Peter Gale · 2026 · Blood Reviews
87. Liver Kinase B1 in CD11c + Cells Inhibits Fibrosis in Chronic Pancreatitis via the Oncostatin M Signaling
    Wenqing Zhang, Shan Guo, Yu Zhang et al. · 2026 · Advanced Science
88. Investigating the molecular signature of reactive astrocytes mediated by the JAK2- STAT3 pathway using different omics : transcriptomics and proteomics insights
    Miriam Riquelme‐Perez · 2023 · theses.fr (ABES)
89. Sgp130Fc regulates IL-6/JAK2/STAT3 trans-signaling pathway in rat vocal fold fibroblast activation
    Mengdie Gao, Xueyan Li, Haizhou Wang, Yuhong Lin, Rong Hu, Wen Xu · 2026 · Experimental Cell Research
90. Development and evaluation of a predictive biomarker model based on the niacin flush pathway for differentiating schizophrenia and bipolar disorder
    Chin‐Jen Wu, Jin-Jia Lin, Chih‐Chun Huang et al. · 2026 · Schizophrenia Research
91. Thermo-responsive astaxanthin-polymeric nanocarriers targeting STAT3-RIPK1 mediated PANoptosome formation for neuroprotection in retinal injury
    Rong Rong, Jiamiao Liu, Ganghao Liang, Yixian Liu, Xiaobo Xia · 2026 · Advanced Composites and Hybrid Materials
92. Viral Mechanisms and Drug Influences on Janus Kinase/Signal Transducers and Activators of Transcription (JAK/STAT) Pathway in Human Coronaviruses Infection: A Systematic Review
    Esimebia Adjovi Amegashie, Ruth Oyawole Sikeola, Caleb Koranteng Kwayisi‐Darkwah, Gabriel Atampugre Atampugbire, Emmanuel Ayitey Tagoe, Elijah Paintsil, Kwasi Torpey, Osbourne Quaye · 2026 · Health Science Reports
93. Microplastics induce osteoarthritis by modulating chondrocyte inflammation and disrupting TGF-β signaling in mesenchymal stem cells
    Kainong Sun, Shuting Zhou, Meng Yang et al. · 2026 · Journal of Advanced Research
94. Novel insights into triple-negative breast cancer heterogeneity, prognosis, and treatment response based on matrix stiffness: a combined single-Cell and transcriptome analysis
    Wenjie Shi, Haofeng Wang, Yingxin Guan · 2026 · Frontiers in Oncology
95. Caloric restriction reprograms skeletal muscle molecular pathways in non-human primates: potential relevance to human aging biology
    Jayanta Kumar Das, Nirad Banskota, Stefano Donegà, Nader Shehadeh, Yulan Piao, Nathan Price, Julie A. Mattison, Julián Candia, Rafael de Cabo, Luigi Ferrucci · 2026 · Skeletal Muscle
96. Mechanism of Cucurbitacin B Targeting ZNF70 / NLRP3 Axis Against Inflammation‐Associated Colorectal Cancer
    Shen Cao, Yi Tai, Yuhan Wang · 2026 · Phytotherapy Research
97. Skeletal muscle mass and inflammation-based prognostic score as prognostic factors in oral cancer
    E. Yamasaki, S. Yamasaki, M. Naito · 2026 · International Journal of Oral and Maxillofacial Surgery
98. Bone Morphogenetic Protein Type IA Receptor Mimetic Peptide CK2.1 Activates Chondrogenesis in Chondrocytes from Osteoarthritis Patients
    Kailey DeGeorge, Venu Pandit, Daniel R. Halloran · 2026 · Cytology and Genetics
99. Timosaponin A1 exerts antitumor effect against osteosarcoma by targeting JAK2/STAT3 signaling pathway
    Jia Shi, Yixuan Xu, Tongtong Liu · 2026 · The International Journal of Biochemistry & Cell Biology
100. Integrated In Vivo and In Silico Approaches for Targeting JAK2/STAT3/SOCS3: Repurposing Boeravinone B and Resveratrol as Chemopreventive Agents in Colon Cancer
     Shabnoor Iqbal, Usman Khan · 2026 · Assay and Drug Development Technologies