Carbon Monoxide: Endogenous Production, Physiological Functions, and Pharmacological Applications

Tissue variant effects of heme inhibitors on the mouse cytochrome c oxidase gene expression and catalytic activity of the enzyme complex

Vijayasarathy, C., Damle, S., Lenka, N., & Avadhani, N. G. (1999) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1999.00843.x · Cited by 38

Carbon monoxide stimulates a potassium-selective current in rabbit corneal epithelial cells

Rich, A. J., Farrugia, G., & Rae, J. L. (1994) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1994.267.2.c435 · Cited by 38

Occurrence and putative hormone regulatory function of a constitutive heme oxygenase in rat pancreatic islets

Henningsson, R. N., Alm, P., & Lundquist, I. (1997) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1997.273.2.c703 · Cited by 37

Estrogen Increases Endothelial Carbon Monoxide, Heme Oxygenase 2, and Carbon Monoxide-Derived cGMP by a Receptor-Mediated System

Tschugguel, W., Stonek, F., Zhegu, Z., Dietrich, W., Schneeberger, C., Stimpfl, T., Waldhoer, T., Vycudilik, W., & Huber, J. C. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.86.8.3833 · Cited by 36

Effect of nitric oxide and carbon monoxide on uterine contractility during human and rat pregnancy

Longo, M., Jain, V., Vedernikov, Y. P., Saade, G. R., Goodrum, L. A., Facchinetti, F., & Garfield, R. E. (1999) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(99)70336-4 · Cited by 36

Therapeutic Applications of Human Heme Oxygenase Gene Transfer and Gene Therapy

Abraham, N. G. (2003) · Current Pharmaceutical Design · doi:10.2174/1381612033453758 · Cited by 36

Differential effect of cobalt protoporphyrin on distributions of heme oxygenase in renal structure and on blood pressure in SHR.

Abraham, N. G., Botros, F. T., Rezzani, R., Rodella, L. F., Bianchi, R., & Goodman, A. I. (2002) · PubMed · Cited by 35

Heme oxygenase-1 induction by nitric oxide in RAW 264.7 macrophages is upregulated by a cyclo-oxygenase-2 inhibitor

Alcaraz, M. J. (2001) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(01)00112-x · Cited by 35

A Comparative Study of the Effects of Nitric Oxide and Carbon Monoxide on the in vivo Release of Gonadotropin-Releasing Hormone and Neuropeptide Y from Rat Hypothalamus during the Estradiol-Induced Luteinizing Hormone Surge: Estimation by Push-Pull Perfusion

Kohsaka, A., Watanobe, H., Kakizaki, Y., & Suda, T. (1999) · Neuroendocrinology · doi:10.1159/000054425 · Cited by 34

Cytochrome P 450-linked monooxygenase: involvement in the lamb ductus arteriosus

Coceani, F., Hamilton, N., Labuc, J., & Olley, P. M. (1984) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1984.246.4.h640 · Cited by 34

Prolonged Clinical Use of a Heme Oxygenase Inhibitor: Hematological Evidence for an Inducible but Reversible Iron-Deficiency State

Kappas, A., Drummond, G. S., & Galbraith, R. A. (1993) · PEDIATRICS · doi:10.1542/peds.91.3.537 · Cited by 33

Alterations in Heme Oxygenase/Carbon Monoxide System in Pulmonary Arteries in Hypertension

Ndisang, J. F., & Wang, R. T. (2003) · Experimental Biology and Medicine · doi:10.1177/15353702-0322805-27 · Cited by 32

Heme oxygenase type 2 participates in the development of chronic inflammatory and neuropathic pain

Li, X., & Clark, J. D. (2003) · Journal of Pain · doi:10.1054/jpai.2003.18 · Cited by 31

Heme Oxygenase as an Intrinsic Defense System in Vascular Wall : Implication against Atherogenesis

Ishikawa, K., & Maruyama, Y. (2001) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat1994.8.63 · Cited by 31

Heme Oxygenase Activity in Term Human Placenta

McLaughlin, B. E., Hutchinson, J. M., Graham, C. H., Smith, G. N., Marks, G. S., Nakatsu, K., & Brien, J. F. (2000) · Placenta · doi:10.1053/plac.2000.0574 · Cited by 30

Modulation of Corneal Heme Oxygenase Expression by Oxidative Stress Agents

Neil, T. K., Stoltz, R. A., JIANG, S., Schwartzman, M. L., Dunn, M. W., Levere, R. D., KAPPAS, A., & Abraham, N. G. (1995) · Journal of Ocular Pharmacology and Therapeutics · doi:10.1089/jop.1995.11.455 · Cited by 30

Interaction of Selective Amino Acid Residues of KCa Channels with Carbon Monoxide

Wang, R. T., & Wu, L. (2003) · Experimental Biology and Medicine · doi:10.1177/15353702-0322805-09 · Cited by 30

