Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors

Dominy, Stephen S., Lynch, Casey, Ermini, Florian, Benedyk, Malgorzata, Marczyk, Agata, Konradi, Andrei, Nguyen, Mai, Haditsch, Ursula +18 more·2019·Science Advances

Cited by (1,002)

Items 601–700 of 1,002

  1. Porphyromonas gingivalis Gingipains-Mediated Degradation of Plasminogen Activator Inhibitor-1 Leads to Delayed Wound Healing Responses in Human Endothelial Cells
    Liting Song, Hiroyuki Tada, Takashi Nishioka, Eiji Nemoto, Takahisa Imamura, Jan Potempa, Changyi Li, Kenji Matsushita, Shunji Sugawara · 2021 · Journal of Innate Immunity
  2. Microglia and microglial-based receptors in the pathogenesis and treatment of Alzheimer’s disease
    Zhiyu Wang, Donald Fredric Weaver · 2022 · International Immunopharmacology
  3. A dual functional polypeptide with antibacterial and anti-inflammatory properties for the treatment of periodontitis
    Yuexiang Li, Yunfeng Ma, Jianan Yu, Cancan Li, Da Yu, Ruoxi Dai, Quanli Li, Chris Ying Cao · 2023 · International Journal of Biological Macromolecules
  4. Mesenchymal stem cell-derived extracellular vesicles for treatment of bone loss within periodontitis in pre-clinical animal models: a meta-analysis
    Huan Zhou, Yan-Xin Qi, Chunhui Zhu, Ang Li, Dandan Pei · 2023 · BMC Oral Health
  5. Vitamin D decreases Porphyromonas gingivalis internalized into macrophages by promoting autophagy
    Li Na Niu, Shuangshuang Chen, Xue Yang, Chunliang Ma, Chunling Pan, Hongyan Wang, Qian Li, Fengxue Geng, Xiaolin Tang · 2020 · Oral Diseases
  6. Expression Profiling and Cell Type Classification Analysis in Periodontitis Reveal Dysregulation of Multiple lncRNAs in Plasma Cells
    Donglei Wu, Peng Zhou, Fengdi Cao, Zhengshen Lin, Defeng Liang, Xincai Zhou · 2020 · Frontiers in Genetics
  7. Diurnal and eating-associated microbial patterns revealed via high-frequency saliva sampling
    Yichen Hu, Amnon Amir, Xiaochang Huang, Yan Li, Shi Wei Huang, Elaine Wolfe, Sophie J. Weiss, Rob D. Knight, Zhenjiang Zech Xu · 2022 · Genome Research
  8. Qué hay acerca de las personas en la ciencia regional
    Torsten Hägerstrand · 1991 · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
  9. Poor Oral Health and Risk of Incident Dementia: A Prospective Cohort Study of 425,183 Participants
    Rui-Qi Zhang, Ya‐Nan Ou, Shu‐Yi Huang, Yuzhu Li, Yuyuan Huang, Ya-Ru Zhang, Shi-Dong Chen, Qiang Dong, Jianfeng Feng, Wei Cheng et al. · 2022 · Journal of Alzheimer s Disease
  10. Linking Periodontitis with Inflammatory Bowel Disease through the Oral–Gut Axis: The Potential Role of Porphyromonas gingivalis
    Xinyi Huang, Yilin Li, Jun Zhang, Qiang Feng · 2024 · Biomedicines
  11. Activatable Photoacoustic Probe for Imaging Infection: Gold Nanorod Dissociation In Vivo Reports Bacterial Protease Activity
    Maurice Retout, Victor Lepeintre, Lubna Amer, Wonjun Yim, Jesse V. Jokerst · 2025 · ACS Nano
  12. Linkage of circadian rhythm disruptions with Alzheimer's disease and therapeutic interventions
    Kishore Madhamanchi, Jianhua Zhang, Girish Chandra Melkani · 2025 · Acta Pharmaceutica Sinica B
  13. Periodontitis-induced neuroinflammation triggers IFITM3-Aβ axis to cause alzheimer’s disease-like pathology and cognitive decline
    Lingwenyao Kong, Juanjuan Li, Lu Gao, Yonggang Zhao, Weixian Chen, Xumeng Wang, Songlin Wang, Fu Wang · 2025 · Alzheimer s Research & Therapy
  14. An agent-based model to investigate microbial initiation of Alzheimer’s via the olfactory system
    Shalini Sundar, Carly Battistoni, Ryan McNulty, Fernando Morales, Jonathan M. Gorky, Henry C. Foley, Prasad Dhurjati · 2020 · Theoretical Biology and Medical Modelling
  15. Multitarget Approach to Drug Candidates against Alzheimer’s Disease Related to AChE, SERT, BACE1 and GSK3β Protein Targets
    Larisa B. Ivanova, Mati M. Karelson, Dimitar A. Dobchev · 2020 · Molecules
  16. A quantitative framework reveals traditional laboratory growth is a highly accurate model of human oral infection
    Gina R. Lewin, Kendall S. Stocke, Richard John Lamont, Marvin Whiteley · 2022 · Proceedings of the National Academy of Sciences
  17. Herpes simplex virus alters Alzheimer's disease biomarkers ‐ A hypothesis paper
    Oliver Goldhardt, Robert Freiberger, Tobias F. Dreyer, Luisa Willner, Igor Y. Yakushev, Marion Ortner, Hans Förstl, Janine Diehl‐Schmid, Esther Milz, Josef Priller et al. · 2022 · Alzheimer s & Dementia
  18. The emerging role of the microbiome in Alzheimer's disease
    Caroline Wasén, Ella Simonsen, Millicent N. Ekwudo, Martin R. Profant, Laura M. Cox · 2022 · International review of neurobiology
  19. ProBDNF signaling is involved in periodontitis-induced depression-like behavior in mouse hippocampus
    Yingxue Li, Xiaoyue Guan, Yani He, Xiangbin Jia, Lifei Pan, Yuting Wang, Yue Han, Rui Zhao, Jianmin Yang, Tiezhou Hou · 2022 · International Immunopharmacology
  20. Interplay between Porphyromonas gingivalis Hemophore-Like Protein HmuY and Kgp/RgpA Gingipains Plays a Superior Role in Heme Supply
    Michał Śmiga, Paulina Ślęzak, Mateusz Maciej Wagner, Teresa Olczak · 2023 · Microbiology Spectrum
  21. Revisiting Alpha-Synuclein Pathways to Inflammation
    Patrícia Lyra, Vanessa Machado, Silvia Rota, К. Ray Chaudhuri, João Botelho, José João Mendes · 2023 · International Journal of Molecular Sciences
  22. Abnormal blood microbiota profiles are associated with inflammation and immune restoration in HIV/AIDS individuals
    Xiaoyan Guo, Zerui Wang, Mengmeng Qu, Yuntian Guo, Minrui Yu, Weiguo Hong, Chao Zhang, Xing Fan, Jin‐Wen Song, Ruonan Xu et al. · 2023 · mSystems
  23. Restoring periodontal tissue homoeostasis prevents cognitive decline by reducing the number of Serpina3nhigh astrocytes in the hippocampus
    Zongshan Shen, Shuhong Kuang, Yong Zhang, Jiayao Chen, Shuting Wang, Cong‐Fei Xu, Yunjia Huang, Min Zhang, Shuheng Huang, Jun Wang et al. · 2023 · The Innovation
  24. Gingipain-carrying outer membrane vesicles from Porphyromonas gingivalis cause barrier dysfunction of Caco-2 cells by releasing gingipain into the cytosol
    Saori Nonaka, Rin Okamoto, Yui Katsuta, Shiori Kanetsuki, Hiroshi Nakanishi · 2024 · Biochemical and Biophysical Research Communications
  25. Lipopolysaccharide-Binding Protein, Soluble CD14, and the Long-Term Risk of Alzheimer’s Disease: A Nested Case-Control Pilot Study of Older Community Dwellers from the Three-City Cohort