In vivo role of heme oxygenase in ischemic coronary vasodilation

Nishikawa, Y., Stepp, D. W., Merkus, D., Jones, D. W., & Chilian, W. M. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00671.2003 · Cited by 28

Resonance Raman studies of the carbonmonoxy form of catalase Evidence for and effects of phenolate ligation

Hu, S., & Kincaid, J. R. (1992) · FEBS Letters · doi:10.1016/0014-5793(92)81492-5 · Cited by 26

Generation of Cyclic Guanosine Monophosphate by Heme Oxygenases in the Human Testis—A Regulatory Role for Carbon Monoxide in Sertoli Cells?1

Middendorff, R., Kumm, M., Davidoff, M. S., Holstein, A. F., & Müller, D. (2000) · Biology of Reproduction · doi:10.1095/biolreprod63.2.651 · Cited by 26

Adrenocorticotropin induces heme oxygenase-1 expression in adrenal cells

Pomeraniec, Y., Grion, N., Gadda, L., Pannunzio, V. G., Podesta, E. J., & Cymeryng, C. B. (2004) · Journal of Endocrinology · doi:10.1677/joe.0.1800113 · Cited by 26

Mitochondrial oxygenation of carbon monoxide

Young, L. J., & Caughey, W. S. (1986) · Biochemical Journal · doi:10.1042/bj2390225 · Cited by 26

Pathobiochemistry of CO poisoning

Young, L. J., & Caughey, W. S. (1990) · FEBS Letters · doi:10.1016/0014-5793(90)80436-m · Cited by 25

Effects of prenatal exposure to low concentrations of carbon monoxide on sexual behaviour and mesolimbic dopaminergic function in rat offspring

Cagiano, R., Ancona, D. M. R., Cassano, T., Tattoli, M., Trabace, L., & Cuomo, V. (1998) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0702143 · Cited by 24

Heme Oxygenase-1 against Vascular Insufficiency: Roles of Atherosclerotic Disorders

Ishikawa, K. (2003) · Current Pharmaceutical Design · doi:10.2174/1381612033453767 · Cited by 24

Chronic morphine exposure and the expression of heme oxygenase type 2

Li, X., & Clark, J. D. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(99)00254-5 · Cited by 23

Hypoxic contraction of small pulmonary arteries from normal and endotoxemic rats: fundamental role of NO

Terraz, S., Baechtold, F., Renard, D., et al. (1999) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1999.276.4.h1207 · Cited by 23

Carbon monoxide induces murine thymocyte apoptosis by a free radical-mediated mechanism

Turcanu, V., Dhouib, M., Gendrault, J. L., & Poindron, P. (1998) · Cell Biology and Toxicology · doi:10.1023/a:1007416505088 · Cited by 22

Heme Oxygenase in the Rat Ovary: Immunohistochemical Localization and Possible Role in Steroidogenesis

Alexandreanu, I. C., & Lawson, D. M. (2003) · Experimental Biology and Medicine · doi:10.1177/153537020322800108 · Cited by 22

A Protective Role for Heme Oxygenase Expression in Pancreatic Islets Exposed to Interleukin-1

Ye, J. (1998) · Endocrinology · doi:10.1210/en.139.10.4155 · Cited by 22

Carbon Monoxide Stimulates mrp2-Dependent Excretion of Bilirubin-IXα into Bile in the Perfused Rat Liver

NORIMIZU, S., Kudo, A., Kajimura, M., Ishikawa, K., Taniai, H., Yamaguchi, T., Fujii, K., Arii, S., Nimura, Y., & Suematsu, M. (2003) · Antioxidants and Redox Signaling · doi:10.1089/152308603768295195 · Cited by 21

Biliverdin IX is an endogenous inhibitor of soluble guanylyl cyclase

Koglin, M., & Behrends, S. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(02)01056-0 · Cited by 21

Co-operation of the transcription factor hepatocyte nuclear factor-4 with Sp1 or Sp3 leads to transcriptional activation of the human haem oxygenase-1 gene promoter in a hepatoma cell line

Takahashi, S., MATSUURA, N., Kurokawa, T., Takahashi, Y. K., & Miura, T. (2002) · Biochemical Journal · doi:10.1042/bj20020819 · Cited by 20

Effects of Phenylarsine Oxide on Expression of Heme Oxygenase-1 Reporter Constructs in Transiently Transfected Cultures of Chick Embryo Liver Cells

Shan, Y., Lambrecht, R. W., Lu, T. H., & Bonkovsky, H. L. (1999) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1999.1490 · Cited by 20

Changes in peripheral nervous system activity produced in rats by prenatal exposure to carbon monoxide

Carratù, M. R., Renna, G. M., Giustino, A., Salvia, M. A. D., & Cuomo, V. (1993) · Archives of Toxicology · doi:10.1007/bf01973698 · Cited by 19