    Perrine André, Cécilia Samieri, Charline Buisson, Jean‐François Dartigues, Catherine Helmer, Fabienne Laugerette, Catherine Féart · 2019 · Journal of Alzheimer s Disease
  26. Emerging intraoral biosensors
    Jianwu Wang, Jing Yu, Ting Wang, Chengcheng Li, Yan Qiu Wei, Xuliang Deng, Xiaodong Chen · 2019 · Journal of Materials Chemistry B
  27. Blood brain barrier inflammation and potential therapeutic role of phytochemicals
    Welcome, Menizibeya O. · 2020 · PharmaNutrition
  28. In Situ Raman Study of Neurodegenerated Human Neuroblastoma Cells Exposed to Outer-Membrane Vesicles Isolated from Porphyromonas gingivalis
    Giuseppe Pezzotti, Tetsuya Adachi, Hayata Imamura, Davide Redolfi‐Bristol, Keiji Adachi, Toshiro Yamamoto, Narisato Kanamura, Elia Marin, Wenliang Zhu, Toshihisa Kawai et al. · 2023 · International Journal of Molecular Sciences
  29. Chronic Oral Inoculation of Porphyromonas gingivalis and Treponema denticola Induce Different Brain Pathologies in a Mouse Model of Alzheimer Disease
    Giuseppe D. Ciccotosto, Ali I Mohammed, Rita A. Paolini, Elly Bijlsma, Su Toulson, James A. Holden, Eric Charles Reynolds, Stuart G. Dashper, Catherine A. Butler · 2024 · The Journal of Infectious Diseases
  30. Oral Fusobacterium nucleatum resists the acidic pH of the stomach due to membrane erucic acid synthesized via enoyl-CoA hydratase-related protein FnFabM
    Xiaocong Li, Shipeng Zhang, Hua-Fang Sheng, Yan Zhen, Buling Wu, Zhuang Li, Dingqiang Chen, Hongwei Zhou · 2025 · Journal of Oral Microbiology
  31. Porphyromonas gingivalis-induced periodontitis promotes neuroinflammation and neuronal loss associated with dysfunction of the brain barrier
    Yiting Jiang, Lina Xu, Xuri Zhao, Hui Shen, Che Qiu, Zhiyan He, Zhongchen Song, Wei Zhou · 2025 · Frontiers in Cellular and Infection Microbiology
  32. Demystifying the link between periodontitis and oral cancer: a systematic review integrating clinical, pre-clinical, and in vitro data
    Suzane Cristina Pigossi, Jovânia Alves Oliveira, Marcell Costa de Medeiros, Lélio Fernando Ferreira Soares, Nisha J. D’Silva · 2025 · Cancer and Metastasis Reviews
  33. Can chronic oral inflammation and masticatory dysfunction contribute to cognitive impairment?
    Matthew R. Nangle, Nithin Manchery · 2019 · Current Opinion in Psychiatry
  34. Preparation, construction and high-throughput automated analysis of human brain tissue microarrays for neurodegenerative disease drug development
    Malvindar K. Singh‐Bains, Nasim F. Mehrabi, Adelie Y. S. Tan, Richard L. M. Faull, Mike Dragunow · 2021 · Nature Protocols
  35. Gut microbiome research in multiple sclerosis
    Daiki Takewaki, Takashi Yamamura · 2021 · Neuroscience Research
  36. Oral Microbiota Profile of Individuals Who Abuse Methamphetamine
    Yongde Yang, Xuan Yu, Xue Yang, Kuan Zeng, Guangya Liu, Wei Hao, Sheng Zhang, Gang Wang · 2021 · Frontiers in Cellular and Infection Microbiology
  37. Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides
    Gajender Aleti, Jordan N. Kohn, Emily A. Troyer, Kelly C. Weldon, Shi Wei Huang, Anupriya Tripathi, Pieter C. Dorrestein, Austin D.-E. Swafford, Rob D. Knight, Suzi Hong · 2022 · BMC Microbiology
  38. Do Oral Pathogens Inhabit the Eye and Play a Role in Ocular Diseases?
    Pachiappan Arjunan, Radhika Swaminathan · 2022 · Journal of Clinical Medicine
  39. Increased occurrence of Treponema spp. and double-species infections in patients with Alzheimer's disease
    Michal Nemergut, Tereza Batkova, Dana Vigašová, Milan Bartoš, Martina Hlozankova, Andrea Schenkmayerová, Barbora Lišková, Kateřina Sheardová, Martin Vyhnálek, Jakub Hort et al. · 2022 · The Science of The Total Environment
  40. Porphyromonas gingivalis: A key role in Parkinson's disease with cognitive impairment?
    Dongcheng Li, Tengzhu Ren, Hao Li, Geng Liao, Xiong Zhang · 2022 · Frontiers in Neurology
  41. Different oral and gut microbial profiles in those with Alzheimer's disease consuming anti-inflammatory diets
    Lili Chen, Bixia Wang, Jinxiu Liu, Xiaoqi Wu, Xinhua Xu, Huizhen Cao, Xinli Ji, Ping Zhang, Xiuli Li, Zhaoyi Hou et al. · 2022 · Frontiers in Nutrition
  42. Porphyromonas gingivalis Conditioned Medium Induces Amyloidogenic Processing of the Amyloid-β Protein Precursor upon in vitro Infection of SH-SY5Y Cells
    Shalini Kanagasingam, Christopher J. von Ruhland, Richard R. Welbury, Sasanka S. Chukkapalli, Sim K. Singhrao · 2022 · Journal of Alzheimer s Disease Reports
  43. Parvimonas micra can translocate from the subgingival sulcus of the human oral cavity to colorectal adenocarcinoma
    Kelly Conde‐Pérez, Elena Buetas, Pablo Aja‐Macaya, Elsa Martín‐De Arribas, Iago Iglesias‐Corrás, Noelia Trigo‐Tasende, Mohammed Nasser‐Ali, Lara S. Estévez, Soraya Rumbo‐Feal, Begoña Otero‐Alén et al. · 2023 · Molecular Oncology
  44. Peripheral inflammation is a potential etiological factor in Alzheimer’s disease
    Zi-Yuan Li, Hui Wang, Yafu Yin · 2023 · Reviews in the Neurosciences
  45. Immunotherapies Targeting Amyloid and Tau Protein in Alzheimer’s Disease: Should We Move Away from Diseases and Focus on Biological Targets? A Systematic Review and Expert Opinion
    Arthur Esquer, Frédéric Blanc, Nicolas Collongues · 2023 · Neurology and Therapy
  46. Mobile Point-of-Care Device Using Molecularly Imprinted Polymer-Based Chemosensors Targeting Interleukin-1β Biomarker
    Rowoon Park, Sangheon Jeon, Jae Won Lee, Jeonghwa Jeong, Y. Kwon, Sung Hyun Kim, Joonkyung Jang, Dong-Wook Han, Suck Won Hong · 2023 · Biosensors
  47. Oral microbiota–host interaction: the chief culprit of alveolar bone resorption
    Jingyu Xu, Ling Yu, Surong Ye, Zitong Ye, Luyi Yang, Xiaoxi Xu · 2024 · Frontiers in Immunology
  48. Gut Microbiota as a Modifier of Huntington’s Disease Pathogenesis
    Ali Khoshnan · 2024 · Journal of Huntington s Disease
  49. Microbiota in Human Periodontal Abscess Revealed by 16S rDNA Sequencing
    Jiazhen Chen, Xingwen Wu, Danting Zhu, Meng Xu, Youcheng Yu, Liying Yu, Wenhong Zhang · 2019 · Frontiers in Microbiology
  50. The Distinct Immune-Stimulatory Capacities of Porphyromonas gingivalis Strains 381 and ATCC 33277 Are Determined by the fimB Allele and Gingipain Activity