RNA polymerase II inhibitor, 5,6-dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) causes erythroleukemic differentiation and transcriptional activation of erythroid genes

Hensold, J. O., Barth, D., & Stratton, C. A. (1996) · Journal of Cellular Physiology · doi:10.1002/(sici)1097-4652(199607)168:1<71::aid-jcp9>3.0.co;2-5 · Cited by 15

Different mechanisms underlying the stimulation of KCa channels by nitric oxide and carbon monoxide

Wu, L., Cao, K., Lu, Y., & Wang, R. T. (2002) · Journal of Clinical Investigation · doi:10.1172/jci200215316 · Cited by 13

Dysregulation of endogenous carbon monoxide and nitric oxide production in patients with advanced ischemic or nonischemic cardiomyopathy

Seshadri, N., Dweik, R. A., Laskowski, D. M., Pothier, C. E., Rodriguez, L. L., Young, J. B., & Migrino, R. Q. (2003) · The American Journal of Cardiology · doi:10.1016/s0002-9149(03)00890-7 · Cited by 12

Evidence for a Functional Link between the Heme Oxygenase-Carbon Monoxide Pathway and Corticotropin-Releasing Hormone Release from Primary Cultures of Human Trophoblast Cells1

Navarra, P., Miceli, F., Tringali, G., Minici, F., Pardo, M. G., Lanzone, A., Mancuso, S., & Apa, R. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.1.7091 · Cited by 11

Differential response of testicular and ovarian heme oxygenase activity to metal ions

Maines, M. D., & Kutty, R. K. (1983) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(83)90278-3 · Cited by 11

Inhibitors of nitric oxide synthase block carbon monoxide-induced increases in cGMP in retina

Cao, L., & Eldred, W. D. (2003) · Brain Research · doi:10.1016/s0006-8993(03)03346-8 · Cited by 11

Evidence for a Functional Link between the Heme Oxygenase-Carbon Monoxide Pathway and Corticotropin-Releasing Hormone Release from Primary Cultures of Human Trophoblast Cells

Navarra, P. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.86.1.317 · Cited by 11

Carbon monoxide-induced cardiac hypertrophy is not reduced by alpha- or beta-blockade in the rat

Penney, D. G., & Formolo, J. M. (1993) · Toxicology · doi:10.1016/0300-483x(93)90179-v · Cited by 9

Carbon monoxide-binding properties of the cytochromeboquinol oxidase complex inEscherichia coliare changed by copper deficiency in continuous culture

Ciccognani, D. T., Hughes, M., & Poole, R. K. (1992) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1992.tb05278.x · Cited by 9

Effects of heme oxygenase system on the cyclooxygenase in the primary cultured hypothalamic cells

Lee, H.-U., Lee, H.-J., Park, H. Y., Lee, S., Jang, C., & Lee, S. (2001) · Archives of Pharmacal Research · doi:10.1007/bf02975174 · Cited by 6

Studies on the Development of Carbon Monoxide-Releasing Molecules

Motterlini, R., Foresti, R., & Green, C. J. (2001) · CRC Press eBooks · doi:10.1201/9781420041019.sec3 · Cited by 6

Carbon Monoxide and Vascular Smooth Muscle Cell Growth

Durante, W. (2001) · CRC Press eBooks · doi:10.1201/9781420041019.ch3 · Cited by 6

Angiogenic Gene Therapy With Vascular Endothelial Growth Factor - Hope or Hype?

Dulak, J., & Józkowicz, A. (2002) · European surgery. Supplement/European surgery · doi:10.1046/j.1563-2563.2002.02028.x · Cited by 2

Pharmacological and Clinical Aspects of Heme Oxygenase

Abraham, N. G., & Kappas, A. (2008) · Pharmacological Reviews · doi:10.1124/pr.107.07104 · Cited by 1,115

Reactive Oxygen Species in the Regulation of Synaptic Plasticity and Memory

Massaad, C. A., & Klann, E. (2011) · Antioxidants & Redox Signaling · doi:10.1089/ars.2010.3208 · Cited by 635

Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide

Whiteman, M., Li, L., Kostetski, I., Chu, S. H., Siau, J. L., Bhatia, M., & Moore, P. K. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.02.154 · Cited by 377

Heme Degradation and Vascular Injury

Belcher, J. D., Beckman, J. D., Balla, G., Balla, J., & Vercellotti, G. (2010) · Antioxidants & Redox Signaling · doi:10.1089/ars.2009.2822 · Cited by 257

Carbon Monoxide Inhibits L-type Ca2+ Channels via Redox Modulation of Key Cysteine Residues by Mitochondrial Reactive Oxygen Species

Scragg, J. L., Dallas, M. L., Wilkinson, J. A., Varadi, G., & Peers, C. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m803037200 · Cited by 133