    Stephen R. Coats, Nutthapong Kantrong, Thao T. To, Sumita Jain, Caroline Attardo Genco, Jeffrey S. McLean, Richard P. Darveau · 2019 · Infection and Immunity
  51. Porphyromonas gingivalis infection may contribute to systemic and intracerebral amyloid-beta: implications for Alzheimer’s disease onset
    Ingar Olsen, Sim K. Singhrao · 2020 · Expert Review of Anti-infective Therapy
  52. Oral Microbially-Induced Small Extracellular Vesicles Cross the Blood–Brain Barrier
    Elashiry, Mahmoud, Carroll, Angelica, Yuan, Jessie, Liu, Yutao, Hamrick, Mark, Cutler, Christopher W., Wang, Qin, Elsayed, Ranya · 2024 · International Journal of Molecular Sciences
  53. Porphyromonas gingivalis Gingipains Destroy the Vascular Barrier and Reduce CD99 and CD99L2 Expression To Regulate Transendothelial Migration
    Zou, Zhaolei, Fang, Juan, Ma, Wanting, Guo, Junyi, Shan, Zhongyan, Ma, Da, Hu, Qiannan, Wen, Liling, Wang, Zhi · 2023 · Microbiology Spectrum
  54. Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
    Ambika Verma, Gohar Azhar, Pankaj Patyal, Wei Zhang, Xiaomin Zhang, Jeanne Y. Wei · 2024 · GeroScience
  55. Do microbes play a role in Alzheimer's disease?
    Zoë A. P. Williams, Léonie Láng, Sarah Nicolas, Gerard A. Clarke, John F. Cryan, David Vauzour, Yvonne M. Nolan · 2024 · Microbial Biotechnology
  56. Metal-organic frameworks for the diagnosis and treatment of Alzheimer’s disease: Current status and perspectives
    Guimei Zhang, Yanxin Shen, Joshua Phipps, Li Sun, Shengqian Ma · 2024 · Coordination Chemistry Reviews
  57. The root of the matter: Linking oral health to chronic diseases prevention
    Francesca D'Aiuto, Jean E. Suvan, Nisachon Siripaiboonpong, Michael Α. Gatzoulis, Francesco D’Aiuto · 2025 · International Journal of Cardiology Congenital Heart Disease
  58. Inflammatory Association between Periodontal Disease and Systemic Health
    Fajer Hasan, Ankit Tandon, Hawra AlQallaf, Vanchit John, Mithun Sinha, Monica P Gibson · 2025 · Inflammation
  59. Bacterial DNA induces the formation of heat-resistant disease-associated proteins in human plasma
    Victor Tetz, George V. Tetz · 2019 · Scientific Reports
  60. Flavorless vs. Flavored Electronic Cigarette-Generated Aerosol and E-Liquid on the Growth of Common Oral Commensal Streptococci
    Jacob S. Fischman, Swapna Sista, DongKeun Lee, Giancarlo A. Cuadra, Dominic L. Palazzolo · 2020 · Frontiers in Physiology
  61. Gender Variations in the Oral Microbiomes of Elderly Patients with Initial Periodontitis
    Jie Zhao, Yinghui Zhou, Ya‐Qiong Zhao, Yao Feng, Fei Yan, Zhengrong Gao, Qin Ye, Yun Chen, Qiong Liu, Li Tan et al. · 2021 · Journal of Immunology Research
  62. Kinetic Modulation of Amyloid-β (1–42) Aggregation and Toxicity by Structure-Based Rational Design
    Dongjoon Im, Chae Eun Heo, Myung Kook Son, Chae Ri Park, Hugh I. Kim, Jeong‐Mo Choi · 2022 · Journal of the American Chemical Society
  63. Peripheral Pathways to Neurovascular Unit Dysfunction, Cognitive Impairment, and Alzheimer’s Disease
    Amy R. Nelson · 2022 · Frontiers in Aging Neuroscience
  64. Subversion of the Oral Microbiota and Induction of Immune-Mediated Systemic Inflammation with Special Reference to Periodontitis: Current Knowledge and Perspectives
    Luigì Santacroce, Eleonora Lo Muzio, Lucrezia Bottalico, Francesca Spirito, Ioannis Alexandros Charitos, Pier Carmine Passarelli, Emilio Jirillo · 2022 · Endocrine Metabolic & Immune Disorders - Drug Targets
  65. Microbiome influences on neuro-immune interactions in neurodegenerative disease
    Kelly B. Menees, Brittney A. Otero, Malú G. Tansey · 2022 · International review of neurobiology
  66. Subgingival host–microbiome metatranscriptomic changes following scaling and root planing in grade II / III periodontitis
    Ana E. Duran-Pinedo, José Solbiati, Flavia Teles, Jorge Frias‐Lopez · 2022 · Journal Of Clinical Periodontology
  67. Bacteria-driven bio-therapy: From fundamental studies to clinical trials
    Yuxuan Yu, Sicen Lin, Zhichao Chen, Bin Y. Qin, Zhonggui He, Maosheng Cheng, Mengchi Sun, Jin Yuan Sun · 2022 · Nano Today
  68. High resolution 16S rRNA gene Next Generation Sequencing study of brain areas associated with Alzheimer’s and Parkinson’s disease
    David C. Emery, Maria Davies, Tanya L. Cerajewska, Jelena Taylor, Mae Hazell, Alex R. Paterson, Shelley Jane Allen, Nicola Xania West · 2022 · Frontiers in Aging Neuroscience
  69. Oral microbiome in older adults with mild cognitive impairment
    Dongxin Da, Qianhua Zhao, Hao Zhang, Wanqing Wu, Xiaoli Zeng, Xiaoniu Liang, Yiwei Jiang, Zhenxu Xiao, Jin Ming Yu, Saineng Ding et al. · 2023 · Journal of Oral Microbiology
  70. Impact of Porphyromonas gingivalis -odontogenic infection on the pathogenesis of non-alcoholic fatty liver disease
    Linbo Liu, Yan Geng, Chaoliang Xiong · 2023 · Annals of Medicine
  71. Bacteria Synergized with PD‐1 Blockade Enhance Positive Feedback Loop of Cancer Cells‐M1 Macrophages‐T Cells in Glioma
    Qi Chen, Yuyi Zheng, Xiaojie Chen, Yuan Xing, Jiajie Zhang, Xinyi Yan, Qi Zhang, Di Wu, Zhong Chen · 2024 · Advanced Science
  72. Chlamydia pneumoniae in Alzheimer's disease pathology
    Lalita Subedi, Bhakta Prasad Gaire, Yosef Koronyo, Maya Koronyo‐Hamaoui, Timothy R. Crother · 2024 · Frontiers in Neuroscience
  73. Innovative Therapeutic Strategies in Alzheimer’s Disease: A Synergistic Approach to Neurodegenerative Disorders
    Sarfaraz K. Niazi, Matthias Magoola, Zamara Mariam · 2024 · Pharmaceuticals
  74. Periodontal Pathogens and Neuropsychiatric Health
    Abhishek Wadhawan, Mark Allan Reynolds, Hina Makkar, Alison J. Scott, Eileen Potocki, Andrew J. Hoisington, Lisa A. Brenner, Aline Dagdag, Christopher A. Lowry, Yogesh Dwivedi et al. · 2020 · Current Topics in Medicinal Chemistry
  75. Proposing BCG Vaccination for Mycobacterium avium ss. paratuberculosis (MAP) Associated Autoimmune Diseases
    Coad Thomas Dow · 2020 · Microorganisms
  76. Microglial Cathepsin B and Porphyromonas gingivalis Gingipains as Potential Therapeutic Targets for Sporadic Alzheimer’s Disease
    Hiroshi Nakanishi, Saori Nonaka, Zhou Wu · 2020 · CNS & Neurological Disorders - Drug Targets
  77. Human Brain Neuropharmacology: A Platform for Translational Neuroscience
    Mike Dragunow · 2020 · Trends in Pharmacological Sciences
  78. Towards defining the outer membrane proteome of Porphyromonas gingivalis
    Paul D. Veith, Dhana G. Gorasia, Eric Charles Reynolds · 2020 · Molecular Oral Microbiology
  79. Cognitive dysfunction in young subjects with periodontal disease
    Simona Ioana Hategan, Sabrina A. Kamer, Ronald G. Craig, Cosmin G. Sinescu, Mony J. de Leon, Dragoş Cătălin Jianu, Cătălin Marian, Bianca I. Bora, Traian Flavius Dan, Claudiu Dumitru Bîrdac et al. · 2021 · Neurological Sciences
  80. Formaldehyde‐Crosslinked Nontoxic Aβ Monomers to Form Toxic Aβ Dimers and Aggregates: Pathogenicity and Therapeutic Perspectives
    Hang Zhao, Xuerong Huang, Zhiqian Tong · 2021 · ChemMedChem
  81. Treponema denticola Has the Potential to Cause Neurodegeneration in the Midbrain via the Periodontal Route of Infection—Narrative Review
    Flavio Pisani, Valerio Pisani, Francesca Arcangeli, Alice Harding, Simarjit Kaur Singhrao · 2023 · International Journal of Environmental Research and Public Health
  82. Dual Attention Aware Octave Convolution Network for Early-Stage Alzheimer's Disease Detection
    Banupriya Rangaraju, Thilagavathi Chinnadurai, Sarmiladevi Natarajan, Vishnu Raja · 2024 · Information Technology And Control
  83. Alzheimer's disease-like pathology induced by Porphyromonas gingivalis in middle-aged mice is mediated by NLRP3 inflammasome via the microbiota-gut-brain axis
    Pei Zhang, Yan Liu, Xin Jin, Zhaoliang Hu, Jucui Yang, Hao Xin Lu, Taijun Hang, Min Ok Song · 2024 · Journal of Alzheimer s Disease
  84. Association between oral microbiome and depression: A population-based study
    Ziyang Zheng, Mingzhang Xu, Keming Xiao, Ke Yu · 2025 · Journal of Affective Disorders
  85. Integrated oral-gut microbiota therapy: a novel perspective on preventing bacterial translocation for systemic disease management
    Jie Zhu, Ziyi Jiang, Fangli Yu, Li Gao, Xiaomei Wang, Qiang Wang · 2025 · Frontiers in Cellular and Infection Microbiology
  86. Enzymatic Characteristics and Activities of Gingipains from Porphyromonas gingivalis
    Tomoko Kadowaki · 2020 · Methods in molecular biology
  87. The Association of Periodontitis and Alzheimer’s Disease: How to Hit Two Birds with One Stone
    Tom Werber, Zsófia Bata, Eniko Szabo Vaszine, Dalida Borbála Berente, Anita Kamondi, Andras Attila Horvath · 2021 · Journal of Alzheimer s Disease
  88. Philosophy of Oral Hypofunction
    Shunsuke Minakuchi · 2021 · Gerodontology
  89. Antibacterial and antibiofilm activities of novel antimicrobial peptide DP7 against the periodontal pathogen Porphyromonas gingivalis
    Sijing Jiang, Xun Xiao, Jiajun Zheng, Shuang Lai, Yang Li, Jing Li, Chang Liu, Yiling Yang, Yangdong Mu · 2022 · Journal of Applied Microbiology
  90. Oral Lesions Associated with COVID-19 and the Participation of the Buccal Cavity as a Key Player for Establishment of Immunity against SARS-CoV-2
    José Roberto Gutiérrez-Camacho, Lorena Ávila-Carrasco, Maria Calixta Martínez-Vázquez, Idalia Garza Veloz, Sidere Monserrath Zorrilla-Alfaro, Veronica Gutierrez-Camacho, Margarita L. Martínez‐Fierro · 2022 · International Journal of Environmental Research and Public Health
  91. Kidney microbiota dysbiosis contributes to the development of hypertension
    Xinyu Liu, Jing Li, Yamei Zhang, Luyun Fan, Yanli Xia, Yong‐Yang Wu, Junru Chen, Xinyu Zhao, Qiannan Gao, Bing Xu et al. · 2022 · Gut Microbes
  92. Implications of oral streptococcal bacteriophages in autism spectrum disorder
    Tong Zhan, Xin Zhou, Yanan Chu, Tianxu Zhang, Jie Zhang, Xiaoyan Zhao, Zuqun Wang, Rui Ding, Qingren Meng, Jun Yu et al. · 2022 · npj Biofilms and Microbiomes
  93. Systemic Inflammation Causes Microglial Dysfunction With a Vascular AD phenotype
    Praveen Bathini, Isabel Dupanloup, Elena Zenaro, Eleonora Terrabuio, Amrei Fischer, Edona Ballabani, Marie‐Agnès Doucey, Lavinia Auber Alberi · 2022 · Brain Behavior & Immunity - Health
  94. Exogenous monocyte myeloid-derived suppressor cells ameliorate immune imbalance, neuroinflammation and cognitive impairment in 5xFAD mice infected with Porphyromonas gingivalis
    Cheng Xiao, Li Chi, Tianqiong Lin, Fengyin Liang, Zhong Pei, Jianbo Sun, Wei Teng · 2023 · Journal of Neuroinflammation
  95. Confounding in observational studies evaluating the association between Alzheimer's disease and periodontal disease: A systematic review
    Gustavo G. Nascimento, Fábio Renato Manzolli Leite, Caio Melo Mesquita, Maria Tereza Campos Vidigal, Guilherme Henrique Borges, Luiz Renato Paranhos · 2023 · Heliyon
  96. Revealing the mechanisms of blood–brain barrier in chronic neurodegenerative disease: an opportunity for therapeutic intervention
    Sixun Yu, Xin Chen, Tao Yang, Jingmin Cheng, Enyu Liu, Lingli Jiang, Min Song, Haifeng Shu, Yuan Ma · 2024 · Reviews in the Neurosciences
  97. Update and review of the gerodontology prospective for 2020's: Linking the interactions of oral (hypo)-functions to health vs. systemic diseases
    Yen Chun G. Liu, Shou‐Jen Lan, Hirohiko Hirano, Li-min Lin, Kazuhiro Hori, Chia‐Shu Lin, Samuel R. Zwetchkenbaum, Shunsuke Minakuchi, Andy Yen‐Tung Teng · 2020 · Journal of Dental Sciences
  98. Alzheimer’s Disease Genetics: A Dampened Microglial Response?
    Zena K. Chatila, Elizabeth M. Bradshaw · 2021 · The Neuroscientist
  99. Uncovering the Oral Dysbiotic Microbiota as Masters of Neutrophil Responses in the Pathobiology of Periodontitis
    Zsombor Prucsi, Alicja Płonczyńska, Jan Potempa, Maja Sochalska · 2021 · Frontiers in Microbiology
  100. The Viral Protein Corona Directs Viral Pathogenesis and Amyloid Aggregation
    Kariem Ezzat, Maria Pernemalm, Sandra Axberg Pålsson, Thomas C. Roberts, Peter Järver, Aleksandra Dondalska, Burcu Bestas, Michał J. Sobkowiak, Bettina Levänen, Magnus Carl Sköld et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)